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Cofdex P Syrup

Manufactured byCipla Ltd.
ContainsDextromethorphan (5 mg/5 ml) + Phenylephrine (5 mg/5 ml) + Bromhexine (4 mg/5 ml)
Description

Cofdex P Syrup is a combination medicine which may be used for the treatment of a cough that produces mucus or phlegm. It may also be used to treat conditions with an abnormal mucus secretion, allowing the patient to breathe freely and deeply.

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Side effects

Major & minor side effects for Cofdex P Syrup

  • Confusion
  • Constipation
  • Dizziness
  • Drowsiness
  • Headache
  • Nausea or Vomiting
  • Blurred or double vision
  • Dry mouth

Uses of Cofdex P Syrup

What is it prescribed for?

  • Productive cough
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of this medicine can be observed within 15-30 minutes of administration of the dose.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended while taking this medicine since it may increase the risk of side effects like confusion, dizziness, and impaired judgment. Avoid performing activities that need high mental alertness like driving a vehicle or operating machinery if alcohol and this medicine are used together.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to dextromethorphan, phenylephrine, bromhexine or any other inactive ingredients present in the formulation.

Hypertension

This medicine is not recommended for use in patients with severe hypertension due to the increased risk of worsening of the patient's condition.

Ventricular tachycardia

This medicine is not recommended for use in patients with ventricular tachycardia due to the increased risk of worsening of the patient's condition.

Monoamine oxidase inhibitors (MAOI)

This medicine is not recommended for use in patients taking monoamine oxidase inhibitors (MAOI) due to the increased risk of serious and life-threatening side effects. A time gap of at least 14 days should be maintained between stopping therapy with MAOIs and starting therapy with this medicine.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Other medicines

This combination medicine may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Liver/Kidney Disease

This medicine should be used with caution in patients with kidney/liver diseases due to the increased risk of adverse effects. Close monitoring of kidney/liver function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Driving or Operating machinery

Use of this medicine may cause blurred vision or dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Use in Children

This medicine is not recommended for use in children below 4 years of age since the safety and efficacy of use are not clinically established.

Gastric ulceration

This medicine is not recommended for use in patients with a known history of gastric ulceration or any other gastrointestinal disorders due to the increased risk of worsening of the patient's condition. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Missed Dose

Take/Administer the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended while taking this medicine since it may increase the risk of side effects like confusion, dizziness, and impaired judgment. Avoid performing activities that need high mental alertness like driving a vehicle or operating machinery if alcohol and this medicine are used together.
Interaction with Medicine

Escitalopram

Metoclopramide

Ondansetron

Antidiabetic drugs

Alprazolam

Isocarboxazid

Perphenazine

Disease interactions

Psychiatric Conditions

This medicine should be used with caution in patients with psychiatric conditions due to an increased risk of confusion and hallucinations. An alternative treatment option should be considered based on the clinical condition.

Cardiovascular disease

This medicine should be used with extreme caution in patients with cardiovascular diseases due to the increased risk of side effects. Report any incidence of irregular heart rate and very high blood pressure to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Benign prostatic hyperplasia

This medicine should be used with caution in patients with an enlarged prostate due to the risk of increased difficulty in passing urine. Report any worsening of symptoms to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Diabetes

This medicine should be used with caution in patients with diabetes due to the increased risk of high blood sugars. Close monitoring of blood glucose levels is recommended while using this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Take/Administer this medicine exactly as prescribed by your doctor. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Causes sleepiness

How it works
Dextromethorphan blocks the signals from the brain that trigger cough reflex and thus it helps in suppressing the cough. Phenylephrine acts by reducing the swelling of the blood vessels in the nasal passages, making it easier to breathe. Bromhexine works by thinning the mucus in the airway and promoting mucus clearance.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Antitussives, Mucolytics, Decongestants

Schedule

Schedule H

Dextromethorphan - DrugBank [Internet]. Drugbank.ca. 2017 [cited 11 July 2017]. Available from:

https://www.drugbank.ca/drugs/DB00514

[Internet]. 2017 [cited 18 July 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/11868

[Internet]. Tga.gov.au. 2018 [cited 5 April 2018]. Available from:

https://www.tga.gov.au/sites/default/files/otc-medicine-monograph-bromhexine-hydrochloride.pdf
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Information on this page was last updated on 24 Jul 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.