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Drotin A (100/80 mg) Tablet

Manufactured byWalter Bushnell
ContainsAceclofenac (100 mg) + Drotaverine (80 mg)
Description
Drotin A (100/80 mg) Tablet is a combination medicine that consists of Aceclofenac and Drotaverine. It is mainly used in the treatment of muscular pain associated with spasms in adults. It can also be used to treat dysmenorrhoea (pain associated with period cramps). Drotin A (100/80 mg) Tablet can provide relief from pain and swelling that occurs due to muscle cramps and spasms. Drotin A (100/80 mg) Tablet works by blocking certain enzyme receptors that cause muscle spasms and preventing the release of substances called prostaglandins in the brain that cause pain and fever. It can provide relief from pain and swelling due to arthritic conditions but does not cure it. Drotin A (100/80 mg) Tablet may cause some side effects like dry mouth, nausea, vomiting, heartburn, stomach pain, loss of appetite, and diarrhoea. Do not use this medicine if you are allergic to it. Avoid driving vehicles or operating machines after taking this medicine as it may cause dizziness. Do not consume alcohol while using this medicine as it may worsen drowsiness. Drotin A (100/80 mg) Tablet should be taken with food, milk, or an antacid to avoid stomach irritation. For the ease of remembering, take it at the same time every day. Do not stop using this medicine even if you feel better after taking a few doses as abrupt stopping may worsen your condition and lead to more severe symptoms. Drotin A (100/80 mg) Tablet may not be suitable for all people. Inform your doctor if you have liver or kidney problems before taking this medicine. This medicine is not recommended to be used if you are pregnant or are breastfeeding. Drotin A (100/80 mg) Tablet is not recommended for use in children below 12 years of age.

Side effects

Major & minor side effects for Drotin A (100/80 mg) Tablet

  • Dry mouth
  • Change in pulse rate
  • Dizziness
  • Headache
  • Swelling of face, lips, eyelids, tongue, hands and feet
  • Abdominal pain
  • Constipation
  • Diarrhoea
  • Nausea and vomiting
  • Skin rash

Uses of Drotin A (100/80 mg) Tablet

What is it prescribed for?

  • Muscular pain with spasm
  • Dysmenorrhea
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for Drotin A (100/80 mg) Tablet to show its action is not known.
  • How long do the effects of this medicine last?
    The amount of time for which Drotin A (100/80 mg) Tablet remains active in the body is not known.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended while taking Drotin A (100/80 mg) Tablet due to the increased risk of stomach bleeding and ulcer formation.
  • Is this a habit forming medicine?
    No-habit forming tendency has been reported for Drotin A (100/80 mg) Tablet.
  • Can this medicine be taken during pregnancy?
    Drotin A (100/80 mg) Tablet is not recommended for use during pregnancy due to the risk of harmful effects on your foetus. Consult your doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    It is not known whether Drotin A (100/80 mg) Tablet passes into breast milk or not. However, consult your doctor before taking this medicine.

Allergy

Avoid taking Drotin A (100/80 mg) Tablet if you are allergic to it. Serious allergic reactions to this medicine are rare. However, seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.

Severe liver/kidney diseases

Use of Drotin A (100/80 mg) Tablet should be avoided if you have any kidney or liver problems as it may increase the risk of worsening your condition.

Heart diseases

Drotin A (100/80 mg) Tablet should be used with caution if you have heart problems like congestive heart failure due to the risk of complications and worsening your condition.

Asthma

Drotin A (100/80 mg) Tablet should be used with caution if you have Asthma especially if you experience allergic reactions with the use of non-steroidal anti-inflammatory medicines (medicines used in the treatment of pain and fever) like aspirin.

Blood clotting disorder

Drotin A (100/80 mg) Tablet may prolong the blood clotting time and therefore increase the risk of bleeding. Hence, it is not recommended for use if you have blood clotting disorders as it may worsen your condition.
Warnings for special population

Pregnancy

Drotin A (100/80 mg) Tablet is not recommended for use during pregnancy due to the risk of harmful effects on your foetus. Consult your doctor before taking this medicine.

Breast-feeding

It is not known whether Drotin A (100/80 mg) Tablet passes into breast milk or not. However, consult your doctor before taking this medicine.
General warnings

Liver/kidney diseases

Drotin A (100/80 mg) Tablet should be used with caution if you have liver or kidney problems as it may cause serious side effects and lead to kidney/liver damage.

Hypotension

Drotin A (100/80 mg) Tablet may cause hypotension (low blood pressure) if you have pre-existing heart conditions like stroke, myocardial infarction etc. Your doctor may suggest tests for monitoring your heart function while on treatment with this medicine.

CABG

Do not use Drotin A (100/80 mg) Tablet for relieving pain after a CABG (coronary artery bypass graft) procedure as it may affect the clotting factors and may worsen your condition and impact the surgical outcome.

Use in children

Drotin A (100/80 mg) Tablet is not recommended for use in children below 18 years of age.

Driving or operating machiners

Drotin A (100/80 mg) Tablet may cause drowsiness or dizziness in some people. It is advised that you do not perform activities such as driving vehicles or operating machines if you experience any of these symptoms during treatment with this medicine.

Use in Elderly

Drotin A (100/80 mg) Tablet should be used with caution in elderly people due to the increased risk of kidney and liver damage. Your doctor will generally start treatment with lower doses to check for your tolerance to this medicine.

Water retention

Drotin A (100/80 mg) Tablet may cause oedema (water retention in your body's tissues majorly in lower limbs). Your doctor may suggest tests to monitor your blood pressure, electrolyte levels, and heart function while you are on treatment with this medicine based on your clinical condition.

Missed Dose

If you forget to take a dose of Drotin A (100/80 mg) Tablet, make sure that you remember to take your next dose when it is due. Do not take two doses together to make up for a missed one.

Overdose

Never take more than the prescribed dose of Drotin A (100/80 mg) Tablet. If you suspect that you might have taken an overdose of this medicine, seek emergency medical help.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended while taking Drotin A (100/80 mg) Tablet due to the increased risk of stomach bleeding and ulcer formation.
Interaction with Medicine

Lithium

Digoxin

Corticosteroids

Antihypertensives

Levodopa

Diazepam

Disease interactions

Porphyria

Porphyria is a rare disorder that mainly affects your skin or nervous system. This disorder is usually inherited, which means it is caused by gene mutations passed from parents to children. Drotin A (100/80 mg) Tablet may worsen the conditions associated with photosensitivity, such as acute porphyria. Consult your doctor before using this medicine in such conditions.

Low cardiac output

Avoid using Drotin A (100/80 mg) Tablet if you have a known history of low cardiac output (a condition characterized by insufficient pumping of blood from the heart) as it may worsen your condition.

Asthma

If you have NSAID-sensitive asthma, you may experience severe side effects including breathing difficulty while using Drotin A (100/80 mg) Tablet as it contains aceclofenac. Your doctor may adjust the dose of this medicine or prescribe a safer alternative based on your condition.

Gastro-Intestinal toxicity

Long term use of Drotin A (100/80 mg) Tablet can cause damage to the stomach and intestine. Serious conditions like bleeding, ulceration, and perforation of the stomach or intestinal wall can occur as a result of prolonged usage.

Kidney damage

Prolonged use of high doses of Drotin A (100/80 mg) Tablet may cause damage to the kidney and lead to problems, such as painful urination and protein or blood in the urine. Your doctor may suggest tests for monitoring your kidney function while on treatment with this medicine.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Drotin A (100/80 mg) Tablet with food to avoid stomach irritation. Never take more than the prescribed dose. Take this medicine at around the same time daily. Do not stop the use of this medicine without consulting your doctor. Take it in dose and duration prescribed by your doctor. Long-term use may lead to complications such as stomach bleeding and kidney problems. Do not drive vehicles or operate machines if you experience dizziness and drowsiness after taking this medicine. Avoid alcohol consumption while on treatment with this medicine. Do not take it with any other medicine containing Paracetamol or any drugs for pain/fever or cough-and-cold, without consulting your doctor first. Your doctor may regularly monitor your kidney, liver, heart function and levels of blood components if you are taking this medicine for a longer duration. Keep away from the reach of children and pets. Do not use it after the date of expiry.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works
Aceclofenac works by reducing the formation of certain substances in the body that cause pain and swelling. Drotaverine affects certain enzyme receptors that are directly involved with the spasms of the smooth muscles. It also helps in restoring the chemical balance in smooth muscles to relieve pain and spasms.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Nonsteroidal anti-inflammatory agents, Anticholinergics/antispasmodics

Schedule

Schedule H

Pubchem.ncbi.nlm.nih.gov. 2021. Aceclofenac. [online] Available at: < [Accessed 7 May 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Aceclofenac>

K.M, V. and D, A., 2021. Oral Drotaverine and Aceclofenac Combination versus Aceclofenac alone for Postoperative Pain Relief: A Prospective Randomized Clinical Trial. [online] Ijopp.org. Available at: < [Accessed 31 May 2021].

http://www.ijopp.org/article/42>

Dailymed.nlm.nih.gov. 2021. DailyMed - CLANZA CR- aceclofenac tablet, film coated. [online] Available at: < [Accessed 7 October 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=8a023942-01e8-4849-aa3c-1a640ffc7fd3>

Pubchem.ncbi.nlm.nih.gov. 2021. Drotaverine. [online] Available at: < [Accessed 31 May 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Drotaverine>

Drugs.ncats.io. 2021. NCATS Inxight: Drugs — DROTAVERINE. [online] Available at: < [Accessed 7 October 2021].

https://drugs.ncats.io/drug/98QS4N58TW>
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Information on this page was last updated on 12 Oct 2021

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