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Dompan Forte Tablet

Manufactured byMedley Pharmaceuticals
ContainsPantoprazole (40 mg) + Domperidone (15 mg)
Description
Dompan Forte Tablet is a combination of Domperidone and Pantoprazole. It is used in the treatment of peptic ulcers (sores that occur on the lining of your stomach and the upper region of your small intestine) and gastroesophageal reflux disease (a condition where the stomach acid flows back into the food pipe and damages it). These conditions lead to symptoms such as heartburn, discomfort in the stomach, vomiting sensation, and difficulty in swallowing food. Dompan Forte Tablet reduces the sensation of nausea and decreases the production of stomach acid. Thus, it helps to heal ulcers. Dompan Forte Tablet shows some common side effects like headache, dry mouth, stomach pain/discomfort, diarrhoea, and dizziness. Consult your doctor if these side effects persist or worsen. Dompan Forte Tablet should be taken one hour before your meal. The dose and duration of treatment will be decided by your doctor based on your condition. Take this medicine for the complete duration prescribed by your doctor. If you stop this medicine early, your symptoms may reappear or your condition may worsen. Dompan Forte Tablet should be avoided if you are allergic to it. Inform your doctor if you have liver, kidney, heart, and/or bone problems, or if you are taking any medications. Dompan Forte Tablet is not recommended for use in children below 12 years of age due to limited safety and efficacy data. Consult your doctor if you are pregnant, or are breastfeeding.

Side effects

Major & minor side effects for Dompan Forte Tablet

  • Headache
  • Altered sense of taste
  • Diarrhoea
  • Unusual tiredness and weakness
  • Skin rash
  • Irregular heartbeat
  • Breast pain and tenderness
  • Dry mouth
  • Dizziness

Uses of Dompan Forte Tablet

What is it prescribed for?

  • Gastroesophageal Reflux Disease
  • Peptic Ulcer
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of Dompan Forte Tablet is seen within 30 to 60 minutes.
  • How long do the effects of this medicine last?
    The effect of Dompan Forte Tablet remains in your body for an average duration of 24 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    Dompan Forte Tablet has no habit forming tendency.
  • Can this medicine be taken during pregnancy?
    Dompan Forte Tablet is not recommended for use during pregnancy. Hence, consult your doctor if you are pregnant.
  • Can this medicine be taken while breast-feeding?
    Dompan Forte Tablet may pass into breastmilk and may harm your baby. Hence, consult your doctor if you are breastfeeding.

Allergy

Avoid taking Dompan Forte Tablet if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling of the face/tongue/throat, breathing difficulty, etc.

Prolactinoma

Prolactinoma is a tumour of the pituitary gland which leads to an increase in prolactin (a hormone responsible for milk production in lactating women). The symptoms in women are infertility, irregular periods, and acne. Avoid taking Dompan Forte Tablet as it may worsen your health condition.

Heart diseases

Dompan Forte Tablet may cause irregular heartbeat. Hence, this medicine is not recommended if you have pre-existing heart conditions like congestive heart failure (a condition in which your heart is not able to pump sufficient blood throughout the body), QT prolongation (heart muscle takes longer than normal to recharge between a heartbeat), etc., as it may worsen your health condition.

Moderate to severe liver impairment

Dompan Forte Tablet is broken down in the liver. Hence, this medicine is not recommended if you have moderate to severe liver problems as it may cause further liver damage.
Warnings for special population

Pregnancy

Dompan Forte Tablet is not recommended for use during pregnancy. Hence, consult your doctor if you are pregnant.

Breast-feeding

Dompan Forte Tablet may pass into breastmilk and may harm your baby. Hence, consult your doctor if you are breastfeeding.
General warnings

Other medicines

Inform your doctor about the use of all your medicines including any herbs and supplements as Dompan Forte Tablet may interact with other medications and cause side effects.

Use in children

Dompan Forte Tablet is not recommended for use in children below 12 years of age as the safety and efficacy data are not clinically established.

Use in elderly

Dompan Forte Tablet should be used with caution in elderly people. The activity of the liver and kidney decreases with age and this may lead to an increased risk of side effects while taking this medicine.

Prolactin imbalance

Taking Dompan Forte Tablet for a long time or at higher doses increases the level of prolactin hormone in your body. This may lead to side effects like infertility and irregular periods. The increased levels of prolactin may fall to normal after discontinuation of the medicine.

Driving or operating machines

Dompan Forte Tablet may cause visual disturbances or dizziness. Hence, avoid driving vehicles and operating heavy machines after taking this medicine until you know how this medicine affects you.

Effect on heart

Dompan Forte Tablet can increase the risk of abnormal heartbeat or other heart problems. The risk may be higher if you are older than 60 years or if you are taking a higher dose of this medicine.

Missed Dose

Try not to skip the dose of Dompan Forte Tablet. In case you missed a dose, take it as soon as you remember. If the delay is more than 12 hours, skip the dose. Do not take a double dose to make up for the missed dose.

Overdose

Never take more than the prescribed dose of Dompan Forte Tablet. In case of an overdose, seek immediate medical attention.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Digoxin

Methotrexate

Warfarin

Nelfinavir

Ketoconazole

Disease interactions

Osteoporosis

Osteoporosis is a condition in which bones become weak. This medicine decreases calcium absorption in your body leading to a deficiency of calcium required to maintain bone density. Hence, long-term use of Dompan Forte Tablet is not recommended as it can lead to decreased bone strength. Your doctor may suggest tests to monitor your bone health and mineral status while you are taking this medicine.

Hypomagnesaemia

Long-term use of Dompan Forte Tablet may result in hypomagnesaemia (low magnesium levels in your blood). Inform your doctor if you experience any symptoms such as dizziness, irregular heartbeat, shivering, muscle pain, seizures (fits), etc. Your doctor may suggest tests to check magnesium levels in your blood at regular intervals. Consult your doctor if you have any concerns.

Kidney Disease

If you have severe kidney problems, use Dompan Forte Tablet with caution as prolonged use may increase the accumulation of this medicine in your body.
Food interactions
Information not available.
Lab interactions

Tetrahydrocannabinol (THC)

There may be a false-positive result of urine screening for tetrahydrocannabinol if you are taking Dompan Forte Tablet. Inform your doctor or lab technician about the use of this medicine before the lab test.
Take Dompan Forte Tablet one hour before meal. Do not chew or crush the tablet. Avoid taking more than the prescribed dose. Take this medicine for the recommended duration. Avoid taking food and drinks such as peppermint, chocolates, spicy food, coffee, alcoholic drinks, etc. as it may worsen your symptoms. Avoid driving and operating heavy machines as this medicine may cause visual disturbances and dizziness.
Miscelleneous

To be taken on an empty stomach

To be taken as instructed by doctor

May cause sleepiness

How it works
Dompan Forte Tablet is a combination of Domperidone and Pantoprazole. This combination works effectively in reducing stomach acid and preventing vomiting. Domperidone works by increasing the movement of the food through your stomach into the intestine thus, it prevents vomiting. Pantoprazole works by decreasing the production of acid in your stomach.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Antiemetics, Proton pump inhibitors

Schedule

Schedule H

Pubchem.ncbi.nlm.nih.gov. 2021. Domperidone. [online] Available at: < [Accessed 10 August 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Domperidone>

Pubchem.ncbi.nlm.nih.gov. 2021. Pantoprazole. [online] Available at: < [Accessed 10 August 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Pantoprazole>

nhs.uk. 2021. Domperidone: anti-sickness medicine used to treat nausea and vomiting. [online] Available at: < [Accessed 6 August 2021].

https://www.nhs.uk/medicines/domperidone/>

Medicines.org.uk. 2021. Pantoprazole 40 mg gastro-resistant tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 12 November 2021].

https://www.medicines.org.uk/emc/product/7090/smpc>

Medsafe.govt.nz. 2021. Domperidone (Motilium, Prokinex) – conclusion of review of benefits and risks of harm. [online] Available at: < [Accessed 12 November 2021].

https://www.medsafe.govt.nz/safety/ews/2014/Domperidone.asp>
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Information on this page was last updated on 17 Nov 2021

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