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Cosvate-GM Cream
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Cosvate-GM Cream

Manufactured byOAKNET LIFE SCIENCES PVT LTD
ContainsClobetasol (0.05 %w/w) + Gentamicin (0.1 %w/w) + Miconazole (2 %w/w)
Description
Cosvate-GM Cream is a combination of Clobetasol, Gentamicin and Miconazole. It is used to treat skin infections caused by bacteria and fungus. It also helps to relieve redness, swelling, and itching associated with various skin conditions. It works by reducing the production of chemicals responsible for redness and swelling and stopping the growth of microorganisms responsible for infections. Cosvate-GM Cream may cause side effects like burning, irritation, itching, and redness at the application site. These symptoms last only for a very few days and disappear with time. Consult your doctor if these side effects are bothering you. Cosvate-GM Cream is applied as a thin layer to the affected areas 1-2 times a day. Wash and dry the affected areas before application. Avoid contact with your eyes and mouth. Keep the affected area clean and dry because the presence of water can increase microbial growth. If the symptoms are not resolved within seven days, consult your doctor before continuing the treatment. Cosvate-GM Cream is not recommended in children below the age of 12 years or if you are allergic to it. Inform your doctor about all your medicines as they can interact with this cream and cause side effects. Consult your doctor if you are pregnant or breastfeeding before using this medicine.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Cosvate-GM Cream

  • Skin rash
  • Redness of the skin
  • Blisters under the skin
  • Burning or tingling sensation of skin
  • Itchy and dry skin
  • Unusually warm skin
  • Lightening of skin at the area of application

Uses of Cosvate-GM Cream

What is it prescribed for?

  • Steroid responsive skin infections
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The time taken by Cosvate-GM Cream to show its effect is not clinically known.
  • How long do the effects of this medicine last?
    The duration for which Cosvate-GM Cream remains active in your body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Cosvate-GM Cream.
  • Can this medicine be taken during pregnancy?
    Cosvate-GM Cream is not recommended during pregnancy as insufficient studies are available to understand the benefits and safety of this medicine. Therefore, take this medicine only after consulting your doctor.
  • Can this medicine be taken while breast-feeding?
    Cosvate-GM Cream is not recommended for use if you are breastfeeding as it is not known if this medicine is present in breastmilk or not. Consult your doctor first before taking this medicine to understand its risks and benefits.

Allergy

Cosvate-GM Cream is not recommended for use if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, swelling and/or itching (especially of your face, lips, throat), breathing difficulty, etc.
Warnings for special population

Pregnancy

Cosvate-GM Cream is not recommended during pregnancy as insufficient studies are available to understand the benefits and safety of this medicine. Therefore, take this medicine only after consulting your doctor.

Breast-feeding

Cosvate-GM Cream is not recommended for use if you are breastfeeding as it is not known if this medicine is present in breastmilk or not. Consult your doctor first before taking this medicine to understand its risks and benefits.
General warnings

Allergic reactions

Cosvate-GM Cream may rarely cause an allergic reaction in your body. Any instance indicative of allergic reactions like redness, swelling (in any part of your body), itching etc. should be reported to your doctor promptly.

External use

Cosvate-GM Cream prescribed for external use only. Avoid contact with your eyes, nose, mouth, vagina, or any open wounds while using this cream. Rinse immediately with water if it comes in contact with these areas.

Cushing's syndrome

Prolonged use of Cosvate-GM Cream can cause Cushing's syndrome. It is a disorder in which the body makes too much of a hormone called cortisol. If you experience symptoms like swelling of your face, increased blood sugar levels, etc. then consult your doctor immediately.

Use in children

Cosvate-GM Cream is not recommended for use in children less than 12 years of age unless directed by your doctor. If used, long-term continuous treatment should be avoided.

Missed Dose

Apply the missed dose of Cosvate-GM Cream as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not apply a double dose to make up for the missed dose.

Overdose

An overdose of Cosvate-GM Cream is not likely to cause severe symptoms unless it is applied for a prolonged period] in large volumes. However, ingestion of this medicine may cause harm and immediate medical intervention may be required.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Use Cosvate-GM Cream as prescribed by your doctor. Apply a thin layer of this cream to the affected area 2-3 times a day. This medicine is for external use only. Your doctor can do a patch test (a procedure done on your skin) to see if you are allergic to this medicine or not. Do not cover the affected area by bandages. Check the expiry date before applying for this medicine. Keep it away from children and pets. Dry yourself completely after taking a shower especially between toes and fingers as fungal infections occur in warm, moist areas of the body. Avoid sharing personal items like towels and clothes with others. Wear clean clothes every day to prevent infection. Contact your doctor if your symptoms do not improve or resolve in a few weeks. Avoid using it for more than the prescribed duration.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works
Cosvate-GM Cream is composed of Cobetasol, Gentamicin and Miconazole. Clobetasol is a topical steroid that prevents the production of prostaglandins (compounds in the body made of fats that have chemical messenger like effects). Gentamicin works by preventing the formation of bacterial cell walls. This helps in stopping the growth and multiplication of the microorganism, eventually killing it. Miconazole kills the fungus by stopping their cell wall formation. It works by preventing the fungi from making a substance called ergosterol, which is necessary for the production of the cell wall.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Topical steroids with anti-infectives, Topical antifungals, Topical antibiotics

Schedule

Schedule H

Drugs, H., 2021. Clobetasol Topical: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 27 April 2021].

https://medlineplus.gov/druginfo/meds/a686008.html>

Pubchem.ncbi.nlm.nih.gov. 2021. Miconazole. [online] Available at: < [Accessed 23 April 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Miconazole>

Dailymed.nlm.nih.gov. 2021. DailyMed - GENTAMICIN SULFATE CREAM 0.1% cream. [online] Available at: < [Accessed 16 August 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a2b5d3ff-920d-280a-e053-2995a90ac84f>
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Information on this page was last updated on 22 Oct 2021

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