Dextran

Description

Dextran is a plasma expander used in the treatment of shock, venous thromboembolism, etc. Close monitoring of kidney and liver functions is necessary while receiving this medicine.

Side effects

Major & minor side effects for Dextran

  • Chest tightness
  • Decreased blood pressure
  • Wheezing
  • Injection site pain

Uses of Dextran

What is it prescribed for?

  • Shock
  • Venous thromboembolism
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is subject to vary based on the individual and strength of administration.
  • Duration of effect
    The amount of time for which this medicine remains effective is subject to vary based on the individual and strength of administration.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to dextran or any other inactive ingredients present in the formulation.

Blood disorders

This medicine is not recommended for use in patients with blood disorders like thrombocytopenia, hypofibrinogenemia, etc. due to the increased risk of worsening of the patient's condition.

Severe bleeding disorders

This medicine is not recommended for use in patients with severe bleeding disorders due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
General warnings

Other medicines

Dextran may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Kidney Disease

This medicine should be used with caution in patients with kidney diseases due to the increased risk of adverse effects. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Missed Dose

Since this medicine is mostly given before and during a surgical procedure, the likelihood of missing a dose is very less.

Overdose

Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Enoxaparin

Dabigatran

Apixaban

Prasugrel

Disease interactions

Kidney Disease

This medicine should be used with extreme caution in patients with kidney diseases due to the increased risk of adverse effects. Regular monitoring of kidney function tests is necessary for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works
It works by increasing the volume of blood by decreasing the viscosity and enhances the blood flow.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Plasma expanders

Schedule

Schedule H

Dextran [Internet]. Glowm.com. 2019 [cited 4 January 2019]. Available from:

http://www.glowm.com/resources/glowm/cd/pages/resources/Pharmacy/Dextran.htm

[Internet]. Dailymed.nlm.nih.gov. 2019 [cited 4 January 2019]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=3c273512-84e2-2cea-b201-12345a6bd1fe#pubmed-menu

Dextran 40 - DrugBank [Internet]. Drugbank.ca. 2019 [cited 4 January 2019]. Available from:

https://www.drugbank.ca/salts/DBSALT002684

Dextran [Internet]. Pubchem.ncbi.nlm.nih.gov. 2019 [cited 4 January 2019]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/dextran#section=Pharmacology-and-Biochemistry

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Information on this page was last updated on 10 Sep 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.