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Doloneuron NT 100 Tablet

Manufactured byPULSE PHARMACEUTICALS PVT LTD
ContainsGabapentin (100 mg) + Nortriptyline (10 mg)
Description
Doloneuron NT 100 Tablet is a combination of Gabapentin and Notriptyline. It is used for the treatment of neuropathic pain (nerve pain that occurs due to damage or injury to the nerves that transfer information to the brain from the skin, muscles, and other parts of the body). Doloneuron NT 100 Tablet works by blocking the transmission of pain signals in your brain. Doloneuron NT 100 Tablet shows some common side effects like constipation, weight gain, dry mouth, difficulty in urination, nausea, etc. Consult your doctor if these side effects remain for a long time or worsen. Avoid driving vehicles or operating machines after taking this medicine as it can make you dizzy or drowsy. Doloneuron NT 100 Tablet can be taken with or without food. Take it at the same time every day for the ease of remembering and to maintain a constant level in your body. The correct dose should be taken as recommended by your doctor. Avoid taking more or less than the recommended dose as it may alter the effects of this medicine or increase the risk of side effects. If you miss a dose, take it as soon as you remember. Skip the dose if it is near to the next scheduled dose. Do not take a double dose to make up for the missed one. Doloneuron NT 100 Tablet is not recommended for use if you are allergic to it or have a history of a heart attack. Avoid consumption of alcohol while taking this medicine as it may increase the risk of side effects such as dizziness and sleepiness. This medicine should be used with caution if you have liver or kidney problems. Hence consult your doctor for further guidance. Doloneuron NT 100 Tablet is not recommended for use in children below 18 years of age due to the lack of safety and efficacy data. If you are pregnant or breastfeeding, consult your doctor before taking this medicine.

Side effects

Major & minor side effects for Doloneuron NT 100 Tablet

  • Dizziness and Drowsiness
  • Unusual tiredness and weakness
  • Constipation
  • Weight gain
  • Dry mouth
  • Blurred vision
  • Fast heart rate
  • Nervousness and irritability
  • Decreased interest in sexual intercourse
  • Skin rash
  • Difficulty in urination

Uses of Doloneuron NT 100 Tablet

What is it prescribed for?

  • Neuropathic pain
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for Doloneuron NT 100 Tablet show its action is not known.
  • How long do the effects of this medicine last?
    The amount of time for Doloneuron NT 100 Tablet remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with Doloneuron NT 100 Tablet as it may increase the risk of side effects like dizziness, drowsiness, and difficulty in concentration.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Doloneuron NT 100 Tablet.
  • Can this medicine be taken during pregnancy?
    Animal studies indicate that Doloneuron NT 100 Tablet may cause harm to the developing foetus. However, due to the lack of safety studies in humans, consult your doctor to understand the potential risk and benefits before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    Doloneuron NT 100 Tablet may pass into breastmilk. Therefore, it is not recommended for use while breastfeeding unless necessary. Consult your doctor before taking this medicine if you are breastfeeding.

Allergy

Avoid taking Doloneuron NT 100 Tablet if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.

Heart attack

A heart attack is an emergency medical condition in which part of the heart muscle does not get enough blood due to a disruption in blood flow to the heart. Doloneuron NT 100 Tablet is not recommended for use if you are recovering from a heart attack. This medicine may alter the functioning of your heart and worsen your condition.
Warnings for special population

Pregnancy

Animal studies indicate that Doloneuron NT 100 Tablet may cause harm to the developing foetus. However, due to the lack of safety studies in humans, consult your doctor to understand the potential risk and benefits before taking this medicine.

Breast-feeding

Doloneuron NT 100 Tablet may pass into breastmilk. Therefore, it is not recommended for use while breastfeeding unless necessary. Consult your doctor before taking this medicine if you are breastfeeding.
General warnings

Driving or operating machines

Doloneuron NT 100 Tablet may cause dizziness, confusion, or drowsiness. Hence, avoid performing activities that require mental alertness, like driving vehicles or operating machines while taking this medication.

Suicidal tendencies

Doloneuron NT 100 Tablet may increase the risk of suicidal thoughts and behaviour. Therefore, it should be used with caution, especially if you have depression. Consult your doctor immediately if you experience changes in mood and behaviour or thoughts of self-harm.

Withdrawal symptoms

Doloneuron NT 100 Tablet should be taken for the prescribed duration even if you experience an improvement in your condition. If you discontinue this medicine suddenly, you may experience withdrawal symptoms such as anxiety, sleeping difficulties, excessive sweating, nausea, and vomiting. Hence your doctor may gradually reduce the dose to avoid undesired effects. Do not stop the use of this medicine without consulting your doctor.

Use in children

Doloneuron NT 100 Tablet is not recommended in children under 18 years of age as the safety and efficacy data are not clinically established.

Use in the elderly

Doloneuron NT 100 Tablet should be used with extreme caution in the elderly due to the increased risk of side effects. Hence consult your doctor for further guidance.

Sexual problems

Doloneuron NT 100 Tablet should be used with caution as it may cause decreased sexual desire, erectile dysfunction (inability to develop or maintain an erection during sexual activity), etc. If you experience these problems, consult your doctor for further guidance.

Liver conditions

Doloneuron NT 100 Tablet is broken down in the liver. Hence it should be used with caution if you have liver problems as it may cause further liver impairment. Your doctor may suggest tests to monitor the liver functions and recommend dose adjustments, if necessary, based on your clinical condition.

Surgery

Inform your doctor about the use of Doloneuron NT 100 Tablet before undergoing surgery, as it can affect the functioning of your heart which is not ideal in surgeries.

Missed Dose

Do not miss the dose of Doloneuron NT 100 Tablet. In case you miss a dose, take it as soon as you remember. If it is time for the next scheduled dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Do not take more than the recommended dose of Doloneuron NT 100 Tablet. Seek emergency medical treatment in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with Doloneuron NT 100 Tablet as it may increase the risk of side effects like dizziness, drowsiness, and difficulty in concentration.
Interaction with Medicine

Morphine

Fosphenytoin

Aripiprazole

Ondansetron

Cetirizine

Disease interactions

Kidney diseases

Doloneuron NT 100 Tablet should be used with caution if you have kidney problems due to the increased risk of side effects. Your doctor may suggest tests to monitor your kidney function during treatment with this medicine and recommend appropriate dose adjustment or an alternative medicine based on your clinical condition.

Heart Disease

Doloneuron NT 100 Tablet should be used with extreme caution if you have heart problems due to the risk of altered blood pressure levels, irregular heart rate, and other heart-related abnormalities. Your doctor may monitor your heart function while on treatment with this medicine.

Phaeochromocytoma

Phaeochromocytoma is a rare tumour of the adrenal glands (an organ located above the kidneys). The tumour releases hormones that may cause high blood pressure, headache, sweating, etc. Doloneuron NT 100 Tablet should be used with caution if you have phaeochromocytoma as it can cause a severe increase in your blood pressure.

Diabetes Mellitus

Diabetes refers to high blood sugar levels. Doloneuron NT 100 Tablet should be used with caution if you have diabetes as it can cause an alteration in blood sugar level. Hence monitor your blood sugar levels regularly while taking this medicine.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Doloneuron NT 100 Tablet with or without food as instructed by your doctor. Take the medicine with a sufficient amount of water. Ensure that the correct dose of medicine is taken for the prescribed duration to avoid undesired effects. Do not stop taking this medicine without consulting your doctor, as it may cause withdrawal symptoms like nausea, headache, irritability, mood changes, etc. Consult the doctor if you experience any undesirable effects that persist or worsen. Doloneuron NT 100 Tablet may cause weight gain, so it is important to exercise regularly and eat a healthy diet to maintain your weight.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Causes sleepiness

How it works
Doloneuron NT 100 Tablet is composed of Gabapentin and Nortriptyline. Gabapentin alters the activity of certain chemicals in the brain, thus helping to prevent the transmission of pain signals to the brain. Nortriptyline also acts on your central nervous system (the brain and the spinal cord) and prevents the transfer of pain signals in the brain.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Gamma-aminobutyric acid analogs, Tricyclic antidepressants

Schedule

Schedule H

Accessdata.fda.gov. 2022. [online] Available at: [Accessed 21 July 2022].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/020235s064_020882s047_021129s046lbl.pdf

Medicines.org.uk. 2022. [online] Available at: [Accessed 21 July 2022].

https://www.medicines.org.uk/emc/files/pil.158.pdf

Drugs, H., 2022. Nortriptyline: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: [Accessed 21 July 2022].

https://medlineplus.gov/druginfo/meds/a682620.html
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Information on this page was last updated on 28 Jul 2022

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