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Dica (100/50 mg) Tablet

Manufactured byLark Laboratories Ltd.
ContainsAceclofenac (100 mg) + Diacerein (50 mg)
Description

Dica (100/50 mg) Tablet is a combination medicine used in the treatment of osteoarthritis of the knee or hip joints. It is not recommended for use in children and adolescents.

Side effects

Major & minor side effects for Dica (100/50 mg) Tablet

  • Stomach discomfort and pain
  • Yellowing of skin and eyes
  • Intense yellow urine
  • Increase in liver enzyme levels
  • Abdominal pain
  • Constipation
  • Diarrhea
  • Nausea and vomiting
  • Skin rash

Uses of Dica (100/50 mg) Tablet

What is it prescribed for?

  • Osteoarthritis
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of serious side effects such as severe gastrointestinal bleeding, dizziness, fatigue, weakness, rashes, nausea, joint pain, fever, etc.
  • Is this a habit forming medicine?
    No habit-forming tendency has been reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women. Your doctor may prescribe a safer alternative based on the clinical condition.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women. Your doctor may prescribe a safer alternative based on the clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to aceclofenac, any other NSAIDs, diacerein, or any other anthraquinones.

Severe kidney damage

This medicine is not recommended for use in patients having a severe impairment of kidney function due to the increased risk of serious adverse effects.

Asthma

This medicine is not recommended for use in patients with a history of asthma due to the increased risk of worsening of the patient's condition.

Bleeding disorder

This medicine is not recommended for use in patients with bleeding disorders due to the increased risk of excessive bleeding.

Severe liver impairment

This medicine is not recommended for use in patients with a known history of severe liver impairment due to the increased risk of serious adverse effects.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women. Your doctor may prescribe a safer alternative based on the clinical condition.

Breast-feeding

This medicine is not recommended for use in breastfeeding women. Your doctor may prescribe a safer alternative based on the clinical condition.
General warnings

Diarrhea

Use of this medicine may cause diarrhea or loose stools in the first few days of treatment. Contact your doctor if the complication is not resolved within 3-4 days.

Antibiotic therapy

This medicine should not be taken with antibiotics since the risk of gastric irritation and persistent diarrhea is significantly high in such cases. Your doctor may make appropriate changes to your therapy based on your clinical condition.

Kidney disease

This medicine should be used with caution in patients with a known history of impairment of kidney function. Appropriate dose adjustments and regular monitoring of kidney functions are recommended while using this medicine.

Diagnostic tests

It is recommended to monitor liver function, kidney function, complete blood count, and urine tests every six months while taking this medicine.

Intense yellowing of urine

Use of this medicine may cause intense yellow coloration of the urine. This is mainly due to the excretion of end products and may not be indicative of any complication.

Gastro-intestinal bleeding

This medicine should be used with extreme caution due to the increased risk of severe gastrointestinal bleeding, especially with prolonged use. This risk is significantly higher in the elderly population and in patients with a history of gastrointestinal diseases. Report any unusual symptoms such as blood in the stool or vomit to the doctor immediately. Replacement with a suitable alternative may be required based on the clinical condition.

Heart surgery

This medicine is not recommended for use before or after a CABG (coronary artery bypass graft) procedure since it may worsen the patient's condition.

Asthma

This medicine is not recommended for use in patients with a known history of asthma or family history of asthma due to the increased risk of worsening of the patient's condition.

Impaired liver function

This medicine should be used with caution in patients suffering from liver diseases due to the increased risk of serious adverse effects. Close monitoring of liver function, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of serious side effects such as severe gastrointestinal bleeding, dizziness, fatigue, weakness, rashes, nausea, joint pain, fever, etc.
Interaction with Medicine

Lithium

Aluminium Hydroxide/Magnesium Hydroxide

Digoxin

Corticosteroids

Antihypertensives

Amoxycillin

Laxatives

Disease interactions

Irritable bowel syndrome

This medicine should be used with caution in patients having an irritable bowel or other associated conditions of the gastrointestinal tract due to an increase in the risk of adverse effects.

Kidney Disease

This medicine is not recommended for use in patients having a severe impairment of the normal kidney function. Appropriate diagnostic tests must be performed to rule out any kidney disease before treatment with this medicine is initiated. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Asthma

This medicine is not recommended for use in patients with a known history of NSAID-sensitive asthma. Replacement with a suitable alternative should be done under your doctor's supervision.

Gastro-Intestinal toxicity

This medicine may cause damage to the stomach, intestines, liver, etc., especially on prolonged use. Report any symptoms such as chronic indigestion, blood in stool or vomit, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Food interactions
A diet rich in dietary fibers and phytates may interfere with the absorption of this medicine. Hence, administration of this medicine with a diet rich in fibers and phytates should be avoided. Your doctor/dietitian may suggest appropriate changes in your diet based on your clinical condition.
Lab interactions
Information not available.
Take this medicine exactly as prescribed by the doctor. Do not take in larger or smaller quantities than recommended. Consult the doctor if you experience any undesirable side effects. Contact your doctor if you experience prolonged diarrhea in the initial phase of treatment. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

To be taken immediately after food

To be taken as instructed by doctor

May cause sleepiness

How it works
Aceclofenac works by reducing the formation of certain substances in the body that cause pain and swelling. Diacerein works by blocking the actions of a certain specific protein that causes swelling, pain, and degradation of cartilage at bone joints. The combination is thus effective in the treatment of osteoarthritis.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Nonsteroidal anti-inflammatory agents, Antirheumatics

Schedule

Schedule H

DailyMed - Clanza CR- aceclofenac tablet, film coated [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 2 March 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=8a023942-01e8-4849-aa3c-1a640ffc7fd3

[Internet]. 2017 [cited 2 March 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/32903#Productinfo

Diacerein - DrugBank [Internet]. Drugbank.ca. 2017 [cited 13 July 2017]. Available from:

https://www.drugbank.ca/drugs/DB11994

[Internet]. 2017 [cited 13 July 2017]. Available from:

http://highnoon-labs.com/wp-content/uploads/2015/04/Artrodar-Insert.pdf

Fidelix T, Macedo C, Maxwell L, Fernandes Moça Trevisani V. Diacerein for osteoarthritis [Internet]. 2017 [cited 13 July 2017]. Available from: http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD005117.pub3/full

http://onlinelibrary.wiley.com/cochranelibrary/search/.

Bhat T, Bhat J, Bhat F. Comparative Analysis of Analgesic Efficacy, Safety and Compliance of fixed dose combination (Aceclofenac+ Diacerein) versus free drug combination in 4oo patients of early Osteoarthritis knee [Internet]. Ssjournals.com. 2017 [cited 19 September 2017]. Available from:

http://www.ssjournals.com/index.php/ijpr/article/view/4168
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Information on this page was last updated on 2 Oct 2017

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