Disodium Hydrogen Citrate
Description
Disodium Hydrogen Citrate is a medicine that contains Disodium hydrogen citrate. It is mainly used for the treatment of urinary tract infections, painful or difficult urination, kidney stones, urinary acidosis and gout. Disodium Hydrogen Citrate works by removing excess uric acid from the blood through urine.
Disodium Hydrogen Citrate shows some side effects like diarrhoea, nausea, stomach pain, vomiting, increased urination and tiredness. If any of these symptoms do not resolve with time or worsen, consult your doctor for a dose adjustment or alternative treatment. The most common side effect of Disodium Hydrogen Citrate is stomach pain, inform your doctor if it stays for a long duration.
Disodium Hydrogen Citrate is usually taken after a meal with plenty of water or as prescribed by your doctor. The effect of this medicine can be seen quickly. Disodium Hydrogen Citrate is not recommended for use in pregnant and breastfeeding women as there is not enough safety and efficacy data available. It is also not recommended in people with severe kidney impairment.
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Side effects
Major & minor side effects for Disodium Hydrogen Citrate
- Diarrhoea
- Nausea and vomiting
- Tiredness
- Frequent urge to urinate
- Unpleasant taste
- Stomach cramps
- Excessive air or gas in stomach
- Change in mood
Uses of Disodium Hydrogen Citrate
What is it prescribed for?
- Kidney stones
- Urinary tract infection
- Painful urination
- Gout
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Concerns
Commonly asked questions
- Onset of actionThe exact amount of time required for Disodium Hydrogen Citrate to show its action is not known. However, due to its simple mechanism of action, it starts working within few minutes after intake.
- Duration of effectThe amount of time for which Disodium Hydrogen Citrate remains active in the body is 4-6 hours.
- Safe with alcohol?Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
- Is it habit forming?No habit-forming tendencies were reported for Disodium Hydrogen Citrate.
- Usage in pregnancy?Disodium Hydrogen Citrate is not recommended for use during pregnancy as no sufficient data is available to understand its effect on the safety of your foetus. Your doctor prescribes this medicine only if possible benefits outweigh the risks.
- Usage while breast-feeding?Disodium Hydrogen Citrate is not recommended for use in breastfeeding women unless necessary since there is no exact data available to understand its effect on the safety of your infant. Discuss with your doctor all the risks and benefits associated with it before taking this medicine.
Allergy
Avoid taking Disodium Hydrogen Citrate if you are allergic to it. Inform your doctor if there is any history of allergy to fexofenadine. If you notice any symptoms such as skin rash, itching/swelling, dizziness, breathing difficulties, etc. inform your doctor and seek immediate medical attention
Hyperkalaemia
Hyperkalaemia is a condition in which there are high potassium levels in the blood. Potassium is critical to the functioning of nerve and muscle cells, including those in your heart. Disodium Hydrogen Citrate is not recommended for use if you are with hyperkalaemia due to the increased risk of severe side effects.
Severe kidney disease
Disodium Hydrogen Citrate is not recommended for use if you have severe kidney impairment due to the risk of worsening the condition. Consult your doctor before taking this medication.
Warnings for special population
Pregnancy
Disodium Hydrogen Citrate is not recommended for use during pregnancy as no sufficient data is available to understand its effect on the safety of your foetus. Your doctor prescribes this medicine only if possible benefits outweigh the risks.
Breast-feeding
Disodium Hydrogen Citrate is not recommended for use in breastfeeding women unless necessary since there is no exact data available to understand its effect on the safety of your infant. Discuss with your doctor all the risks and benefits associated with it before taking this medicine.
General warnings
Stomach disorders
Disodium Hydrogen Citrate should be used with extreme caution if you have stomach disorders, due to the risk of having a colonic perforation (hole in the large intestine). Your clinical condition needs to be closely monitored while receiving this medicine. You should ask your doctor for appropriate dose adjustments or alternate medicine if required.
Liver impairment
Disodium Hydrogen Citrate should be used with caution if you have liver impairment as this medicine is broken down in the liver that can increase the risk of worsening your condition. Your clinical condition needs to be closely monitored while receiving this medicine. You should ask your doctor for appropriate dose adjustments or alternate medicine if required.
Dehydration
Disodium Hydrogen Citrate should be used with extreme caution in acute dehydration as alkalinizing agents containing sodium can change the water balance in your body. Your clinical condition needs to be closely monitored while receiving this medicine. You should ask your doctor for appropriate dose adjustments or alternate medicine if required.
Other medicines
Disodium Hydrogen Citrate may interact with many other medicines and may cause severe side effects. Hence, it is advised that inform your doctor about the current medicines you are using including herbs and supplements, before starting treatment with this medicine.
Missed Dose
If you have missed a dose of Disodium Hydrogen Citrate then take the missed dose as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose. Do not double your dose to make up for the missed one.
Overdose
If you have consumed more than the prescribed dose of Disodium Hydrogen Citrate then seek emergency medical treatment or contact the doctor immediately.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Instructions
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Tetracyclines
Methotrexate
Barbiturates
Disease interactions
Kidney disease
Disodium Hydrogen Citrate should be administered with extreme caution if you have compromised kidney function as it changes the acid-base balance of the system, which affects the functioning of your kidneys. Your kidney function, acid/base balance and electrolytes should be monitored while receiving this medicine. Your doctor may adjust the dose or prescribe some alternative based on your condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Disodium Hydrogen Citrate exactly as prescribed by the doctor. Do not take in larger or smaller quantities than prescribed. Take plenty of water while taking this medicine.
Shake the bottle well before measuring the dose. Follow all the usage instructions mentioned on the label.
Avoid foods like beets, chocolate, spinach, rhubarb, tea, and most nuts (which are rich in oxalate), which can contribute to kidney stones when taking Disodium Hydrogen Citrate.
Do not stop the use of Disodium Hydrogen Citrate without consulting your doctor. Inform your doctor if you experience any undesirable side effects.
Miscelleneous
How it works
Acidic urine is more prone to bacterial infections. Disodium Hydrogen Citrate makes your urine more alkaline by removing excess uric acid in the blood and urine and reduces the chances of urinary tract infection by inhibiting the growth of bacteria in the tract. It helps your kidneys to get rid of excess uric acid, thereby prevents gout and kidney stones.
Legal Status
Classification
Category
Alkalizers, Urinary pH modifiers
Schedule
Schedule H
Vibcare Pharma. 2021. Disodium Hydrogen Citrate | VIBTRAL - Vibcare Pharma. [online] Available at: < [Accessed 4 August 2021].
Pubchem.ncbi.nlm.nih.gov. 2021. Disodium citrate. [online] Available at: < [Accessed 4 August 2021].
Drugs.ncats.io. 2021. NCATS Inxight: Drugs — DISODIUM HYDROGEN CITRATE. [online] Available at: < [Accessed 4 August 2021].
Labeling.pfizer.com. 2021. [online] Available at: < [Accessed 10 August 2021].
Information on this page was last updated on 7 Oct 2021
Disclaimer
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