Cyproterone Acetate

Description

Cyproterone Acetate is used to treat some types of prostate cancers. It may also be used to reduce abnormal sex drive in men. It may also be used in a combination with other medicines to treat conditions such as acne, loss of hair (alopecia), excessive facial hair growth in women (hirsutism), etc.

Side effects

Major & minor side effects for Cyproterone Acetate

  • Tiredness
  • Headache
  • Nausea
  • Shortness of breath
  • Depressed mood
  • Changes in weight
  • Sweating and flushing
  • Breast pain
  • Swelling of ankles or feet
  • Dry skin

Uses of Cyproterone Acetate

What is it prescribed for?

  • Prostatic carcinoma
  • Reduction of Drive in Sexual Deviations
  • Androgenization
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Consumption of alcohol is not recommended during treatment with Cyproterone Acetate since alcohol may reduce the effectiveness of this medicine.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women due to the increased risk of harmful effects on the unborn baby.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women.

Allergy

This medicine is not recommended for use in patients with a known allergy to cyproterone or any other inactive ingredients present along with it.

Rotor Syndrome

This medicine is not recommended for use in patients suffering from Rotor syndrome due to the increased risk of worsening of the patient's condition.

Dublin-Johnson Syndrome

This medicine is not recommended for use in patients suffering from Dublin-Johnson syndrome due to the increased risk of worsening of the patient's condition.

Severe Chronic Depression

This medicine is not recommended for use in patients suffering from severe chronic depression since it may worsen the patient's condition.

Sickle cell anemia

This medicine is not recommended for use in patients suffering from sickle cell anemia since it may worsen the patient's condition.

Liver Disease

This medicine is not recommended for use in patients with a history of liver diseases or patients with a history of liver tumors not caused due to metastases from the prostate cancer since it may worsen the patient's condition.

Benign Brain Tumour (Meningioma)

This medicine is not recommended for use in patients suffering from a benign brain tumor (meningioma) due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women due to the increased risk of harmful effects on the unborn baby.

Breast-feeding

This medicine is not recommended for use in breastfeeding women.
General warnings

Diabetes Mellitus

This medicine should be used with extreme caution in patients suffering from diabetes mellitus since it may reduce the effectiveness of anti-diabetic medications. Close monitoring of blood sugar levels is recommended for these patients. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Osteoporosis

This medicine should be used with caution in patients with a known history of osteoporosis due to the increased risk of worsening of the patient's condition. Close monitoring of clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Hepatic Impairment

This medicine is not recommended for use in patients suffering from liver diseases due to the increased risk of worsening of the patient's condition. Replacement with a suitable alternative should be considered under the supervision of your doctor.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with Cyproterone Acetate since alcohol may reduce the effectiveness of this medicine.
Interaction with Medicine

Antidiabetic medicines

Phenytoin

Ketoconazole

Rifampicin

Ritonavir

Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine as advised by your doctor. You are recommended to take it after a meal. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the course of treatment is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

To be taken after food

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine inhibits the actions of certain hormones in the body (androgens) to bring about its therapeutic effects.
Legal Status

Approved

Unknown

Unknown

Approved

Classification

Category

Antiandrogens

Schedule

Schedule H

Cyproterone acetate - DrugBank [Internet]. Drugbank.ca. 2018 [cited 1 August 2018]. Available from:

https://www.drugbank.ca/drugs/DB04839

[Internet]. Cipla.co.za. 2018 [cited 1 August 2018]. Available from:

https://www.cipla.co.za/wp-content/uploads/2013/10/sep_cipla-cyproterone-50mg.pdf

[Internet]. Medicines.org.uk. 2018 [cited 1 August 2018]. Available from:

https://www.medicines.org.uk/emc/files/pil.3127.pdf

[Internet]. Medicinewise-cmi.s3.amazonaws.com. 2018 [cited 1 August 2018]. Available from:

https://medicinewise-cmi.s3.amazonaws.com/cmi201805/pdf/cmi/CMR11138.pdf

[Internet]. Medsafe.govt.nz. 2018 [cited 1 August 2018]. Available from:

http://www.medsafe.govt.nz/profs/Datasheet/s/Siteronetab.pdf

TGA eBS - Product and Consumer Medicine Information Licence [Internet]. Ebs.tga.gov.au. 2018 [cited 1 August 2018]. Available from:

https://www.ebs.tga.gov.au/ebs/picmi/picmirepository.nsf/pdf?OpenAgent&id=CP-2015-CMI-02665-1&d=201808011016933

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Information on this page was last updated on 20 Aug 2018

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.