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Dinost Gel
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Dinost Gel

Manufactured byNEON LABORATORIES LTD
ContainsDinoprostone
Description
Dinost Gel is a uterotonic medication (a medicine that stimulates uterine muscles). It is used to help prepare your cervix (the lower opening of the uterus/womb) for labour and delivery. It is used for women who are having a normal pregnancy and who are near their delivery due date. Dinost Gel may cause some common side effects such as nausea, vomiting, diarrhoea, abdominal cramps (painful muscle contractions), etc. However, your doctor will provide appropriate treatment based on the severity of your symptoms. Dinost Gel is administered by your doctor in a clinic or hospital setting. Your doctor will continuously monitor your uterine activity and the heart rate of your foetus after the administration of this medicine. Dinost Gel should be avoided if you are allergic to it. Inform your doctor if you have a history of asthma, glaucoma (increased fluid pressure in your eye) or any pre-existing heart/liver/kidney problems before receiving this medicine. Dinost Gel is only recommended for normal/vaginal delivery and not for caesarean delivery. If you are breastfeeding, consult your doctor.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Dinost Gel

  • Nausea and vomiting
  • Diarrhoea
  • Abdominal cramps
  • Fever
  • Constipation
  • Swelling of genital area
  • Chills or shivering
  • Headache

Uses of Dinost Gel

What is it prescribed for?

  • Induction of labour
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    Dinost Gel shows its effect in 30-45 minutes.
  • How long do the effects of this medicine last?
    The time for which Dinost Gel will remain active in your body is not clinically known.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies have been reported with Dinost Gel.
  • Can this medicine be taken during pregnancy?
    Use of Dinost Gel is not recommended for pregnant women other than for the indicated uses such as the induction of labour and termination of pregnancy.
  • Can this medicine be taken while breast-feeding?
    Dinost Gel is excreted into breastmilk. When used for induction of labour, the presence of this medicine in breastmilk will not affect your baby and you may breastfeed normally after delivery.

Allergy

Avoid receiving Dinost Gel if you are allergic to it. However, seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.

Caesarean section

Caesarean section, also known as C-section/caesarean delivery, is the surgical procedure by which your baby is delivered through an incision (cut) in your abdomen. Dinost Gel is not recommended if have a history of caesarean section due to the increased risk of complications during the delivery process.

Pelvic Inflammatory Disease

Pelvic inflammatory disease is the infection of the reproductive organs in women. Symptoms may include fever, pain in your lower abdomen, vaginal discharge, painful/frequent urination, etc. Dinost Gel is not recommended for use if you are currently infected with/have a history of pelvic inflammatory disease due to the increased risk of worsening your condition.

Placenta praevia

Placenta praevia is a condition in which your placenta partially or completely blocks the neck of the uterus (womb) and interferes with the normal/vaginal delivery of your baby. The main symptom includes vaginal bleeding during pregnancy and delivery. Since caesarean section/c-section is recommended in such cases, the use of Dinost Gel is not recommended.

Pregnancy complications

Cephalopelvic disproportion and fetal malpresentation are pregnancy complications where the foetus is positioned in a manner where the delivery of the baby becomes complicated. Dinost Gel is not recommended in such cases.
Warnings for special population

Pregnancy

Use of Dinost Gel is not recommended for pregnant women other than for the indicated uses such as the induction of labour and termination of pregnancy.

Breast-feeding

Dinost Gel is excreted into breastmilk. When used for induction of labour, the presence of this medicine in breastmilk will not affect your baby and you may breastfeed normally after delivery.
General warnings

Other diseases

Dinost Gel should be used with caution if you have a history of epilepsy (fits), heart/liver/kidney problems due to the increased risk of worsening your condition.

Uterine rupture

Dinost Gel has been associated with an increased risk of uterine rupture when used for labour induction in some women. Continuous electronic monitoring of uterine activity and foetal heart rate is recommended while using this medicine.

For hospital use only

Dinost Gel should be administered only by a trained obstetrician in a hospital setting with appropriate medical care facilities.

Use with caution

Dinost Gel should be used with caution in women aged 35 years or older, with a gestational age over 40 weeks, and those with pregnancy-related complications due to the increased risk of bleeding.

Missed Dose

Since Dinost Gel is administered by a qualified healthcare professional in the clinical or hospital setting, the likelihood of a missed dose is very low.

Overdose

Since Dinost Gel is administered in a hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Misoprostol

Mifepristone

Oxytocin

Ergonovine

Disease interactions

Asthma

Dinost Gel should be used with caution if you have a history of asthma due to the increased risk of worsening your condition.

Hypotension

Hypotension is a condition of low blood pressure. Dinost Gel should be used with caution if you have hypotension due to the increased risk of side effects.

Glaucoma

Glaucoma is a condition with high intraocular pressure (fluid pressure inside your eye). Dinost Gel should be used with caution if you have a history of glaucoma due to the increased risk of side effects.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Dinost Gel should be administered only by a trained obstetrician in a hospital setting with appropriate medical care facilities. Dinost Gel is administered intravaginally by your doctor. It is recommended to stay in the supine position (lying down position with your face facing upwards) 15 to 30 minutes following administration.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works
Dinost Gel is similar to prostaglandin, the hormone that helps to relax the muscles of the cervix (opening of the uterus) for inducing labour in pregnant women who are at the end of pregnancy, ready to deliver the baby.
Legal Status

Approved

Approved

Unknown

Approved

Classification

Category

Uterotonic agents

Schedule

Schedule H

Drugs, H., 2021. Dinoprostone: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 18 September 2021].

https://medlineplus.gov/druginfo/meds/a682512.html>

Dailymed.nlm.nih.gov. 2021. DailyMed - PREPIDIL- dinoprostone gel. [online] Available at: < [Accessed 18 September 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ab03de5b-782c-4f81-a8dc-7ef9969dd0cf>

Medicines.org.uk. 2021. Prostin E2 Vaginal Gel 2mg - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 18 September 2021].

https://www.medicines.org.uk/emc/product/1090/smpc>

Medicines.org.uk. 2021. [online] Available at: < [Accessed 18 September 2021].

https://www.medicines.org.uk/emc/files/pil.1090.pdf>
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Information on this page was last updated on 19 Oct 2021

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