Co-Dergocrine Mesylate

Description

Co-Dergocrine Mesylate is an ergot alkaloid, which is used to relieve the signs and symptoms of age-related cognitive impairment in patients with dementia related to aging or associated with Alzheimer's disease, a condition in which the patient's memory and ability to think, communicate, learn, and handle daily activities are impaired slowly. This medicine is not recommended for use in children.

Side effects

Major & minor side effects for Co-Dergocrine Mesylate

  • Dizziness
  • Lightheadedness
  • Drowsiness
  • Skin rash
  • Slow heart rate
  • Blurred vision
  • Flushing
  • Loss of appetite
  • Nausea and Vomiting
  • Stomach cramps
  • Stuffy nose
  • Fainting

Uses of Co-Dergocrine Mesylate

What is it prescribed for?

  • Dementia
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Concerns

Commonly asked questions

  • Onset of action
    The effect of this medicine can be observed within 3 to 4 weeks of administration of the dose.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking/receiving this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking/receiving this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to Co-Dergocrine Mesylate or any other components present along with it.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking/receiving this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking/receiving this medicine.
General warnings

Kidney impairment

This medicine should be used with caution in patients suffering from kidney diseases due to the increased risk of adverse effects. Close monitoring of kidney function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Liver impairment

This medicine should be used with extreme caution in patients suffering from liver impairment due to the increased risk of severe adverse effects. Close monitoring of liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Use in elderly population

This medicine should be used with extreme caution in the elderly population due to the increased risk of severe adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Use in children

This medicine is not recommended for use in patients below 18 years of age since the safety and efficacy of use are not clinically established.

Driving or operating machinery

This medicine may cause dizziness, blurred vision, or drowsiness in some patients. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Other medicines

Co-Dergocrine Mesylate may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Missed Dose

Oral form: Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose. Injection: Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low.

Overdose

Oral form: Seek emergency medical treatment or contact the doctor in case of an overdose. Injection: Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of an overdose is very low. However, emergency medical treatment will be instituted by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Disease interactions

Psychosis

This medicine is not recommended for use in patients with acute or chronic psychosis due to the risk of worsening of the patient's condition. An alternative treatment option should be considered based on the clinical condition.

Cardiovascular diseases

This medicine should be used with extreme caution in patients with severe cardiovascular diseases due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Oral form: Take this medicine exactly advised by your doctor. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable effects. Do not stop taking this medicine before completion of the course/without consulting your doctor. Injection: This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Causes sleepiness

How it works
This medicine decreases the abnormal activity in the brain and helps in improving the symptoms of declined mental capacity.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Ergoloid Derivatives, Miscellaneous central nervous system agents

Schedule

Schedule H

Ergoloid mesylate - DrugBank [Internet]. Drugbank.ca. 2018 [cited 24 December 2018]. Available from:

https://www.drugbank.ca/drugs/DB01049

Ergoloid Mesylates [Internet]. Pubchem.ncbi.nlm.nih.gov. 2018 [cited 24 December 2018]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/592735

ErgoloMesylates: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2018 [cited 24 December 2018]. Available from:

https://medlineplus.gov/druginfo/meds/a682097.html

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Information on this page was last updated on 23 May 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.