Dipyridamole

Description

Dipyridamole is used to reduce the risk of blood clots after a heart valve replacement. It may also be used for the prevention of stroke caused by a blood clot formed in the brain.

Side effects

Major & minor side effects for Dipyridamole

  • Dizziness
  • Stomach pain
  • Headache
  • Skin rash and itching
  • Nausea or vomiting
  • Unusual warmth of skin
  • Unusual bleeding or bruising
  • Yellowing of skin or eyes
  • Chest pain and discomfort
  • Unusual tiredness or weakness
  • Joint pain, stiffness, and swelling
  • Hair loss

Uses of Dipyridamole

What is it prescribed for?

  • Thromboembolism prophylaxis
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Concerns

Commonly asked questions

  • Onset of action
    The effect of this medicine can be observed within 30 minutes of administration of the dose.
  • Duration of effect
    The effect of this medicine lasts for an average duration of 3 hours.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to dipyridamole or any other inactive ingredients present along with it.

Thrombocytopenia

This medicine is not recommended for use in patients with thrombocytopenia due to the increased risk of worsening of the patient’s condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Other medicines

Dipyridamole may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Use in children

This medicine is not recommended for use in children less than 12 years of age since the safety and efficacy of use are not clinically established. It is also not recommended for use in patients less than 18 years of age unless specifically prescribed by your pediatrician after evaluating all the potential risks and benefits.

Liver diseases

This medicine should be used with caution in patients with liver diseases due to the increased risk of severe adverse effects. Regular monitoring of liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Coronary artery disease

This medicine should be used with caution in patients with coronary artery disease, which is characterized by hardening of the blood vessel, due to the increased risk of worsening of the patient’s condition. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Hypotension (low blood pressure levels)

This medicine should be used with caution in patients suffering from low blood pressure levels due to the increased risk of severe adverse effects. Close monitoring of clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the patient's condition.

Heart diseases

This medicine should be used with caution in patients suffering from heart-related complications like angina, heart failure, heart attack, etc. It should also be used with caution in patients at risk of heart diseases. Close monitoring of clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be necessary in some cases based on the patient's condition.

Myasthenia gravis

This medicine should be used with caution in patients with myasthenia gravis, which is characterized by weakness and rapid tiring of muscles, due to the increased risk of worsening of the patient’s condition. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Migraine

This medicine should be used with caution in patients suffering from migraine since the risk of worsening of symptoms is significantly high. An alternative treatment may be necessary in some cases based on the clinical condition.

Driving or Operating machinery

Use of this medicine may cause dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience dizziness during treatment with this medicine.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for the next scheduled dose, then the missed dose can be skipped. Do not double the dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Escitalopram

Dalteparin

Aminophylline

Prasugrel

Warfarin

Ibuprofen

Fondaparinux

Diclofenac

Adenosine

Caffeine

Disease interactions

Disease

Information not available.
Food interactions
Avoid or limit the uptake of garlic or garlic-containing products with this medicine due to the increased risk of excessive bleeding. Contact your doctor immediately if symptoms of bleeding like dizziness, lightheadedness, red or black and tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, weakness etc. are experienced.
Avoid or limit the uptake of ginger or ginger-containing products with this medicine due to the increased risk of excessive bleeding. Contact your doctor immediately if symptoms of bleeding like dizziness, lightheadedness, red or black and tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, weakness, etc. are experienced.
Lab interactions
Information not available.
Take this medicine exactly as prescribed by the doctor. Do not take in larger or smaller quantities than recommended. This medicine is normally given in a combination and hence it is recommended to use all medicines in the manner advised by the doctor for appropriate treatment. Ensure that the course of treatment is completed. Do not stop the use of any medicine without consulting your doctor.
Miscelleneous

To be taken before food

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by preventing the formation of blood clots.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Platelet aggregation inhibitors

Schedule

Schedule H

[Internet]. Medicines.org.uk. 2018 [cited 27 September 2018]. Available from:

https://www.medicines.org.uk/emc/files/pil.4550.pdf

DailyMed - Dipyridamole tablet [Internet]. Dailymed.nlm.nih.gov. 2018 [cited 27 September 2018]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=312aadb1-435c-4aa7-8e46-6506cedacaa0&audience=consumer

Dipyridamole [Internet]. Pubchem.ncbi.nlm.nih.gov. 2018 [cited 27 September 2018]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/dipyridamole#section=Top

Dipyridamole - DrugBank [Internet]. Drugbank.ca. 2018 [cited 27 September 2018]. Available from:

https://www.drugbank.ca/drugs/DB00975

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Information on this page was last updated on 25 Jan 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.