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Drotavin MF Tablet

Manufactured bySYNOKEM PHARMACEUTICALS LTD
ContainsDrotaverine (80 mg) + Mefenamic acid (250 mg)
Description

Drotavin MF Tablet is a combination medicine which may be used to treat mild to moderate pain associated with spasm in conditions such as irritable bowel syndrome, menstrual periods, etc.

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Side effects

Major & minor side effects for Drotavin MF Tablet

  • Nausea and Vomiting
  • Diarrhea
  • Constipation
  • Bloating
  • Headache
  • Dizziness
  • Ringing or buzzing in the ears
  • Blurred vision
  • Weight gain
  • Shortness of breath
  • Peeling and blistering of skin
  • Fast heartbeat
  • Unusual bleeding or bruising
  • Yellow colored eyes or skin
  • Difficult or painful urination
  • Bloody and Cloudy urine
  • Excessive tiredness

Uses of Drotavin MF Tablet

What is it prescribed for?

  • Mild to Moderate Pain associated with Muscle Spasm
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of this medicine can be observed within 20-30 minutes of administration.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of serious side effects such as severe gastrointestinal bleeding, dizziness, fatigue, weakness, rashes, nausea, joint pain, fever, etc.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on the clinical condition.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to mefenamic acid, other NSAIDs, drotaverine, or any other inactive ingredients present in the formulation.

Sever liver impairment

This medicine is not recommended for use in patients with severe liver diseases due to the increased risk of serious adverse effects.

Severe kidney impairment

This medicine is not recommended for use in patients with severe kidney diseases due to the increased risk of serious adverse effects.

Heart Failure

This medicine is not recommended for use in patients suffering from a condition characterized by insufficient pumping of blood, due to the increased risk of worsening of the patient's condition.

Coronary Artery Bypass Surgery (CABG)

This medicine is not recommended for use if you have undergone coronary artery bypass surgery recently.

Other allergic conditions

This medicine is not recommended for use if you have a allergic condition like asthma, urticaria, or any other allergic condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on the clinical condition.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Other medicines

This combination medicine may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you report all your current medicines including herbs and supplements to the doctor before beginning treatment with this medicine.

Effect on heart

This medicine should be used with caution in patients with heart diseases due to the increased risk of adverse effects on the heart, especially after prolonged use. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Fluid retention and edema

Use of this medicine may cause fluid retention and edema in some patients. Close monitoring of blood pressure, electrolyte levels, and heart function may be required based on the clinical condition. Appropriate dose adjustments or replacement with a suitable alternative may be necessary in some cases.

Allergic skin reaction

Use of this medicine may cause fatal skin allergies without any warnings in some patients. Signs and symptoms such as rashes, hives, fever, or other allergic symptoms should be reported to the doctor without any delay. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.

Liver disease

This medicine should be used with extreme caution in patients suffering from liver function impairment or active liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Kidney disease

This medicine should be used with caution in patients suffering from kidney diseases due to the increased risk of serious adverse effects. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.

Hypotension

Use of this medicine may cause a fall in blood pressure levels. This risk is especially higher in patients with a history of cardiovascular diseases. Close monitoring of blood pressure is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Gastro-intestinal toxicity

This medicine may cause severe gastrointestinal bleeding and perforation after prolonged usage. These adverse events may occur with or without warning symptoms. This risk is especially higher in the elderly population and in patients with a history of gastrointestinal diseases. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Driving or Operating machinery

Use of this medicine may cause dizziness, blurred vision, etc in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Missed Dose

Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of serious side effects such as severe gastrointestinal bleeding, dizziness, fatigue, weakness, rashes, nausea, joint pain, fever, etc.
Interaction with Medicine

Glimepiride

Atropine

Diclofenac

Levodopa

Diazepam

Warfarin

Disease interactions

Asthma

This medicine is not recommended for use in patients with a known history of NSAID-sensitive asthma. Replacement with a suitable alternative should be done under your doctor's supervision.

Skin rash and peeling

Use of this medicine can cause these fatal skin allergies without any warnings. Signs and symptoms like rashes, hives, fever or other allergic symptoms should be reported without any delay. Appropriate corrective measures, appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Kidney Disease

This medicine should be used with caution in patients with kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Liver Disease

This medicine should be used with caution in patients with liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Porphyria

This medicine should be used with extreme caution in patients with a known history of Porphyria due to the increased risk of worsening of the patient's condition. Appropriate corrective measures or replacement with a suitable alternative may be required based on the clinical condition.

Gastro-Intestinal toxicity

This medicine may cause damage to the stomach, intestines, liver, etc., especially on prolonged use. Report any symptoms such as chronic indigestion, blood in stool or vomit, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine, as instructed by your doctor. Do not take in larger amounts or for longer durations than prescribed. It can be taken with food or immediately after food to minimize stomach irritation. Report any unusual symptoms to the doctor immediately. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works
Drotaverine acts on the smooth muscles to relieve pain and spasms. Mefenamic acid works by stopping the production of certain chemicals in the body that causes swelling, pain, and fever.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Nonsteroidal anti-inflammatory agents, Anticholinergics/antispasmodics

Schedule

Schedule H

Drotaverine HCL 80 mg & Mefenamic acid IP 250 mg - Manufacturer,Supplier,Exporter [Internet]. Talenthealthcare.org. 2018 [cited 15 November 2018]. Available from:

http://www.talenthealthcare.org/drotaverine-hcl-80-mg-mefenamic-acid-ip-250-mg-3216505.html

MEFPURE D | Drotaverine hydrochloride 80mg + Mefenamic Acid 250 mg [Internet]. Innovexia.com. 2018 [cited 15 November 2018]. Available from:

http://www.innovexia.com/product/mefpure-d

Drotaverine - DrugBank [Internet]. Drugbank.ca. 2017 [cited 22 May 2017]. Available from:

https://www.drugbank.ca/drugs/DB06751

Mefenamic acid - DrugBank [Internet]. Drugbank.ca. 2017 [cited 30 May 2017]. Available from:

https://www.drugbank.ca/drugs/DB00784
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Information on this page was last updated on 5 Jul 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.