Darifenacin

Description

Darifenacin is used for the treatment of an overactive bladder, a condition characterized by symptoms such as a frequent feeling of a need to urinate, sudden urge to urinate, inability to control urination, leaking of urine, etc. This medicine is not recommended for use in patients less than 18 years of age.

Side effects

Major & minor side effects for Darifenacin

  • Dry mouth
  • Constipation
  • Dry eyes
  • Nausea and Vomiting
  • Abdominal pain
  • Dry skin
  • Cough
  • Nasal dryness
  • Weight gain
  • Headache
  • Dizziness
  • Back pain

Uses of Darifenacin

What is it prescribed for?

  • Overactive Bladder
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The effect of this medicine lasts for an average duration of 24 hours.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit forming tendency has been reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. If the medicine is used, close monitoring of the infant for any undesired side effects is recommended.

Allergy

This medicine is not recommended for use in patients with a known allergy to darifenacin or any other inactive ingredients present along with it.

Severe liver impairment

This medicine is not recommended for use in patients suffering from severe liver function impairment due to the increased risk of worsening of the patient's condition.

Urinary retention

This medicine is not recommended for use in patients suffering from urinary retention, a condition where the patient is unable to completely or partially empty the bladder, since it may worsen the patient's condition.

Narrow angle glaucoma

This medicine is not recommended for use in patients suffering from an uncontrolled narrow-angle glaucoma due to the increased risk of worsening of the patient's condition.

Gastric retention

This medicine is not recommended for use in patients suffering from gastric retention due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. If the medicine is used, close monitoring of the infant for any undesired side effects is recommended.
General warnings

Angioedema and anaphylactic reactions

This medicine may cause angioedema (swelling) of the face, lips, tongue, etc. as well as severe allergic reactions in some patients. Seek immediate medical intervention if any such reactions develop. Appropriate patient/caregiver counseling, corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Liver impairment

This medicine should be used with caution in patients suffering from a mild-to-moderate liver function impairment due to the increased risk of severe adverse effects. Close monitoring of liver function is recommended for such patients. This medicine is not recommended for use in patients with severe liver function impairment. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Pediatric population

This medicine is not recommended for use in patients less than 18 years of age since the safety and efficacy of use are not clinically established.

Central nervous system effects

This medicine may cause central nervous system side effects such as a headache, confusion, hallucinations, sleepiness, etc. in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any such symptoms during treatment with this medicine. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Driving or operating machines

Use of this medicine may cause symptoms such as dizziness, drowsiness, blurred vision, etc. in some patients. If you experience any such symptoms after taking this medicine, it is advised that you do not perform any activities such as driving a vehicle or operating machinery.

Missed Dose

If a dose of this medicine is missed, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose. Do not double the dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Atazanavir

Celecoxib

Clotrimazole

Itraconazole

Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine exactly as instructed by the doctor. Do not take in larger or smaller amounts than prescribed. Seek emergency medical treatment in case of any severe adverse effects. Ensure that the course of treatment is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine relaxes the muscles of the urinary bladder; this helps the bladder to retain a larger amount of urine and prevents the symptoms of an overactive bladder.
Legal Status

Approved

Approved

Unknown

Approved

Classification

Category

Urinary antispasmodics

Schedule

Schedule H

DailyMed - Darifenacin hydrobromide tablet, extended release [Internet]. Dailymed.nlm.nih.gov. 2018 [cited 27 July 2018]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=6e8470d1-c3e6-4644-b70a-aa47ddf79676

[Internet]. Accessdata.fda.gov. 2018 [cited 27 July 2018]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/021513s010lbl.pdf

[Internet]. Pdf.hres.ca. 2018 [cited 27 July 2018]. Available from:

https://pdf.hres.ca/dpd_pm/00020092.PDF

Darifenacin - DrugBank [Internet]. Drugbank.ca. 2018 [cited 27 July 2018]. Available from:

https://www.drugbank.ca/drugs/DB00496

Darifenacin: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2018 [cited 27 July 2018]. Available from:

https://medlineplus.gov/druginfo/meds/a605039.html

Emselex 15mg prolonged release tablets - Summary of Product Characteristics (SmPC) - (eMC) [Internet]. Medicines.org.uk. 2018 [cited 27 July 2018]. Available from:

https://www.medicines.org.uk/emc/product/7019/smpc

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Information on this page was last updated on 17 Aug 2018

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.