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Colgin Plus Tablet

Manufactured byMEDOPHARM PVT LTD
ContainsParacetamol (500 mg) + Phenylephrine (10 mg) + Chlorpheniramine (2 mg) + Caffeine (Anhydrous) (30 mg)
Description

Colgin Plus Tablet is a combination medicine which may be used to relieve nasal congestion, excess production of mucus, runny nose, headache, fever, etc. associated with the common cold, upper respiratory tract allergies, etc.

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Side effects

Major & minor side effects for Colgin Plus Tablet

  • Nausea or Vomiting
  • Gastric / Mouth Ulcer
  • Chills
  • Sleepiness or unusual drowsiness
  • Dry mouth
  • Jaundice
  • Increase in the blood pressure
  • Difficult or painful urination

Uses of Colgin Plus Tablet

What is it prescribed for?

  • Common Cold
  • Upper respiratory tract allergies
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of this medicine can be observed within 30 to 60 minutes of administration of the dose.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol during treatment with this medicine may increase the risk of severe side effects. These side effects may include confusion, dizziness, nausea, vomiting, weakness, and fainting. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you consume alcohol while taking this medicine.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. If the medicine is used, the infant should be monitored closely for any undesired side effects.

Allergy

This medicine is not recommended for use in patients with a known allergy to paracetamol, phenylephrine, chlorpheniramine, caffeine, or any other inactive ingredients present in the formulation.

Analgesic Nephropathy (Kidney Disease)

This medicine is not recommended for use in patients suffering from kidney diseases associated with the excessive use of painkillers due to the increased risk of worsening the patient's condition.

Severe liver impairment

This medicine is not recommended for use in patients with severe liver diseases due to the increased risk of worsening the patient's condition.

Benign prostatic hyperplasia

This medicine is not recommended for use in patients with benign prostatic hyperplasia (enlarged prostate) since it may cause increased difficulty in passing urine.

Monoamine oxidase inhibitors (MAOI)

Use of this medicine is not recommended if the patient has taken MAO inhibitors like selegiline or rasagiline within the last 14 days. Their combination may increase the risk of adverse effects like drowsiness and blurred vision.

Hypertension

This medicine is not recommended for use in patients with severe hypertension due to the increased risk of worsening the patient's condition.

Ventricular tachycardia

This medicine is not recommended for use in patients with ventricular tachycardia due to the increased risk of worsening the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. If the medicine is used, the infant should be monitored closely for any undesired side effects.
General warnings

Liver Disease

This medicine should be used with extreme caution in patients suffering from liver function impairment or active liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Chronic Malnutrition

This medicine should be used with extreme caution in patients suffering from malnourishment due to the increased risk of severe adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Kidney Disease

This medicine should be used with caution in patients with kidney impairment due to the increased risk of worsening of the patient's condition. Regular monitoring of kidney function, appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Epilepsy

This medicine should be used with caution in patients with epilepsy since it increases the risk of seizures. An alternative treatment option may be necessary in some cases based on the clinical condition.

Driving or Operating machinery

Use of this medicine may cause blurred vision or dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol during treatment with this medicine may increase the risk of severe side effects. These side effects may include confusion, dizziness, nausea, vomiting, weakness, and fainting. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you consume alcohol while taking this medicine.
Interaction with Medicine

Carbamazepine

Linezolid

Phenytoin

Sodium Nitrite

Leflunomide

Prilocaine

Antidiabetic drugs

Antidepressants

Beta blockers

Anxiolytics

Duloxetine

Theophylline

Disease interactions

Cardiovascular disorders

This medicine is not recommended for use in patients with a known history of serious cardiac disorders such as severe hypertension, coronary artery disease, heart failure, etc. due to the increased risk of worsening of the patient's condition. Replacement with a suitable alternative should be considered based on the clinical condition.

Liver Disease

This medicine is not recommended for use in patients with a known history of severe liver impairment due to the increased risk of worsening of the patient's condition. In patients with mild to moderate liver diseases, the medicine should be used with caution. Close monitoring of liver function tests, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.

Seizures

This medicine should be used with extreme caution in patients with a known history of seizures due to the increased risk of recurrent seizures. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Peptic ulcer disease

This medicine should be used with extreme caution in patients with peptic ulcer disease due to the increased risk of worsening of the patient's condition. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Gastrointestinal blockage

This medicine is not recommended for use in patients with a gastrointestinal obstruction due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Asthma

This medicine is not recommended for use in patients with asthma/COPD since it may increase the risk of further lung problems like respiratory tract blockage. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Diabetes

This medicine should be used with caution in patients with diabetes due to the increased risk of high blood sugar levels. Close monitoring of blood glucose levels is recommended while using this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Food interactions
Information not available.
Lab interactions

5-HIAA Urine Test

You may get a false-positive result for this test while taking this medicine. It is advised that you inform the doctor and lab technician about all your current medicines including herbs and supplements before undergoing any lab tests.
Take this medicine as advised by your doctor. You may take this medicine with or without food. Do not take more than what is prescribed or share this medication with other people. It is advised that you should inform the doctor about all the medicines or herbal products that you are using as well as about all your medical conditions before taking this medicine.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Paracetamol increases the pain threshold and decreases swelling. It also brings down elevated body temperature by acting on heat regulatory centers in the brain. Phenylephrine acts by reducing the swelling of the blood vessels in the nasal passages, making it easier to breathe. Chlorpheniramine blocks the action of certain substances produced by the body which induce allergic reactions. Caffeine helps patients experiencing drowsiness and fatigue to stay alert and awake.
Legal Status

Banned

Unknown

Unknown

Unknown

Classification

Category

Upper respiratory combinations, CNS stimulants

Schedule

Schedule H

[Internet]. Centaurpharma.com. 2019 [cited 3 April 2019]. Available from:

https://www.centaurpharma.com/downloads/Sinarest%20Tab.pdf

Caffeine - DrugBank [Internet]. Drugbank.ca. 2018 [cited 28 March 2018]. Available from:

https://www.drugbank.ca/drugs/DB00201

Chlorphenamine - DrugBank [Internet]. Drugbank.ca. 2017 [cited 11 July 2017]. Available from:

https://www.drugbank.ca/drugs/DB01114

Phenylephrine: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 18 July 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a606008.html

Acetaminophen | C8H9NO2 - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2017 [cited 22 February 2017]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/1983#section=Top
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Information on this page was last updated on 30 Jul 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.