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Dicloplus 50/350 Tablet
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Dicloplus 50/350 Tablet

Manufactured byHINDUSTAN ANTIBIOTICS LTD
ContainsDiclofenac (50 mg) + Paracetamol (350 mg)
Description
Dicloplus 50/350 Tablet is a combination of Diclofenac and Paracetamol. It is used to relieve pain and swelling in conditions like muscle pain, joint pain, tooth pain, ankylosing spondylitis (pain due to the fusing of bones in the spine), osteoarthritis (pain on movement due to wearing of the protective covering at the ends of the bones) and rheumatoid arthritis (caused when the body's immunity attacks the joints and damages it, resulting in pain, swelling and stiffness in joints). Dicloplus 50/350 Tablet causes side effects like nausea, vomiting, heartburn, stomach pain, loss of appetite, and diarrhoea. Avoid this medicine if you are allergic to it. This medicine may cause dizziness and drowsiness. Therefore, avoid driving or operating machines if you feel drowsy or dizzy after taking this medicine. Dicloplus 50/350 Tablet can be taken with food, milk, or an antacid (that your doctor may prescribe) to avoid stomach irritation. For the ease of remembering, take it at around the same time every day. Do not self-medicate or use it beyond the prescribed duration. Dicloplus 50/350 Tablet has to be used with caution if you have a history of stomach or intestinal bleeding, heart problems, asthma, and severe liver and kidney problems. Inform your doctor about any medical condition that you are undergoing or any medications you take. This medicine may affect the development of your foetus. Consult your doctor if you are pregnant, planning a pregnancy or are breastfeeding.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Dicloplus 50/350 Tablet

  • Stomach pain
  • Diarrhoea
  • Skin rash
  • Ringing or buzzing in the ears
  • Nausea and Vomiting
  • Dark or clay coloured stools
  • Tiredness
  • Loose stools
  • Bloody and cloudy urine

Uses of Dicloplus 50/350 Tablet

What is it prescribed for?

  • Rheumatoid Arthritis
  • Osteoarthritis
  • Ankylosing Spondylitis
  • Mild to moderate pain
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    Dicloplus 50/350 Tablet starts showing its action within 1 hour of taking it.
  • How long do the effects of this medicine last?
    Dicloplus 50/350 Tablet lasts for an average duration of 10-12 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended while taking Dicloplus 50/350 Tablet since it may increase the risk of side effects like confusion, dizziness, and impaired judgment, and stomach bleeding.
  • Is this a habit forming medicine?
    Dicloplus 50/350 Tablet has no habit-forming tendency.
  • Can this medicine be taken during pregnancy?
    Dicloplus 50/350 Tablet is not recommended during pregnancy due to the risk of harmful effects on your foetus. Inform your doctor if you are pregnant while taking it. Use this medicine in pregnancy only if your doctor prescribes it.
  • Can this medicine be taken while breast-feeding?
    Dicloplus 50/350 Tablet is not recommended if you are breastfeeding. If required it should only be used upon your doctor's recommendation.

Allergy

Avoid using Dicloplus 50/350 Tablet if you have a known allergy to this medicine. Seek medical attention if you encounter any allergic reactions such as a skin rash, hives (itchy, painful eruptions that sting), swelling (face, lips, tongue, etc.), breathing difficulty, etc.

Kidney failure

Dicloplus 50/350 Tablet is not recommended for use in people with severe kidney problems associated with excessive painkillers. If you have pre-existing kidney problems, consult your doctor before taking the medicine.

Severe liver disease

Dicloplus 50/350 Tablet is absorbed and broken down and absorbed in your liver. This medicine is not recommended if you already have severe liver problems as it may cause further damage to your liver.

Stomach and intestinal bleeding

Dicloplus 50/350 Tablet is not recommended if you have stomach ulcers or stomach and intestinal bleeding as it may worsen your condition.

Coronary Artery Bypass Surgery (CABG)

Coronary Artery Bypass Surgery (CABG) is a surgical procedure to restore normal blood flow to the heart. Do not use Dicloplus 50/350 Tablet to relieve pain after heart surgery as it may cause severe side effects.
Warnings for special population

Pregnancy

Dicloplus 50/350 Tablet is not recommended during pregnancy due to the risk of harmful effects on your foetus. Inform your doctor if you are pregnant while taking it. Use this medicine in pregnancy only if your doctor prescribes it.

Breast-feeding

Dicloplus 50/350 Tablet is not recommended if you are breastfeeding. If required it should only be used upon your doctor's recommendation.
General warnings

Skin rash

Dicloplus 50/350 Tablet may cause skin allergies without any warnings. Immediately report any signs and symptoms like rashes, hives (painful eruptions that itch and sting), or other allergic symptoms. Discontinue the treatment and seek further guidance from your doctor.

Water retention and oedema

Dicloplus 50/350 Tablet may cause oedema (accumulation of water and fluids in your body's tissue) in some people. This medicine has to be taken with caution if you have any medical condition related to your heart and kidney, high blood pressure or if you are taking any other medicines that may affect your kidney. Your blood pressure, electrolyte levels, and heart and kidney function will be closely monitored by your doctor.

Liver problem

Dicloplus 50/350 Tablet is broken down and absorbed in your liver. If you have a pre-existing liver condition, inform your doctor before taking this medicine as it can cause further damage.

Kidney problem

Dicloplus 50/350 Tablet should be used with caution if you have kidney problems. Inform your doctor about your condition before taking this medicine.

Driving or operating a machine

Dicloplus 50/350 Tablet may cause sleepiness, blurred vision or dizziness in some people. If you experience such side effects, do not drive vehicles and operate machines after taking this medicine.

Missed Dose

If you have missed Dicloplus 50/350 Tablet at a scheduled time, take it as soon as you remember. However, if it is time for your next dose, skip the dose. Do not double the dose.

Overdose

Never take more than the prescribed dose. Contact your doctor in case you suspect an overdose of Dicloplus 50/350 Tablet.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended while taking Dicloplus 50/350 Tablet since it may increase the risk of side effects like confusion, dizziness, and impaired judgment, and stomach bleeding.
Interaction with Medicine

Carbamazepine

Methotrexate

Phenytoin

Ramipril

Sodium Nitrite

Apixaban

Aspirin

Disease interactions

Heart Disease

Long-term use of Dicloplus 50/350 Tablet may increase the risk of a heart attack in people with pre-existing heart conditions or heart failure. It should not be used to treat pain after coronary bypass surgery.

Asthma

Asthma is an allergic reaction causing narrowing and excess mucous secretion in the air pathway of your lungs leading to breathing difficulty. People with asthma may experience allergic reactions or the triggering of an asthmatic attack while taking Dicloplus 50/350 Tablet. Hence, it is not recommended for use in people with asthma, especially those who have a history of allergic reactions with the use of non-steroidal anti-inflammatory medicines (a type of painkillers).

Gastrointestinal toxicity

Long term use of Dicloplus 50/350 Tablet can cause damage to the stomach and intestine. Serious conditions like bleeding, ulceration and a hole in the linings of the stomach or intestinal wall may occur. If you experience chronic indigestion, the appearance of coffee coloured dry blood in stools or vomiting of blood, contact your doctor immediately as these symptoms are suggestive of gastrointestinal bleeding and ulceration.
Food interactions
Information not available.
Lab interactions

5-HIAA Urine Test

Dicloplus 50/350 Tablet can interfere with a urine test and may give a false-positive result. It is advised to inform your doctor and lab technician about all your current medicines before undergoing any lab test.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Dicloplus 50/350 Tablet with or after food to avoid an upset stomach. Do not break, crush or chew the tablet. Avoid self-medication and never take more than the prescribed dose. Never take this medicine for more than the prescribed duration. Take Dicloplus 50/350 Tablet at around the same time daily. Avoid alcohol consumption while taking this medicine as it may elevate dizziness or drowsiness and stomach bleeding. Do not drive or operate machines if you feel dizzy or drowsy.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works
Dicloplus 50/350 Tablet stops the release of a chemical called prostaglandins, which increases pain and swelling. Thus, this medicine provides pain relief and makes you feel better.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Non-steroidal anti-inflammatory agents, Analgesics

Schedule

Schedule H

Pubchem.ncbi.nlm.nih.gov. 2021. Acetaminophen. [online] Available at: < [Accessed 22 April 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/1983>

Pubchem.ncbi.nlm.nih.gov. 2021. Diclofenac. [online] Available at: < [Accessed 17 May 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Diclofenac>

Drugs, H., 2021. Acetaminophen: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 27 July 2021].

https://medlineplus.gov/druginfo/meds/a681004.html>

Medicines.org.uk. 2021. Diclofenac Sodium 50mg Gastro-Resistant Tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 27 July 2021].

https://www.medicines.org.uk/emc/product/2660>

Fdaghana.gov.gh. 2021. [online] Available at: < [Accessed 28 July 2021].

https://fdaghana.gov.gh/img/pils/Pedol%20Tablets%20(Paracetamol%20and%20Diclofenac%20Sodium).pdf>
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Information on this page was last updated on 20 Oct 2021

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