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Domel 10 MG Tablet

Manufactured byIntas Pharmaceuticals Ltd.
ContainsDomperidone
Description
Domel 10 MG Tablet is an effective anti-emetic medicine used to relieve nausea and vomiting caused by delayed gastric emptying (the time it takes for food to empty from the stomach and enter the small intestine). It increases intestinal movements and facilitates the emptying of the bowel. It is used alone or in combination with other medicines for relieving nausea, vomiting and indigestion. Domel 10 MG Tablet works by blocking certain substances that trigger nausea or vomiting. Domel 10 MG Tablet may cause side effects like headache, dry mouth, and stomach pain. Most of these are temporary and usually resolve with time. Consult your doctor if these symptoms persist. Domel 10 MG Tablet may also cause dizziness. Do not drive or do anything that requires mental focus after taking this medicine. This medicine may also cause diarrhoea, so it is better to take plenty of fluids while taking this medicine as it helps to prevent dehydration. Domel 10 MG Tablet can be taken 30 minutes before having food. Use it as directed by your doctor. Avoid taking this medicine if you are allergic to it. Do not drink alcohol while taking this medicine as it can worsen the side effects. Domel 10 MG Tablet is not recommended for use in children below 12 years of age due to the lack of safety data. Inform your doctor if you are pregnant, planning a pregnancy or breastfeeding before taking this medicine. If you have liver, kidney or gastrointestinal bleeding problems, inform your doctor before taking Domel 10 MG Tablet.

Side effects

Major & minor side effects for Domel 10 MG Tablet

  • Swelling of face, lips, eyelids, tongue, hands and feet
  • Difficulty in breathing
  • Skin rash
  • Irregular heartbeat
  • Disrupted menstrual cycle
  • Breast pain and tenderness
  • Dry mouth
  • Chest pain
  • Dizziness and fainting
  • Extreme tiredness

Uses of Domel 10 MG Tablet

What is it prescribed for?

  • Nausea and vomiting
  • Gastric motility disorders
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effects of Domel 10 MG Tablet can be observed within 30 to 60 minutes after taking it.
  • How long do the effects of this medicine last?
    The effect of Domel 10 MG Tablet lasts for an average duration of 6 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with Domel 10 MG Tablet due to the increased risk of serious side effects such as dizziness, drowsiness, difficulty concentrating, gastrointestinal bleeding, weakness, fatigue, etc.
  • Is this a habit forming medicine?
    No habit forming tendencies were reported for Domel 10 MG Tablet.
  • Can this medicine be taken during pregnancy?
    Domel 10 MG Tablet is not recommended for use in pregnant women as sufficient data is not available regarding its safety. Your doctor may prescribe this medicine only if the benefits outweigh the risk. Do not take or stop this medicine without consulting with your doctor.
  • Can this medicine be taken while breast-feeding?
    Domel 10 MG Tablet is not recommended for use in breastfeeding. An alternate medicine may be preferred. Consult your doctor to discuss potential risks and benefits.

Allergy

Avoid using Domel 10 MG Tablet if you are allergic to it. If you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), dizziness, breathing difficulty, etc., seek immediate medical attention.

Tumor of Pituitary gland

Domel 10 MG Tablet is not recommended for use if you have a prolactin-releasing tumour of the pituitary gland as this medicine is known to have a prolactin-releasing effect which can affect you, and may increase the risk of worsening your condition.

Heart diseases

Domel 10 MG Tablet is not recommended for use if you have any heart disease like congestive heart failure as it can result in QT prolongation, hence affecting the electrical working of the heart. This can increase the risk of worsening your condition.

Moderate to severe liver impairment

Domel 10 MG Tablet is not recommended if you have moderate to severe liver disease as poorly functioning liver takes a longer time to metabolize the medicine which increases the risk of toxicity in the blood.
Warnings for special population

Pregnancy

Domel 10 MG Tablet is not recommended for use in pregnant women as sufficient data is not available regarding its safety. Your doctor may prescribe this medicine only if the benefits outweigh the risk. Do not take or stop this medicine without consulting with your doctor.

Breast-feeding

Domel 10 MG Tablet is not recommended for use in breastfeeding. An alternate medicine may be preferred. Consult your doctor to discuss potential risks and benefits.
General warnings

Other medicines

Domel 10 MG Tablet may interact with many other medicines and cause severe adverse effects. Hence, it is advised to inform your doctor about all your current medicines before starting the treatment.

Use in children

Domel 10 MG Tablet is not recommended for use in children less than 12 years of age and weighing less than 35 kg since the safety and efficacy data is not available.

Use in elderly population

Domel 10 MG Tablet should be used with caution in elderly people. The risk of adverse effects is significantly high and hence treatment should begin with the lowest possible dose.

Electrolyte imbalance

Domel 10 MG Tablet should be used with extreme caution if you are with acute or long-term electrolyte imbalance due to the increased risk of worsening your condition. Regular monitoring of electrolyte levels is recommended. Your doctor may adjust the dose if required.

Prolactin imbalance

Domel 10 MG Tablet may cause an imbalance in the levels of prolactin, resulting in disturbances in the menstrual cycle in women. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Dosage and duration of uptake

Domel 10 MG Tablet should be used for the shortest duration possible. The dose should be kept as low as possible. Self-administration is not advised owing to these reasons.

Driving or operating machinery

Domel 10 MG Tablet may cause dizziness, confusion, or disorientation and hence do not perform any activities such as driving a vehicle or operating machinery after taking this medicine.

Missed Dose

If you forget to take a dose of Domel 10 MG Tablet, take it as soon as you remember. Do not take a double dose to make up for the missed one.

Overdose

Do not take more than the prescribed dose. Seek emergency medical attention if you suspect that you might have taken an overdose of Domel 10 MG Tablet.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with Domel 10 MG Tablet due to the increased risk of serious side effects such as dizziness, drowsiness, difficulty concentrating, gastrointestinal bleeding, weakness, fatigue, etc.
Interaction with Medicine

Cisapride

Erythromycin

Ketoconazole

Tramadol

Disease interactions

Kidney diseases

Domel 10 MG Tablet should be used with extreme caution if you have any kidney diseases as a diseased kidney will not completely eliminate this medicine from the blood, which increases the risk of toxicity.

Liver disease

Domel 10 MG Tablet should be used with extreme caution if you have liver diseases due to the increased risk of serious adverse effects and worsening your condition. Your doctor may monitor your liver function and may adjust the dose of this medicine if required based on your condition.

Gastro-intestinal disease

Use Domel 10 MG Tablet with extreme caution if you have any gastrointestinal disease, particularly colitis (swelling of the inner lining of the colon), since it may worsen your condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Domel 10 MG Tablet should be taken half an hour before food as directed by the doctor. The dose and duration of this medicine will be decided by your doctor. Do not take in larger or smaller quantities than recommended. Take plenty of water, have a fibre-rich diet, avoid foods that trigger your symptoms, exercise regularly to get better results. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. This medicine is not recommended for use in pregnancy and breastfeeding. Caution should be maintained if you have any kidney or liver problems during the treatment course.
Miscelleneous

To be taken before food

To be taken as instructed by doctor

May cause sleepiness

How it works
Domel 10 MG Tablet works by blocking certain chemicals messengers (dopamine) in the vomiting centre of your brain and acts on the upper digestive tract to increase the movement of the stomach and intestines. This causes faster gastric emptying and helps in the prevention of nausea and vomiting.
Legal Status

Approved

Banned

Approved

Approved

Classification

Category

Antiemetics

Schedule

Schedule H

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https://assets.publishing.service.gov.uk/media/54730802e5274a130300002d/con418525.pdf>

Pubchem.ncbi.nlm.nih.gov. 2021. Domperidone. [online] Available at: < [Accessed 24 June 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/3151>

Medicines.org.uk. 2021. Domperidone 10mg Tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 24 June 2021].

https://www.medicines.org.uk/emc/medicine/23098>

Medsafe.govt.nz. 2021. [online] Available at: < [Accessed 24 June 2021].

https://www.medsafe.govt.nz/Consumers/CMI/d/domperidone.pdf>
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Information on this page was last updated on 7 Sep 2021

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