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Deriphyllin-AX Tablet SR
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Deriphyllin-AX Tablet SR

Manufactured byZydus Cadila
ContainsEtofylline (231 mg) + Theophylline (69 mg) + Ambroxol (75 mg)
Description
Deriphyllin-AX Tablet SR is a combination medicine which may be used to prevent and treat wheezing, shortness of breath, chest tightness associated with lung diseases like asthma, bronchitis, emphysema, and other lung diseases, etc.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Deriphyllin-AX Tablet SR

  • Nausea and Vomiting
  • Skin rash and itching
  • Irregular heart rate
  • Convulsions (seizures)
  • Stomach discomfort and pain
  • Diarrhea
  • Headache
  • Sleeplessness
  • Swelling of ankles or feet
  • Yellowing of skin and eyes
  • Increased urination frequency
  • Twitching and unusual movement of muscles
  • Elevated liver enzymes

Uses of Deriphyllin-AX Tablet SR

What is it prescribed for?

  • Emphysema with bronchitis pneumoconiosis
  • Tracheobronchitis
  • Acute exacerbations of bronchitis
  • Asthma
  • Other lung diseases causing bronchospasms
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Gastric ulceration

This medicine is not recommended for use in patients with a known history of gastric ulcers due to the increased risk of worsening of the patient’s condition.

Stevens-Johnson syndrome

This medicine is not recommended for use in patients with a known history of Stevens-Johnson syndrome, which is a rare but serious disorder of the skin, due to the increased risk of worsening of the patient's condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to etofylline, theophylline, ambroxol or any other inactive ingredients present in the formulation.

Porphyria

This medicine is not recommended for use in patients with a known history of porphyria (a rare genetic disorder of the blood) due to the increased risk of worsening of the patient’s condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Other diseases

Report the instance of any disease of the heart and blood vessels, brain, thyroid glands etc to the doctor before receiving this medicine. This medicine should be used with caution and any disease worsening symptom should be reported to the doctor immediately. An alternative treatment option should be considered in some cases based on the clinical condition.

Other medicines

This medicine may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Smoking

This medicine tends to be less effective if you smoke or consume tobacco products. Avoid or limit the uptake of tobacco products while taking this medicine.

Fever

This medicine should be used with caution if you have a high fever (febrile) with a headache, chills, and joint pain. Report any such instance to the doctor while taking this medicine.

Use in the elderly

This medicine should be used with caution in the elderly as the risk of adverse effects are significantly higher.

Driving or operating machinery

This medicine may cause blurred vision or drowsiness in some patients. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Carbamazepine

Fluvoxamine

Lithium

Phenytoin

Propranolol

Ethinyl Estradiol

Cimetidine

Ciprofloxacin

Azithromycin

Riociguat

Disease interactions

Peptic ulcer

This medicine should be administered with caution in patients with active peptic ulcer disease as the risk of worsening of symptoms is very high. Report any unusual symptoms to the doctor on priority. Appropriate dose adjustment or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Kidney Disease

This medicine should be used with caution in patients with a known history of kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Seizure disorders

This medicine should be used with caution in patients with a known history of seizure disorder due to the increased risk of worsening of the patient's condition. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Heart rhythm disorders

This medicine should be used with caution in a patient suffering from a heart rhythm disorder due to the increased risk of worsening of the patient's condition. Suitable clinical investigations should be performed to determine the safe and effective use of this medicine. An alternative treatment option should be considered in some cases based on the clinical condition.
Food interactions
Avoid or limit the uptake of caffeine while taking this medicine. Report any incidence of an adverse effect to the doctor on priority.
Avoid consumption of tobacco and marijuana while taking this medicine. The risk of adverse effects is high even with secondhand smoking.
Lab interactions

Serum Uric acid test

Report the use of this medicine before undergoing a test to determine the level of uric acid in the serum. This medicine may interfere with the results and may give a false positive result for the procedure.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take this medicine as instructed by the doctor. You should adhere to any dose changes instituted by the doctor over the course of treatment. Do not take this medicine in larger or smaller quantities than prescribed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Ambroxol works by promoting mucus clearance and easing a productive cough. Etofylline and Theophylline relax the blood vessels and smooth muscles of the airways to reduce the symptoms of asthma, bronchitis, etc.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Methylxanthines, Antiasthmatic combinations, Mucolytics

Schedule

Schedule H

Ambroxol - DrugBank [Internet]. Drugbank.ca. 2017 [cited 11 July 2017]. Available from:

https://www.drugbank.ca/drugs/DB06742

Theophylline - DrugBank [Internet]. Drugbank.ca. 2017 [cited 18 May 2017]. Available from:

https://www.drugbank.ca/drugs/DB00277

Etofylline [Internet]. Pubchem.ncbi.nlm.nih.gov. 2019 [cited 27 September 2019]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/etofylline

Theophylline: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2019 [cited 27 September 2019]. Available from:

https://medlineplus.gov/druginfo/meds/a681006.html
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Information on this page was last updated on 15 Nov 2019

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