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Diurix 1.5 mg Tablet Sr

Manufactured by: Bal Pharma Ltd.
Composition: Indapamide
Prescription Required: Yes
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Description

Diurix 1.5 mg Tablet Sr is a diuretic used to reduce high blood pressure as well as edema (swelling) and fluid retention caused by heart diseases. It should be used with caution in patients with severe kidney diseases due to the increased risk of severe side effects. Frequent monitoring of blood pressure and electrolytes level is necessary while taking this medicine.

Side effects

Major & minor side effects for Diurix 1.5 mg Tablet Sr

  • Increased urinationsevere
  • Dry mouthsevere
  • Hypotensionsevere
  • Itching or rashsevere
  • Abdominal pain
  • Dizzinesssevere
  • Headachesevere
  • Joint pain, stiffness, and swelling
  • Muscle cramps
  • Loss of appetite
  • Nausea and vomiting
  • Irregular heartbeatsevere
SEVERE
Contact your doctor immediately if any of these symptoms are experienced on a regular basis.
RARE
Observed in a small fraction of population.
This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

Highlights

Commonly asked questions for Diurix 1.5 mg Tablet Sr

Onset of action

The effect of this medicine can be observed in 1 to 3 hours after oral administration.

Duration of effect

The effect of this medicine lasts for an average duration of 8 to 12 hours.

Safe with alcohol?

moderate
Consumption of alcohol is not recommended while you are taking this medicine. The combination may increase the risk of dizziness, fainting, and very low blood pressure. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine. Report any incidence of breathing difficulty or dizziness to the doctor immediately.

Is it habit forming?

No habit-forming tendency has been reported.

Usage in pregnancy?

This medicine is recommended for use in pregnant women only when necessary. Discuss all the risks and benefits with your doctor before taking this medicine.

Usage while breast-feeding?

This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Substitutes

List of substitutes for Diurix 1.5 mg Tablet Sr

Below is the list of medicines, which have the same composition, strength and form as Diurix 1.5 mg Tablet Sr, and hence can be used as its substitute.
Indap 1.5 mg Tablet Sr
Orchid Chemicals & Pharmaceuticals Ltd.
Inditor 1.5 mg Tablet Sr
Ipca Laboratories Pvt. Ltd.
Lorvas 1.5 mg Tablet Sr
Torrent Pharmaceuticals Ltd.
Natritor 1.5 mg Tablet Sr
Ipca Laboratories Pvt. Ltd.

What is it prescribed for?

Uses of Diurix 1.5 mg Tablet Sr

  • Edema

    This medicine is used to reduce the swelling due to fluid accumulation in the hands, feet, and ankles associated with heart diseases.
  • Hypertension

    This medicine is used to reduce high blood pressure caused by fluid overload and genetic or environmental factors.

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When not to use?

Contraindications of Diurix 1.5 mg Tablet Sr

  • Allergy

    This medicine is not recommended for use in patients with a known allergy to indapamide.
  • Anuria

    This medicine is not recommended for use in patients with anuria (a condition where the kidney is unable to produce urine) due to the increased risk of severe side effects.

Dosage

  • Missed Dose

    If a dose of Diurix 1.5 mg Tablet Sr is missed, take the dose as soon as you remember it. If it is almost time for the next dose, skip the missed dose and take the next dose. Do not double the dose to make up for the missed one.
  • Overdose

    Seek emergency medical treatment or contact the doctor in case of an overdose.

Interactions

All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcoholmoderate

  • Description

    - N/A
  • Instructions

    - Consumption of alcohol is not recommended while you are taking this medicine. The combination may increase the risk of dizziness, fainting, and very low blood pressure. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine. Report any incidence of breathing difficulty or dizziness to the doctor immediately.

Interaction with Medicine

  • Amitriptylinemoderate
  • Cisapridesevere
  • Lithiumsevere
  • Amiodaronesevere
  • Insulinmoderate
  • Nonsteroidal anti-inflammatory medicinesmoderate

Disease interactions

  • Asthma

    moderate
    This medicine should be used with caution in patients with bronchial asthma due to the increased risk of sensitivity reactions. An alternative treatment option should be considered based on the clinical condition.
  • Diabetes

    moderate
    This medicine should be used with caution in patients with diabetes due to the increased risk of hypoglycemia. Close monitoring of blood glucose levels is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.
  • Hyperlipidemia

    moderate
    This medicine should be used with caution in patients with hyperlipidemia since it may further increase the blood triglycerides and cholesterol levels. Close monitoring of blood triglycerides and cholesterol levels is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.
  • Hyperparathyroidism

    moderate
    This medicine should be used with caution in patients with hyperparathyroidism due to the increased risk of worsening of the patient's condition. Close monitoring of blood calcium levels is recommended for such patients. Replacement with a suitable alternative may be required based on the clinical condition.
  • Hyperuricemia

    moderate
    This medicine should be used with caution in patients with hyperuricemia due to the increased risk of worsening of the patient's condition. Close monitoring of uric acid levels is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Food interactions

  • Information not available.

Lab interactions

  • Thyroid function tests

    moderate
    This medicine may decrease the serum protein-bound iodine levels. This factor should be taken into account when interpreting thyroid function tests' results. It is advised that you inform the doctor about all your current medicines including herbs and supplements before undergoing thyroid function tests.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.

General Instructions

Take Diurix 1.5 mg Tablet Sr as advised by your doctor. Do not take in larger or smaller amounts than prescribed. Take this medicine at daytime to prevent sleep disturbance. Drink an adequate amount of water. Monitoring of kidney function and electrolytes levels is necessary while taking this medicine. Ensure that the course of treatment is completed. Report any adverse effects to the doctor on priority.

Warnings

Warnings for special population

  • Pregnancy

    - This medicine is recommended for use in pregnant women only when necessary. Discuss all the risks and benefits with your doctor before taking this medicine.
  • Breast-feeding

    - This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

General warnings

  • Hepatic dysfunction

    - Diurix 1.5 mg Tablet Sr should be used with extreme caution in patients suffering from liver diseases due to an increase in the risk of serious adverse effects including coma. Close monitoring of liver function is advised while taking this medicine. Report any symptoms of confusion or jaundice to the doctor on priority. Therapy with the medicine may need to be discontinued based on the clinical condition.
  • Renal disease

    - Diurix 1.5 mg Tablet Sr may cause Azotemia in patients with a known history of a severe renal disease. Close monitoring of kidney function is necessary while taking this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
  • Volume and electrolyte depletion

    - Diurix 1.5 mg Tablet Sr may alter the blood volume levels and electrolytes levels. This may cause dizziness, dry mouth, and acid-base imbalance. Close monitoring of blood pressure and electrolytes levels is necessary while taking this medicine. Report any symptoms such as weakness, lethargy, muscle pain, drowsiness, dizziness, irregular heartbeat, etc. to the doctor immediately. Appropriate corrective measures and dose adjustments may be required based on the clinical condition of the patient.
  • Lupus Erythematosus

    - Diurix 1.5 mg Tablet Sr should be used with caution in patients with lupus erythematosus due to the increased risk of worsening of the patient's condition. Replacement with a suitable alternative should be considered based on the clinical condition of the patient.

Other details

  • Can be taken with or without food, as advised by your doctor
  • To be taken as instructed by doctor
  • May cause sleepiness

How it works

Diurix 1.5 mg Tablet Sr works by increasing the excretion of water and sodium from the kidneys. This helps in bringing down the blood pressure as well as swelling.

Legal Status

Approved
Approved
Approved
Approved

Classification

Category
Thiazide diuretics
Schedule
Schedule H

References

  • [Internet]. 2017 [cited 21 August 2017]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/018538s028lbl.pdf
  • [Internet]. Toxnet.nlm.nih.gov. 2017 [cited 21 August 2017]. Available from: https://toxnet.nlm.nih.gov/cgi-bin/sis/search2
  • DailyMed - Indapamide tablet [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 21 August 2017]. Available from: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=788ebfde-39a2-42a4-9bd6-34ad87f66a97
  • Indapamide - DrugBank [Internet]. Drugbank.ca. 2017 [cited 21 August 2017]. Available from: https://www.drugbank.ca/drugs/DB00808
  • Indapamide: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 21 August 2017]. Available from: https://medlineplus.gov/druginfo/meds/a684062.html
  • Prescribing medicines in pregnancy database [Internet]. Therapeutic Goods Administration (TGA). 2017 [cited 21 August 2017]. Available from: http://www.tga.gov.au/prescribing-medicines-pregnancy-database

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Information on this page was last updated on 4 Sep 2017

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We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.