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Combinase FT Nasal Spray

Manufactured byGerman Remedies Ltd
ContainsFluticasone furoate (27.5 mcg) + Azelastine (140 mcg)
Description

Combinase FT Nasal Spray is a combination medicine which is used to relieve moderate to severe symptoms such as sneezing, nasal congestion, runny nose, etc. associated with allergic rhinitis in adults and adolescents aged 12 years and above.

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Side effects

Major & minor side effects for Combinase FT Nasal Spray

  • Bitter taste
  • Burning in the Nose
  • Drowsiness or sleepiness
  • Sneezing
  • Headache
  • White patches in the nose
  • Cough
  • Unusual tiredness and weakness
  • Blurred vision

Uses of Combinase FT Nasal Spray

What is it prescribed for?

  • Allergic Rhinitis
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time taken by this medicine to show its effect is subject to vary based on the individual constitution.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains effective is subject to vary based on the individual constitution.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of severe side effects. These side effects may include confusion, dizziness, nausea, vomiting, weakness, fainting, etc. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine. If the medicine is used, the infant should be monitored closely for any undesired side effects.

Allergy

This medicine is not recommended for use in patients with a known allergy to fluticasone, azelastine, any other corticosteroids, or any other inactive ingredients present in the formulation.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine. If the medicine is used, the infant should be monitored closely for any undesired side effects.
General warnings

Driving or operating machinery

Use of this medicine may cause symptoms such as blurred vision, drowsiness, sleepiness, etc. in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Use in children

This medicine is not recommended for use in patients less than 12 years of age since the safety and efficacy of use are not clinically established.

Growth retardation

This medicine may cause growth retardation in some children. Therefore, children receiving this medicine should be monitored closely with regard to growth parameters. The dose should be titrated to the minimum effective dose to reduce the chances of such side effects. Replacement with a suitable alternative may be necessary in some cases based on the clinical condition.

Visual disturbances

This medicine may cause blurred vision or other visual disturbances in some patients. Report any such symptoms to the doctor immediately. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Nosebleed and nasal ulceration

This medicine may cause nosebleeds and nasal ulcerations in some patients. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Candida infection

Patients using this medicine for extended periods of time should be examined for candida infection or any other signs of adverse effects on the nasal and oral mucosa. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Impaired wound healing

This medicine is not recommended for use in patients who have experienced recent nasal trauma, nasal septal ulcers, nasal surgery, etc. until complete healing has occurred since this medicine may delay healing and worsen the patient's condition.

Missed Dose

Use the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Nasal

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of severe side effects. These side effects may include confusion, dizziness, nausea, vomiting, weakness, fainting, etc. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
Interaction with Medicine

Amitriptyline

Indinavir

Alprazolam

Buspirone

Aripiprazole

Carbamazepine

Clarithromycin

Ketoconazole

Brompheniramine

Disease interactions

Hyperadrenocorticism

This medicine should be used with caution in patients having a high level of adrenal hormones in the body due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Infections

This medicine should be used with extreme caution in patients with latent or active infections since this medicine can suppress the immune system and worsen the patient's condition. This risk is especially higher in patients on high doses of this medicine for a prolonged period of time. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Ocular herpes infection

This medicine should be used with caution in patients with an ocular herpes infection due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Ocular Toxicities

This medicine should be used with extreme caution in patients with a history of cataracts, glaucoma, or increased intraocular pressure due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Osteoporosis

This medicine should be used with caution in patients with osteoporosis since this medicine may cause loss of bone density and further worsen the existing condition. Close monitoring of bone density, appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Hepatic impairment

This medicine should be used with caution in patients with liver impairment due to the increased risk of severe adverse effects. Close monitoring of liver function may be required during treatment with this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.
Food interactions
Information not available.
Lab interactions
Information not available.
Use this medicine exactly as advised by your doctor. Do not use in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine inhibits the actions of certain chemical substances which are responsible for causing allergic symptoms.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Nasal antihistamines and decongestants, Nasal steroids

Schedule

Schedule H

[Internet]. CiplaMed. 2018 [cited 22 August 2018]. Available from:

https://ciplamed.com/content/furamist-az-nasal-spray

Fluticasone furoate - DrugBank [Internet]. Drugbank.ca. 2018 [cited 22 August 2018]. Available from:

https://www.drugbank.ca/drugs/DB08906

[Internet]. Accessdata.fda.gov. 2018 [cited 22 August 2018]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/022051lbl.pdf

Azelastine Nasal Spray: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2018 [cited 31 July 2018]. Available from:

https://medlineplus.gov/druginfo/meds/a697014.html
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Information on this page was last updated on 13 Jun 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.