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Combihale FF 250 Inhaler

Manufactured byDr. Reddys Laboratories Ltd.
ContainsFluticasone propionate (250 mcg) + Formoterol (6 mcg)
Description
Combihale FF 250 Inhaler is a combination of Fluticasone Propionate and Formoterol. It is used in the maintenance treatment of asthma (a condition that causes narrowing of the airways) and chronic obstructive pulmonary disease (lung conditions that cause blockage of airflow, leading to breathing difficulty). It works by relaxing and widening the muscles in your airways and making it easier to breathe. Combihale FF 250 Inhaler may cause some side effects like sore throat, cough, headache, and hoarse voice. Inform your doctor if these side effects persist or become severe. Combihale FF 250 Inhaler should be used in the dose and duration prescribed by your doctor. For the ease of remembering, use it around the same time every day. Even if you see an improvement in your condition, do not stop using it. If you discontinue this medicine early, your symptoms may reoccur. It should not be used to relieve sudden asthma attacks. Combihale FF 250 Inhaler should not be used if you are allergic to it. Inform your doctor if you have liver, or heart problems diabetes, active infections, or other medical conditions. Consult your doctor if you are pregnant, planning a pregnancy, or are breastfeeding. This medicine should not be used in children below 12 years of age.

Side effects

Major & minor side effects for Combihale FF 250 Inhaler

  • Headache
  • Irregular heartbeat
  • Dizziness
  • Dry mouth
  • Sore throat
  • Rash
  • Muscle spasm
  • Unusual tiredness or weakness
  • Swelling of ankles or feet

Uses of Combihale FF 250 Inhaler

What is it prescribed for?

  • Asthma
  • Chronic obstructive pulmonary disease
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for Combihale FF 250 Inhaler to show its effect is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which Combihale FF 250 Inhaler remains active in your body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Combihale FF 250 Inhaler.
  • Can this medicine be taken during pregnancy?
    Combihale FF 250 Inhaler is not recommended for use in pregnancy unless necessary. Hence, consult your doctor before using this medicine.
  • Can this medicine be taken while breast-feeding?
    Combihale FF 250 Inhaler is not recommended for use while breastfeeding unless necessary. Hence, consult your doctor before using this medicine.

Allergy

Avoid using Combihale FF 250 Inhaler if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (of your face/tongue/throat), breathing difficulty, etc.

Status asthmaticus

Status asthmaticus is a severe form of asthma that is sudden and does not respond to standard treatments. These attacks can last for several minutes or even hours. Combihale FF 250 Inhaler is not recommended for use if you have status asthmaticus as it is not effective in treating this condition.
Warnings for special population

Pregnancy

Combihale FF 250 Inhaler is not recommended for use in pregnancy unless necessary. Hence, consult your doctor before using this medicine.

Breast-feeding

Combihale FF 250 Inhaler is not recommended for use while breastfeeding unless necessary. Hence, consult your doctor before using this medicine.
General warnings

Hypokalaemia

Combihale FF 250 Inhaler may cause a decrease in blood potassium levels and lead to heart-related complications. Hence this medicine should be used with caution if you have hypokalaemia (low blood potassium levels).

Tuberculosis

Combihale FF 250 Inhaler should be used with caution if you have tuberculosis (lung infection) due to the increased risk of worsening of your condition.

Use in children

Combihale FF 250 Inhaler is not recommended for use in children less than 12 years of age as the safety and efficacy data are not clinically established.

Seizures

Combihale FF 250 Inhaler should be used with caution if you have a history of seizures (fits) as it may further worsen your condition.

Missed Dose

If you miss a dose of Combihale FF 250 Inhaler, administer the missed dose as soon as you remember. If it is time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Seek emergency medical treatment in case of an overdose of Combihale FF 250 Inhaler.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Amitriptyline

Amprenavir

Itraconazole

Clarithromycin

Labetalol

Theophylline

Disease interactions

Cardiovascular disorders

Combihale FF 250 Inhaler should be used with caution if you have problems related to the heart and blood vessels. This medicine may cause an irregular heart rhythm, increased heartbeat, blood pressure changes, etc., leading to further complications.

Infections

Combihale FF 250 Inhaler should be used with caution as it may suppress the activity of the immune system and increase the risk of infections of the mouth and throat.

Hepatic impairment

Combihale FF 250 Inhaler should be used with caution if you have liver problems due to the increased risk of severe side effects. Your doctor may suggest tests to monitor your liver functions during treatment with this medicine.

Hyperadrenocorticism

Hyperadrenocorticism is a condition that occurs due to high levels of cortisol hormone (a chemical substance that helps your body respond to stress, regulate blood sugar, and fight infections) in the body. High doses of Combihale FF 250 Inhaler for prolonged time should be used with caution as it may cause or worsen hyperadrenocorticism, in rare cases.

Ocular Toxicities

Prolonged use of high doses of Combihale FF 250 Inhaler may cause cataracts (clouding of the lens of the eye) or increased fluid pressure inside the eye. Hence it should be used with caution if you have a history of cataracts or glaucoma (an eye condition with abnormally high pressure inside the eye that may lead to vision loss).

Osteoporosis

Osteoporosis is a condition of weak and brittle bones. Combihale FF 250 Inhaler should be used with caution if you have osteoporosis as it may decrease bone mineral density and weaken your bones.

Diabetes

Combihale FF 250 Inhaler should be used with caution if you have diabetes (increased blood sugar levels) as it may further increase the risk of elevated blood sugar levels. Check your blood sugar levels regularly while you are using this medicine.
Food interactions
Information not available.
Lab interactions
Information not available.
Administer Combihale FF 250 Inhaler as prescribed by your doctor. Follow all the instructions given on the information leaflet or the package insert. Do not use in larger or smaller amounts than prescribed. Do not stop the use of this medicine without consulting your doctor as it may worsen your condition. Consult your doctor if you experience any undesirable effects that persist or worsen. Combihale FF 250 Inhaler is not effective in treating an asthma attack that has already started. Always use a rescue inhaler to treat such symptoms.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Effect on sleep is not established

How it works
Combihale FF 250 Inhaler is a combination of Fluticasone Propionate and Formoterol. Fluticasone propionate works by inhibiting the release of certain substances in the body that cause inflammation (swelling, redness, pain, etc.). Formoterol relaxes and widens the blocked air passages leading to the lungs. This improves the amount of airflow to the lungs and makes breathing easier.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Inhaled corticosteroids, Adrenergic bronchodilators

Schedule

Schedule H

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Drugs, H., 2021. Fluticasone Oral Inhalation: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 6 December 2021].

https://medlineplus.gov/druginfo/meds/a601056.html>

CiplaMed. 2021. MAXIFLO Inhaler. [online] Available at: < [Accessed 20 December 2021].

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Drugs, H., 2021. Formoterol Oral Inhalation: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 20 December 2021].

https://medlineplus.gov/druginfo/meds/a602023.html>
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Information on this page was last updated on 11 Jan 2022

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