Concor AM (5/5 mg) Tablet

Manufactured byMerck India Ltd.
ContainsAmlodipine (5 mg) + Bisoprolol (5 mg)
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Description

Concor AM (5/5 mg) Tablet is a combination medicine used for the treatment of high blood pressure. Patients are advised to maintain a strict exercise and diet regimen along with this medicine for the best possible effect.

Substitutes

List of substitutes for Concor AM (5/5 mg) Tablet

Side effects

Major & minor side effects for Concor AM (5/5 mg) Tablet

  • Body pain
  • Runny Nose and Cough
  • Headache
  • Sneezing
  • Chest discomfort
  • Diarrhea
  • Trouble sleeping
  • Swelling of ankles or feet
  • Difficulty in breathing
  • Dizziness
  • Increased heartbeat
  • Redness of face, neck, arms and chest
  • Muscle pain
  • Stomach pain
  • Dry mouth

Uses of Concor AM (5/5 mg) Tablet

What is it prescribed for?

  • Hypertension
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Concerns

Commonly asked questions

  • Onset of action
    The effect of this medicine can be observed within 2 to 4 hours of administration of the dose.
  • Duration of effect
    The effect of this medicine lasts for an average duration of 24 hours.
  • Safe with alcohol?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, lightheadedness, irregular heart rate, and fainting. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women except in life-threatening conditions. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to bisoprolol, other beta-blockers, amlodipine, or other calcium channel blockers.

Heart diseases

This medicine is not recommended for use in patients suffering from heart diseases such as a heart block greater than first degree, cardiogenic shock, sick sinus syndrome (without a permanent pacemaker in place), sinus bradycardia, etc. since it may worsen the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women except in life-threatening conditions. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.
General warnings

Cardiac Failure

This medicine should be used with caution in patients suffering from heart diseases due to the increased risk of cardiac failure. Close monitoring of heart function is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Major surgery

This medicine should be used with extreme caution in patients undergoing a major surgery due to the increased risk of severe adverse effects. Close monitoring of heart function is recommended for such patients. An appropriate anesthetic agent should be chosen to minimize the interaction as well as side effects.

Lung Diseases

This medicine is not recommended for use in patients suffering from obstructive lung diseases such as bronchial asthma, bronchospasm, or Chronic Obstructive Pulmonary Disease since it may worsen the patient's condition. Replacement with a suitable alternative should be considered under your doctor's supervision.

Diabetes

This medicine should be used with caution in patients suffering from diabetes due to the increased risk of very low blood sugar levels. Close monitoring of blood sugar levels is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Sports

Athletes are advised to avoid participating in high-risk sports such as archery, racing, shooting, etc. during treatment with this medicine. Sportspersons should refer to the list of medicines published by World Anti-Doping Agency to get information about the prohibited substances.

Hyperthyroidism

This medicine should be administered with caution in patients suffering from hyperthyroidism since it may mask some of the patient's symptoms. Report any unusual symptoms to the doctor immediately. Close monitoring of thyroid hormone levels is recommended for such patient. Replacement with a suitable alternative may be required based on the clinical condition.

Aortic stenosis

This medicine should be used with extreme caution in patients suffering from aortic stenosis due to the increased risk of a very low blood pressure. Close monitoring of blood pressure is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Coronary artery diseases

This medicine should be used with caution in patients with coronary artery diseases since it may worsen the patient's condition. Abrupt withdrawal of this medicine may also worsen the symptoms of such patients, especially after prolonged use. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.

Impaired liver function

This medicine should be used with caution in patients suffering from liver diseases due to the increased risk of serious adverse effects. Close monitoring of liver function is recommended during treatment with this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Pediatric use

This medicine is not recommended for use in children since the safety and efficacy of use are not clinically established.

Impaired renal function

This medicine should be used with caution in patients suffering from kidney diseases due to the increased risk of serious adverse effects. Close monitoring of kidney function is recommended during treatment with this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, lightheadedness, irregular heart rate, and fainting. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
Interaction with Medicine

Alprazolam

Carbamazepine

Itraconazole

Corticosteroids

Rifampicin

Theophylline

Disease interactions

Lung disease

This medicine is not recommended for use in patients suffering from obstructive lung diseases such as bronchial asthma, bronchospasm, or Chronic Obstructive Pulmonary Disease since it may worsen the patient's condition. Replacement with a suitable alternative should be considered under your doctor's supervision.

Heart Block

This medicine is not recommended for use in patients with a heart block greater than the first degree since it may worsen the patient's condition. Replacement with a suitable alternative should be done under your doctor's supervision.

Glaucoma

This medicine should be administered with caution in patients suffering from glaucoma. A change in the dose of the current glaucoma medicine may be required in some cases. Replacement with a suitable alternative may be necessary based on the clinical condition.

Cardiogenic shock

This medicine is not recommended for use in patients suffering from a cardiogenic shock since it may worsen the patient's condition.
Food interactions
Consumption of grapefruit juice is not recommended during treatment with this medicine due to the increased risk of severe adverse effects such as dizziness, headache, swelling of hands and feet, etc.
Lab interactions
Information not available.
Take this medicine as advised by your doctor. It can be taken with or without food. Do not take in larger amounts than prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Amlodipine relaxes the heart muscles and the blood vessels. Bisoprolol relaxes the blood vessels and reduces the heart rate, promoting a smooth flow of the blood. Their combination is thus effective in reducing the blood pressure.
Legal Status

Approved

Unknown

Approved

Unknown

Classification

Category

Antihypertensive combinations, Cardioselective beta blockers with calcium channel blocker

Schedule

Schedule H

Bisoprolol: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 3 October 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a693024.html

Bisoprolol - DrugBank [Internet]. Drugbank.ca. 2017 [cited 3 October 2017]. Available from:

https://www.drugbank.ca/drugs/DB00612

ConcorAM - Merck Biopharma India [Internet]. Merckserono.in. 2017 [cited 3 October 2017]. Available from:

http://www.merckserono.in/en/therapy_areas/cardio_vascular_diseases/concor_concor_cor/concor_am/concor_am.html

DailyMed - Amlodipine besylate tablet [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 3 October 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b52e2905-f906-4c46-bb24-2c7754c5d75b

Amlodipine - DrugBank [Internet]. Drugbank.ca. 2017 [cited 3 October 2017]. Available from:

https://www.drugbank.ca/drugs/DB00381
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