Dienogest

Description

Dienogest is a progestogen used in the treatment of endometriosis. This medicine is also used in a combination with ethinyl estradiol for contraception. It is not recommended for use in patients suffering from severe liver function impairment due to the increased risk of worsening of the patient's condition.

Side effects

Major & minor side effects for Dienogest

  • Headache
  • Breast discomfort
  • Depressed mood
  • Acne
  • Weight gain
  • Nausea
  • Vomiting
  • Back pain
  • Hair loss

Uses of Dienogest

What is it prescribed for?

  • Endometriosis
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Concerns

Commonly asked questions

  • Onset of action
    The peak effect of this medicine can be observed within 1.5 to 2 hours of administration of the dose.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women since there is no need to treat endometriosis during pregnancy. However, your doctor may prescribe this medicine in certain specific situations based on your clinical condition. Discuss all the risks and benefits with your doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue the drug or to discontinue breastfeeding based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to dienogest or any other inactive ingredients present along with it.

Active venous thromboembolic disorder

This medicine is not recommended for use in patients suffering from an active venous thromboembolic disorder due to the increased risk of worsening of the patient's condition.

Severe Hepatic impairment

This medicine is not recommended for use in patients suffering from a severe impairment of liver function due to the increased risk of worsening of the patient's condition.

Liver Tumours

This medicine is not recommended for use in patients with a known history of liver tumors due to the increased risk of worsening of the patient's condition.

Undiagnosed vaginal bleeding

This medicine is not recommended for use in patients suffering from an undiagnosed vaginal bleeding due to the increased risk of worsening of the patient's condition.

Cardiovascular Disease

This medicine is not recommended for use in patients with a history of cardiovascular diseases such as a heart attack (myocardial infarction), stroke, ischemic heart disease, etc. due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women since there is no need to treat endometriosis during pregnancy. However, your doctor may prescribe this medicine in certain specific situations based on your clinical condition. Discuss all the risks and benefits with your doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue the drug or to discontinue breastfeeding based on your clinical condition.
General warnings

Circulatory Disorders

This medicine should be used with caution in patients suffering from circulatory disorders since it may increase the risk of severe adverse effects. Close monitoring of clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Osteoporosis

This medicine should be used with extreme caution in patients suffering from osteoporosis due to the increased risk of worsening of the patient's condition. Regular monitoring of serum calcium levels, as well as bone mineral density, may be necessary while receiving this medicine. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Depression

This medicine should be used with extreme caution in patients suffering from depression due to the increased risk of worsening of the patient's condition. Close monitoring of the patient for any changes in mood or behavior is recommended. Appropriate caregiver/patient counseling, dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Use in children

This medicine is not recommended for use in patients less than 12 years of age and in patients prior to menarche (first menstrual bleeding) since the safety and efficacy of use are not clinically established.

Missed Dose

The missed dose should be taken as soon as possible. It is advisable to skip the missed dose if it is already time for your next scheduled dose. Do not use extra medicine to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

CYP3A4 inhibitors

HIV protease inhibitors

Disease interactions

Hepatic impairment

This medicine should be used with extreme caution in patients with mild-to-moderate liver diseases due to the increased risk of severe adverse effects. Regular monitoring of liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Diabetes Mellitus

This medicine should be used with caution in patients suffering from diabetes mellitus due to the increased risk of altered blood glucose levels. Close monitoring of blood glucose levels is recommended for these patients. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine with or without food, as prescribed by the doctor. Do not take/administer in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Does not cause sleepiness

How it works
This medicine reduces the symptoms such as pain and menstrual irregularities associated with endometriosis.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Progestins

Schedule

Schedule H

[Internet]. Mri.cts-mrp.eu. 2018 [cited 30 July 2018]. Available from:

http://mri.cts-mrp.eu/download/NL_H_1569_001_FinalSPC.pdf

[Internet]. Bayerresources.com.au. 2018 [cited 30 July 2018]. Available from:

http://www.bayerresources.com.au/resources/uploads/pi/file10142.pdf

Dienogest - DrugBank [Internet]. Drugbank.ca. 2018 [cited 30 July 2018]. Available from:

https://www.drugbank.ca/drugs/DB09123

TGA eBS - Product and Consumer Medicine Information Licence [Internet]. Ebs.tga.gov.au. 2018 [cited 30 July 2018]. Available from:

https://www.ebs.tga.gov.au/ebs/picmi/picmirepository.nsf/pdf?OpenAgent&id=CP-2010-PI-04227-3

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Information on this page was last updated on 27 Aug 2018

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.