Cyproheptadine

Description

Cyproheptadine is a first-generation antihistamine used for the treatment of conditions such as allergic reactions, allergic rhinitis, migraine, cluster headache, etc. This medicine is not recommended for use in patients less than 2 years of age.

Side effects

Major & minor side effects for Cyproheptadine

  • Vomiting
  • Nausea
  • Fatigue
  • Dizziness
  • Headache

Uses of Cyproheptadine

What is it prescribed for?

  • Allergic Rhinitis
  • Urticaria
  • Pruritus
  • Anorexia Nervosa
  • Migraine
  • Cluster headache
  • Cushing's syndrome
  • Allergic conjunctivitis
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Concerns

Commonly asked questions

  • Onset of action
    The effect of this medicine can be observed within 15 to 60 minutes of administration of the dose.
  • Duration of effect
    The effect of this medicine lasts for an average duration of 8 to 12 hours.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may suggest an alternative medicine based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to cyproheptadine or any other inactive ingredients present along with it.

Narrow-angle glaucoma

This medicine is not recommended for use in patients suffering from narrow-angle glaucoma due to the increased risk of worsening of the patient's condition.

Monoamine oxidase inhibitors (MAO)

This medicine is not recommended for use in patients receiving therapy with MAO inhibitors due to the increased risk of serious adverse effects.

Symptomatic Prostatic Hypertrophy

This medicine is not recommended for use in patients suffering from symptomatic prostatic hypertrophy (prostate enlargement) due to the increased risk of worsening of the patient's condition.

Elderly patients

This medicine is not recommended for use in elderly and debilitated (very weak) patients due to the increased risk of serious adverse effects.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may suggest an alternative medicine based on your clinical condition.
General warnings

Thyroid Disorder

This medicine should be used with caution in patients suffering from thyroid dysfunction due to the increased risk of severe adverse effects. Regular monitoring of thyroid function tests is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Renal impairment

This medicine should be used with caution in patients with a history of kidney diseases due to the increased risk of severe adverse effects. Regular monitoring of kidney function tests, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Driving or Operating machinery

Use of this medicine may cause symptoms such as blurred vision, dizziness, drowsiness, tiredness, etc. in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Use in Pediatrics

This medicine is not recommended for use in patients less than 2 years of age since the safety and efficacy of use are not clinically established.

Liver impairment

This medicine should be used with caution in patients with a history of liver diseases due to the increased risk of serious adverse effects. Regular monitoring of liver function tests, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Missed Dose

Take/Administer the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Propoxyphene

Sodium oxybate

Amoxapine

Aripiprazole

Topiramate

Zonisamide

Disease interactions

Asthma/ COPD

This medicine should be used with caution in patients with a history of asthma/chronic obstructive pulmonary disease due to the increased risk of worsening of the patient's condition. Report any unusual symptoms to the doctor immediately. Close monitoring of clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Cardiovascular disorders

This medicine should be used with caution in patients with a history of cardiovascular disorders due to the increased risk of worsening of the patient's condition. Report any unusual symptoms to the doctor immediately. Close monitoring of clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.
Food interactions
Information not available.
Lab interactions
Information not available.
Take/Administer this medicine with or without food. Do not consume/administer in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by blocking the action of certain substances produced by the body which are responsible for causing allergic reactions and symptoms. It also blocks the actions of certain substances in the body which are responsible for a reduction in appetite.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Antihistamines

Schedule

Schedule H

[Internet]. Risingpharma.com. 2018 [cited 31 July 2018]. Available from:

http://www.risingpharma.com/Files/Prescribing-Info/Package%20Insert-Cyproheptadine%20Syrup-2mg-5mL.pdf

[Internet]. Mhra.gov.uk. 2018 [cited 31 July 2018]. Available from:

http://www.mhra.gov.uk/home/groups/spcpil/documents/spcpil/con1500616539347.pdf

[Internet]. Accessdata.fda.gov. 2018 [cited 31 July 2018]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/087056s045lbl.pdf

[Internet]. CiplaMed. 2018 [cited 31 July 2018]. Available from:

https://ciplamed.com/content/ciplactin-tablets

Cyproheptadine - DrugBank [Internet]. Drugbank.ca. 2018 [cited 31 July 2018]. Available from:

https://www.drugbank.ca/drugs/DB00434

Cyproheptadine: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2018 [cited 31 July 2018]. Available from:

https://medlineplus.gov/druginfo/meds/a682541.html

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Information on this page was last updated on 2 Aug 2018

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.