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Diabose M (500/50 mg) Tablet
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Diabose M (500/50 mg) Tablet

Manufactured byMicro Labs Ltd.
ContainsMetformin (500 mg) + Acarbose (50 mg)
Description
Diabose M (500/50 mg) Tablet is a combination Metformin and Acarbose. It is an anti-diabetic medicine used in the treatment of Type 2 Diabetes Mellitus (a condition in which your blood sugar levels are high because your body does not use the insulin hormone it makes properly to move sugar from the blood into the cells). This medicine works by decreasing the absorption of sugar from the intestine. It also improves the body’s response to insulin (a hormone that enables your body to use sugar) and decreases sugar production in the liver. Diabose M (500/50 mg) Tablet shows common side effects such as diarrhoea, stomach upset, low sugar level, nausea, headache, etc. These side effects usually subside with time. However, if they persist or worsen, consult your doctor for further assistance. Avoid driving vehicles or operating heavy machines while taking this medication, as it can cause dizziness. Avoid taking this medicine if you are allergic to it. Diabose M (500/50 mg) Tablet may be taken with or without food. Take the medicine in the dose and duration prescribed by your doctor. For ease of remembering, take this tablet around the same time every day. Do not stop taking this medicine unless advised by your doctor, even if your sugar levels are normal. Abrupt discontinuation of this medicine may worsen your condition and/or lead to further complications. Diabose M (500/50 mg) Tablet is not recommended for use if you have metabolic acidosis (increased acid levels in your blood), severe kidney problems, liver cirrhosis (scarring of the liver), or stomach and intestinal conditions such as inflammatory bowel disease (pain and swelling in the intestine), colonic ulceration (sores in the lining of the large intestine), partial intestinal obstruction (partial blockage of the small intestine in which the contents of the intestine cannot pass through it), or marked inability to digest or absorb food. Also, inform your doctor if you have other medical conditions and about your ongoing medications. Diabose M (500/50 mg) Tablet should be used with caution if you have liver, heart, or kidney problems. Consult your doctor if you are pregnant or breastfeeding before taking this medicine. Diabose M (500/50 mg) Tablet is not recommended for use in children below 18 years of age due to the lack of safety and efficacy data.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Diabose M (500/50 mg) Tablet

  • Yellow colored eyes or skin
  • Abdominal pain
  • Flatulence
  • Nausea and vomiting
  • Diarrhoea
  • Hypoglycaemia
  • Lactic Acidosis
  • Weakness
  • Chest discomfort
  • Headache
  • Runny Nose
  • Heartburn
  • Swollen joints

Uses of Diabose M (500/50 mg) Tablet

What is it prescribed for?

  • Type II Diabetes Mellitus
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The time at which Diabose M (500/50 mg) Tablet starts showing its effect is not clinically established.
  • How long do the effects of this medicine last?
    The time duration for Diabose M (500/50 mg) Tablet remains effective is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with Diabose M (500/50 mg) Tablet as it may cause alteration in your blood sugar levels.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Diabose M (500/50 mg) Tablet.
  • Can this medicine be taken during pregnancy?
    Diabose M (500/50 mg) Tablet should only be taken during pregnancy after discussing all the risks and benefits related to the medicine with your doctor.
  • Can this medicine be taken while breast-feeding?
    Due to the lack of safety information, consult your doctor before taking Diabose M (500/50 mg) Tablet if you are breastfeeding.

Allergy

Avoid taking Diabose M (500/50 mg) Tablet if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.

Gastrointestinal disease

Diabose M (500/50 mg) Tablet is not recommended if you have stomach and intestinal conditions such as inflammatory bowel disease (pain and swelling in the intestine), colonic ulceration (sores in the lining of the large intestine), partial intestinal obstruction (partial blockage of the small intestine in which the contents of the intestine cannot pass through it), or marked inability to digest or absorb food.

Severe kidney impairment

Diabose M (500/50 mg) Tablet is not recommended if you have severe kidney problems as it may worsen your condition.

Metabolic Acidosis and diabetic ketoacidosis

Diabose M (500/50 mg) Tablet is not recommended if you have metabolic acidosis (increased acid level in the body) or diabetic ketoacidosis (excessive acids such as ketones in the blood that may occur due to diabetes).

Liver cirrhosis

Diabose M (500/50 mg) Tablet is not recommended if you have liver cirrhosis, a condition in which the healthy cells of the liver are replaced by scarred tissues.
Warnings for special population

Pregnancy

Diabose M (500/50 mg) Tablet should only be taken during pregnancy after discussing all the risks and benefits related to the medicine with your doctor.

Breast-feeding

Due to the lack of safety information, consult your doctor before taking Diabose M (500/50 mg) Tablet if you are breastfeeding.
General warnings

Type I diabetes

Diabose M (500/50 mg) Tablet is not recommended for the treatment of Type I diabetes (no production of sugar-regulating hormone i.e. insulin in the body).

Liver or kidney condition

Diabose M (500/50 mg) Tablet should be used with caution if you have liver or kidney problems as it may worsen your condition. Follow all the instructions given by your doctor.

Congestive heart failure

Diabose M (500/50 mg) Tablet should be used with caution if you have congestive heart failure (inability of the heart to pump a sufficient amount of blood) as it can worsen your condition.

Use in children

Diabose M (500/50 mg) Tablet is not recommended in children below 18 years of age.

Use in elderly

Diabose M (500/50 mg) Tablet should be used with caution in the elderly due to the increased risk of undesired effects.

Missed Dose

Do not miss the dose of Diabose M (500/50 mg) Tablet. In case you miss a dose, take it as soon as you remember. However, if it is time for the next dose, then skip the missed dose. Do not double the dose to make up for the missed one.

Overdose

Do not take more than the prescribed dose of Diabose M (500/50 mg) Tablet. Seek emergency medical treatment in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with Diabose M (500/50 mg) Tablet as it may cause alteration in your blood sugar levels.
Interaction with Medicine

Aripiprazole

Estradiol

Gatifloxacin

Iodinated Contrast Media

Disease interactions

Vitamin B12 deficiency

Diabose M (500/50 mg) Tablet interferes with the absorption of Vitamin B12 in your body. Hence, this medicine should be used with caution if you have vitamin B12 deficiency. Inform your doctor if you are taking vitamin B12 supplements before starting the treatment.

Hypoglycaemia

Diabose M (500/50 mg) Tablet should be used with caution as it may cause hypoglycaemia (abnormally low blood sugar level). Monitor your blood sugar levels regularly. Always carry a fast-acting sugar source (like sugar candy or fruit juice) to counteract the effects of hypoglycaemia.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Diabose M (500/50 mg) Tablet as prescribed by your doctor. Do not break, crush, or chew the tablet. Swallow it as a whole with an adequate amount of water. Do not take in larger or smaller amounts than prescribed. Your doctor may change the dose over time based on the therapeutic response and clinical condition. Do not discontinue the medicine without consulting your doctor, even if your sugar level is normal. Regular monitoring of blood sugar levels is recommended during treatment with this medicine. Consult your doctor if you experience any undesirable effects that persist or worsen. Always carry a sugar candy with you to counteract the unexpected lowering of blood sugar levels.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Diabose M (500/50 mg) Tablet is a combination Metformin and Acarbose. Metformin works by improving the body’s response to insulin (a hormone that enables your body to use sugar) and decreasing sugar production in the liver. Acarbose works by decreasing the absorption of sugar into the blood from the small intestine by inhibiting the action of a chemical substance that converts carbohydrates to sugar.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Oral anti-diabetic combinations, Combination of oral biguanidies and alpha-glucosidase inhibitors

Schedule

Schedule H

Accessdata.fda.gov. 2022. [online] Available at: [Accessed 28 July 2022].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/020357s037s039,021202s021s023lbl.pdf

2022. [online] Available at: [Accessed 28 July 2022].

https://www.bayer.com/sites/default/files/2020-11/glucobay-pm-en.pdf

Accessdata.fda.gov. 2022. [online] Available at: [Accessed 28 July 2022].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/020482s024lbl.pdf
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Information on this page was last updated on 14 Sep 2022

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