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Dependal M Suspension
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Dependal M Suspension

Manufactured byGLAXOSMITHKLINE PHARMACEUTICALS LTD
ContainsFurazolidone (25 mg/5 ml) + Metronidazole (75 mg/5 ml)
Description
Dependal M Suspension is a combination medicine which may be used for the treatment of bacterial and protozoal infections such as giardiasis, amebiasis, trichomoniasis, enteritis, etc. It may also be used for the treatment of infectious diarrhea caused by bacteria or protozoa.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Dependal M Suspension

  • Nausea and Vomiting
  • Stomach pain
  • Headache
  • Skin rash, red or itchy skin
  • Unusual tiredness or weakness
  • Agitation
  • Blurred vision
  • Convulsions
  • Fever and chills
  • Vaginal irritation
  • Loss of appetite
  • Constipation
  • Yellow colored eyes or skin
  • Abdominal pain
  • Dizziness
  • Change in taste/ Metallic taste
  • Dry mouth

Uses of Dependal M Suspension

What is it prescribed for?

  • Protozoal Infections
  • Bacterial infections
  • Bacterial and Protozoal diarrhea
  • Bacterial Vaginosis
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of this medicine can be observed in 1 to 2 hours of administration of the dose.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with this medicine due to the risk of side effects such as dizziness, drowsiness, and difficulty concentrating. Avoid performing activities that need high mental alertness like driving a vehicle or operating heavy machinery if alcohol and this medicine are used together.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to Furazolidone, Metronidazole, other nitroimidazoles, or any other inactive ingredients present in the formulation.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Kidney Disease

This medicine should be used with caution in patients with kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Liver Disease

This medicine should be used with caution in patients suffering from liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Other uses

Your doctor may prescribe this medicine for indications other than those stated above in certain specific circumstances, especially if other medicines are not effective. All the risks and benefits should be discussed with the doctor in such cases.

Blood cell count

Use of this medicine may lower the blood cell count and may lead to leukopenia, thrombocytopenia, and bone marrow aplasia. Close monitoring of WBC count, platelets is necessary. Discontinue the treatment if any signs of low blood cell count appear.

Neurologic Toxicity

Use of this medicine may cause neurological effects like convulsions and peripheral neuropathy. Inform the doctor if you have any neurological problems. Any symptoms of convulsions, tingling or burning sensation of hands and feet should be reported to the doctor.

Driving or Operating machinery

Use of this medicine may cause blurred vision or dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Missed Dose

Take/Administer the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the risk of side effects such as dizziness, drowsiness, and difficulty concentrating. Avoid performing activities that need high mental alertness like driving a vehicle or operating heavy machinery if alcohol and this medicine are used together.
Interaction with Medicine

Amitriptyline

Warfarin

Ethinyl Estradiol

Captopril

Atorvastatin

Disulfiram

Clemastine

Diltiazem

Chlorpromazine

Lithium

Disease interactions

G6PD deficiency

This medicine should be used with extreme caution in patients with G6PD deficiency due to the risk of worsening of the patient's condition. Close monitoring of the clinical condition, appropriate dose adjustments or replacement with a suitable alternative might be required in some cases.

Colitis

This medicine should be used with caution in patients with gastrointestinal diseases, especially colitis due to the increased risk of worsening of the patient's condition. Close monitoring of the clinical condition, appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Liver Disease

This medicine should be used with caution in patients with liver diseases due to the increased risk of worsening of the patient's condition. Regular monitoring of liver function tests is necessary for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Consumption of food or beverages containing high tyramine content is not recommended during treatment with this medicine. Report any unusual symptoms such as severe headache, confusion, blurred vision, problems with speech or balance, nausea, vomiting, chest pain, convulsions, numbness or weakness, etc. to the doctor immediately.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take/Administer this medicine exactly as advised by the doctor. Do not take in larger amounts than advised/prescribed. Consult the doctor if you experience any undesirable effects. Do not stop taking the medicine before completion of the course/without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by inhibiting the growth of bacteria and protozoa by interfering with DNA synthesis.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Miscellaneous antibiotics, Anti-infectives, Anthelmintics

Schedule

Schedule H

[Internet]. 2019 [cited 21 May 2019]. Available from:

https://www.medicines.org.uk/emc/medicine/26716

DailyMed - Metronidazole tablet [Internet]. Dailymed.nlm.nih.gov. 2019 [cited 21 May 2019] Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a66abf44-9ae9-4342-b69a-ebaa1f9b7d78

Furazolidone - DrugBank [Internet]. Drugbank.ca. 2019 [cited 21 May 2019]. Available from:

https://www.drugbank.ca/drugs/DB00614

Furazolidone [Internet]. Pubchem.ncbi.nlm.nih.gov. 2019 [cited 21 May 2019]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/furazolidone
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Information on this page was last updated on 29 May 2019

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