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Deriva-BPO gel
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Deriva-BPO gel

Manufactured byGlenmark Pharmaceuticals Ltd.
ContainsAdapalene (0.1 %w/w) + Benzoyl Peroxide (Topical) (2.5 %w/w)
Description
Deriva-BPO gel is a medicine that consists of Adapalene and Benzoyl peroxide. It is used for the treatment of acne (pimples, blackheads and whiteheads) on your face, back, and chest caused by bacteria. It helps in reducing excess oil production, blackheads, whiteheads or painful lumps beneath your skin. This medicament works by stopping the growth of bacteria and reducing sebum secretion that causes acne. Deriva-BPO gel may cause some side effects such as dryness, redness of the skin, skin rash, itching and burning sensation at the site of application. Contact your doctor if these side effects persist for a long time. Avoid applying this medicine to broken skin or cuts. Do not use this medicine if you are allergic to it. Deriva-BPO gel should be used as instructed by your doctor. Wash your hands before and after use. It is for external use only. Avoid contact with your eyes and mouth. Inform your doctor about any other anti-acne medicines that you may be using before taking this medicine. Deriva-BPO gel may not be suitable for all people. It is not safe to be used in children below 12 years of age as the safety and efficacy data are not available. Consult your doctor if you are pregnant, planning a pregnancy, or are breastfeeding before using this medicine.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Deriva-BPO gel

  • Burning sensation at the application site
  • Redness of the skin
  • Dry or scaly skin
  • Unusually warm skin
  • Swelling of skin at the application site

Uses of Deriva-BPO gel

What is it prescribed for?

  • Acne vulgaris
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The time required for Deriva-BPO gel to start showing its effect is not known.
  • How long do the effects of this medicine last?
    The duration of action of Deriva-BPO gel is not known.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Deriva-BPO gel.
  • Can this medicine be taken during pregnancy?
    Deriva-BPO gel is not recommended for use during pregnancy as animal studies have shown harmful effects on the developing baby. Hence, consult your doctor before using this medicine.
  • Can this medicine be taken while breast-feeding?
    Deriva-BPO gel considered safe to be used in breastfeeding. However, if you are breastfeeding, consult your doctor before using this medicine.

Allergy

Avoid using Deriva-BPO gel if you are allergic to it. Inform your doctor if you have a history of allergy to this medication. If you notice any symptoms such as skin rash, itching, blisters, swelling, hives, etc., inform your doctor and seek medical attention immediately.
Warnings for special population

Pregnancy

Deriva-BPO gel is not recommended for use during pregnancy as animal studies have shown harmful effects on the developing baby. Hence, consult your doctor before using this medicine.

Breast-feeding

Deriva-BPO gel considered safe to be used in breastfeeding. However, if you are breastfeeding, consult your doctor before using this medicine.
General warnings

Skin peeling and skin irritation

Do not use Deriva-BPO gel with other topical anti-acne agents unless directed by your doctor. It can increase the risk of side effects such as skin peeling, irritation, or dryness.

For external use

Deriva-BPO gel is recommended for external use only. Avoid contact with your eyes, mouth, or open wounds. Rinse thoroughly with water in case of accidental contact.

Use in children

Avoid using Deriva-BPO gel in children less than 12 years of age since the safety and efficacy data are not available.

Waxing

Do not use waxing for removing hair on the area treated with Deriva-BPO gel due to the increased risk of skin erosions (breakdown of the outer layers of the skin).

Missed Dose

Apply the missed dose of Deriva-BPO gel as soon as you remember. Do not apply more quantities to compensate for the missed dose.

Overdose

An overdose of Deriva-BPO gel is not likely to cause severe symptoms unless it is applied for a prolonged period of time in large amounts. However, swallowing this medicine may cause harm and immediate medical intervention may be required.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Tretinoin/ Isotretinoin

Dapsone

Disease interactions

Eczema

Eczema is a skin condition in which there is itchiness, swelling, and cracked skin. Do not use Deriva-BPO gel if you have eczema as it may cause severe skin irritation on the eczematous skin.

Sunburn

Use Deriva-BPO gel with caution if you have sunburnt skin. This medicine may cause an increased risk of extreme irritation of the skin. Avoid prolonged exposure to sunlight or sunlamps and use sunscreen or protective clothing during treatment with this medicine.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Deriva-BPO gel is used to treat acne. Apply a thin layer of gel to the affected area as instructed by your doctor. Follow all the usage instructions mentioned on the label or the package insert. Finish your entire course of treatment even if your symptoms begin to clear up after a few days. You may have to use this medicine for months or even longer in some cases to keep your acne under control. Inform your doctor if you are on any other anti-acne medications before beginning the treatment with this medicine. Store Deriva-BPO gel at room temperature away from sunlight. Discard the medicine if it has reached the date of expiry. Keep the medicine away from children and pets.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works
Deriva-BPO gel is a combination of Adapalene and Benzoyl peroxide. Adapalene controls the production of excess sebum (skin’s natural oil), removes any dead skin cells and unclogs the pores. Benzoyl peroxide kills or stops the growth of bacteria that cause acne.
Legal Status

Approved

Approved

Unknown

Approved

Classification

Category

Topical acne agents

Schedule

Schedule H

Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 28 April 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/022320s004lbl.pdf>

Medicines.org.uk. 2021. Epiduo 0.1%/2.5% Gel - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 28 April 2021].

https://www.medicines.org.uk/emc/product/451/smpc>

Pubchem.ncbi.nlm.nih.gov. 2021. Adapalene. [online] Available at: < [Accessed 28 April 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Adapalene>

Pubchem.ncbi.nlm.nih.gov. 2021. Benzoyl peroxide. [online] Available at: < [Accessed 28 April 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Benzoyl-peroxide>
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Information on this page was last updated on 22 Dec 2021

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