Cyclobenzaprine

Description

Cyclobenzaprine is a skeletal muscle relaxant used to relieve muscle spasm (a condition where the muscles are contracted continuously) associated with acute, painful, musculoskeletal conditions. This medicine is used along with rest and physical therapy to get the best possible effect. It is not recommended for use in patients below 15 years of age.

Side effects

Major & minor side effects for Cyclobenzaprine

  • Yellowing of skin or eyes
  • Blurred vision
  • Skin Rash
  • Dry mouth
  • Dizziness and Drowsiness
  • Nausea and vomiting
  • Headache
  • Constipation
  • Sweating

Uses of Cyclobenzaprine

What is it prescribed for?

  • Muscle spasm
Read More
Concerns

Commonly asked questions

  • Onset of action
    The effect of this medicine can be observed within 1 hour of administration of the dose.
  • Duration of effect
    The effect of this medicine lasts for an average duration of 12 to 24 hours.
  • Safe with alcohol?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of dizziness, drowsiness, and difficulty in concentration. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to cyclobenzaprine or any other inactive ingredients present along with it.

Monoamine oxidase inhibitors (MAO)

Cyclobenzaprine is not recommended for use in patients taking monoamine oxidase inhibitors (MAOI) due to the increased risk of serious and life-threatening adverse effects. Your doctor may suggest maintaining a time gap of at least 14 days to start therapy with this medicine after discontinuing MAO inhibitors.

Hyperthyroidism

This medicine is not recommended for use in patients with hyperthyroidism (a condition where the thyroid gland produces too much of thyroid hormones) due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Driving or operating machinery

This medicine may cause dizziness or drowsiness in some patients. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Glaucoma

This medicine should be used with extreme caution in patients with a history of glaucoma, or increased intraocular pressure due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Urinary retention

This medicine should be used with extreme caution in patients with urinary retention due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Use in elderly population

This medicine should be used with extreme caution in elderly patients due to the high risk of severe adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Use in children

Safety and efficacy of the immediate-release form of this medicine have not been clinically established in children under the age of 15 years. Safety and efficacy of the extended-release form of this medicine have not been clinically established in children under the age of 15 years.

Serotonin syndrome

This medicine may cause a rare serious condition called Serotonin syndrome when used in combination with other medicines (eg, SSRIs, TCAs, or MAO inhibitors). Appropriate corrective measures, dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Liver impairment

The extended-release form of this medicine is not recommended for use in patients with liver impairment. The immediate release form of this medicine is not recommended for use in patients with moderate to severe liver impairment.

Missed Dose

Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of dizziness, drowsiness, and difficulty in concentration. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
Interaction with Medicine

Amitriptyline

Bupropion

Amoxapine

Citalopram

Duloxetine

Fluvoxamine

Disease interactions

Cardiovascular disease

This medicine is not recommended for use in patients with congestive heart failure, arrhythmias, heart block, and/or conduction disturbances due to the risk of worsening of the patient's condition. Replacement with a suitable alternative may be necessary based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine exactly as advised by your doctor. You may take this medicine with food. Do not take in larger amounts than advised/prescribed. Consult the doctor if you experience any undesirable effects. Do not stop taking the medicine before completion of the course/without consulting your doctor.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

Causes sleepiness

How it works
It acts on the nervous system and reduces muscle spasms, allowing the muscles to relax.
Legal Status

Approved

Approved

Unknown

Unknown

Classification

Category

Skeletal muscle relaxants

Schedule

Schedule H

[Internet]. Accessdata.fda.gov. 2018 [cited 21 September 2018]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2003/017821s045lbl.pdf

[Internet]. Accessdata.fda.gov. 2018 [cited 21 September 2018]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/021777s014lbl.pdf

Cyclobenzaprine: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2018 [cited 21 September 2018]. Available from:

https://medlineplus.gov/druginfo/meds/a682514.html

Cyclobenzaprine [Internet]. Pubchem.ncbi.nlm.nih.gov. 2018 [cited 21 September 2018]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/cyclobenzaprine

Cyclobenzaprine - DrugBank [Internet]. Drugbank.ca. 2018 [cited 21 September 2018]. Available from:

https://www.drugbank.ca/drugs/DB00924

How will this medicine affect me?

Consult top doctors online and get an answer now
Chat now
Chat now

Looking for a doctor?

Book an appointment with the top doctors near you
Book now
Book now
Something doesn’t feel right?
Report an error

Information on this page was last updated on 11 Feb 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.