Dabigatran

Description

Dabigatran is an anticoagulant (blood thinner) that is used in the prevention and treatment of blood clots. It works by blocking a substance (thrombin) in your body that is involved in blood clot formation. Dabigatran may cause side effects such as bleeding, indigestion, stomach pain, diarrhoea, nausea, etc. Consult your doctor if these symptoms persist or worsen. Dabigatran should be taken exactly as directed by your doctor. Take it at the same time every day to maintain a constant level of this medicine in your body. Continue taking this medicine for the prescribed duration to effectively treat your condition. Dabigatran should be avoided if you are allergic to it. Inform your doctor if you have pre-existing kidney or liver problems before beginning treatment with this medicine. Inform your doctor if you are taking any other medicines to avoid any undesired side effects. This medicine is not recommended for use in children below 18 years of age. If you are pregnant, breastfeeding, or are planning a pregnancy, consult your doctor before taking this medication.

Side effects

Major & minor side effects for Dabigatran

  • Unusual bleeding
  • Decreased red blood cell count
  • Stomach pain
  • Indigestion
  • Diarrhoea
  • Nausea
  • Coughing up blood
  • Reduced Platelet Count
  • Stomach ulcer
  • Itching of skin
  • Vomiting

Uses of Dabigatran

What is it prescribed for?

  • Prevention and treatment of blood clots
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Concerns

Commonly asked questions

  • Onset of action
    The time required by Dabigatran to show its effect is not clinically known.
  • Duration of effect
    Dabigatran remains in your body for an approximate duration of three to four days after intake.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies have been reported with Dabigatran.
  • Usage in pregnancy?
    Dabigatran may harm your developing foetus and is not recommended during pregnancy unless necessary. Hence, consult your doctor if you are pregnant.
  • Usage while breast-feeding?
    It is not known whether Dabigatran passes into breastmilk. Hence this medicine is not recommended for use during breastfeeding unless necessary. Consult your doctor if you are breastfeeding.

Allergy

Avoid taking Dabigatran if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.

Severe kidney impairment

Dabigatran is eliminated by the kidneys. Hence it is not recommended for use if you have severe kidney impairment (loss of kidney function) due to the increased risk of side effects resulting from the accumulation of this medicine in your body.

Active bleeding

Dabigatran is not recommended for use if you have active bleeding problems or any other conditions that may increase your risk of bleeding such as stomach ulcers (painful sores on the inner lining of your stomach), injury/bleeding in your brain, recent surgery of your brain/eyes, etc. This medicine may further increase the risk of bleeding and worsen your condition.

Severe liver disease

Dabigatran is not recommended for use if you have severe liver problems due to the increased risk of a further worsening of your condition.
Warnings for special population

Pregnancy

Dabigatran may harm your developing foetus and is not recommended during pregnancy unless necessary. Hence, consult your doctor if you are pregnant.

Breast-feeding

It is not known whether Dabigatran passes into breastmilk. Hence this medicine is not recommended for use during breastfeeding unless necessary. Consult your doctor if you are breastfeeding.
General warnings

Surgery

Dabigatran may increase your risk of bleeding and should be discontinued at least 24 hours before surgical procedure. If you are at a higher risk of bleeding or in case of major surgery, your doctor may consider the discontinuation of Dabigatran two to four days before surgery. Hence, inform your doctor about the use of this medicine before undergoing any surgery.

Other Medicines

Dabigatran may interact with other medicines and cause undesired effects. Inform your doctor about your current medicines including any herbs or supplements before taking Dabigatran.

Antiphospholipid syndrome

Dabigatran is not recommended for use if you have a history of blood clots formation associated with antiphospholipid syndrome (a condition in which your immune system malfunctions and increases your risk of blood clots). Hence inform your doctor if you have such a condition before beginning treatment with this medicine.

Use in children

Dabigatran is not recommended for use in children below 18 years of age due to a lack of safety and efficacy data.

Women of childbearing potential

Women of childbearing potential should avoid pregnancy during treatment with Dabigatran due to the increased risk of side effects in the foetus.

Missed Dose

Try not to skip a dose of Dabigatran. Take the missed dose as soon as you remember. If it is time for your next dose, skip the missed one. Do not double the dose to compensate for a missed one.

Overdose

Do not take more than the prescribed dose. Contact your doctor if you suspect an overdose with Dabigatran.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Verapamil

Phenytoin

Carbamazepine

Tacrolimus

Amiodarone

Quinidine

Warfarin

Ritonavir

Ticagrelor

Ibuprofen

Ketoconazole

Heparin

Cyclosporine

Aspirin

Diclofenac

Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Dabigatran with or without food. Do not take more or less than the prescribed dose. Avoid the discontinuation of this medicine without consulting your doctor as it may worsen your condition. Dabigatran may increase your risk of bleeding. Inform your doctor if you experience any signs and symptoms of bleeding such as dizziness, lightheadedness, red/black tarry stools, coughing up or vomiting blood, severe headache, and weakness. Dabigatran may decrease your haemoglobin levels, and platelet and red blood cell count. Your doctor may suggest tests to regularly monitor your haemoglobin level and blood cell count during treatment with this medicine.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Does not cause sleepiness

How it works
Dabigatran belongs to a group of medicine called anticoagulants (blood thinners). It works by blocking a substance (thrombin) in your body that is involved in the formation of blood clots.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Thrombin inhibitors, Anticoagulants

Schedule

Schedule H

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https://medlineplus.gov/druginfo/meds/a610024.html>

Ebs.tga.gov.au. 2021. TGA eBS - Product and Consumer Medicine Information Licence. [online] Available at: < [Accessed 10 November 2021].

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Information on this page was last updated on 27 Dec 2021

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We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.