Dacotin 100 MG Injection

Manufactured byDr. Reddys Laboratories Ltd.
ContainsOxaliplatin
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Description

Dacotin 100 MG Injection is an anticancer agent which is used in the treatment of cancer of the large intestine. It should be used under the supervision of a qualified physician. Close monitoring of kidney function and blood cell count are necessary while receiving this medication.

Side effects

Major & minor side effects for Dacotin 100 MG Injection

  • Burning or tingling sensation of hands and feet
  • Cough
  • Fever and chills
  • Low WBC and Platelet count
  • Mouth ulcers
  • Loss of appetite
  • Skin rash
  • Nausea and Vomiting
  • Swelling of eyelids, face, lips
  • Acid or sour stomach
  • Sneezing
  • Stomach discomfort and pain
  • Running Nose
  • Change in taste
  • Hair loss

Uses of Dacotin 100 MG Injection

What is it prescribed for?

  • Colorectal Cancer
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Concerns

Commonly asked questions

  • Onset of action
    The peak effect of this medicine can be observed in 2 hours after intravenous injection.
  • Duration of effect
    The effect of this medicine lasts for an average duration of 30 to 45 days.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for pregnant women.
  • Usage while breast-feeding?
    This medicine is not recommended in breastfeeding women.

Allergy

Not recommended in patients with known allergy to Dacotin 100 MG Injection or other platinum-containing compounds.

Severe myelosuppression

Not recommended in patients with low white blood cell and platelet count.
Warnings for special population

Pregnancy

This medicine is not recommended for pregnant women.

Breast-feeding

This medicine is not recommended in breastfeeding women.
General warnings

Impaired kidney function

This medicine may cause severe kidney injury. The risk may increase if taken with aminoglycoside antibiotics. Close monitoring of serum creatinine, urea, and sodium levels is necessary.

Hearing impairment

This medicine may cause the hearing problem which is more common in children. Audiometric testing should be performed before initiating the treatment and also before every dose. Any symptoms of the hearing problem should be reported to the doctor.

Allergy

This medicine may cause serious skin reactions. Discontinue the treatment if any symptoms of allergy appear and do not restart.

Blood cell count

This medicine may lower the white blood cells and platelets. Close monitoring of blood cell count is necessary. Do not start the treatment if the cell count is low.

Infections

The chances of occurring infections are more in patients receiving this medicine. Hold the chemotherapy and start with the broad-spectrum antibiotics if there are any signs and symptoms of fever. Close monitoring of the body temperature and the blood cell count is necessary.

Lung toxicity

This medicine may cause rare but fatal lung injury. Inform the doctor if you have any lung disease. Any symptoms of difficulty in breathing, non-productive cough should be reported to the doctor. Discontinue the treatment until the exact cause is identified.

Impaired liver function

This medicine may cause liver injury. The baseline of liver enzymes should be obtained before initiating the therapy. Any signs of elevation in the liver enzymes should be informed to the doctor. Discontinue the treatment until the levels reach to normal.

Neuropathy

This medicine may cause severe nerve damage which may develop within hours of adminstration and resolves within 14 days or may persist for more than 14 days. Any symptoms of tingling or burning sensation of hands and feet should be reported to the doctor.

Missed Dose

It is advised not to miss any dose. If you missed any dose, you should contact your doctor immediately.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Clozapine

Vancomycin

Atorvastatin

Live vaccines

Disease interactions

Arrhythmias

This medicine should be used with caution in patients with heart diseases due to the increase in the risk of irregular heart rhythm. Monitor the potassium levels, which may exacerbate the condition. Any symptoms of heart palpitation should be reported to the doctor.

Lung injury

This medicine may cause rare but fatal lung injury. Inform the doctor if you have any lung disease. Any symptoms of difficulty in breathing, non-productive cough should be reported to the doctor. Discontinue the treatment until the exact cause is identified.
Food interactions
Information not available.
Lab interactions
Information not available.
This medicine is given in multiple cycles. It is important to receive the every scheduled dose and make a note of next scheduled dose. Close monitoring of blood cells counts and kidney function.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
It works by stopping the growth of cancer cells by inhibiting the DNA synthesis.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Alkylating agents

Schedule

Schedule H

[Internet]. 2017 [cited 25 April 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/32296

DailyMed - Oxaliplatin injection, powder, lyophilized, for solution [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 25 April 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=3f680321-398d-4941-a5d5-e3cdef549ee0#section-5.1

Oxaliplatin Injection: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 25 April 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a607035.html

Prescribing medicines in pregnancy database [Internet]. Therapeutic Goods Administration (TGA). 2017 [cited 25 April 2017]. Available from:

https://www.tga.gov.au/prescribing-medicines-pregnancy-database#searchname
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