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Clotnine 600 IU Injection

Manufactured byHEMARUS THERAPEUTICS LTD
Description

Clotnine 600 IU Injection helps in the clotting of blood and prevents bleeding. The genetic condition with Coagulation Factor IX deficiency is called Hemophilia B which is characterized by the inability of the body to control bleeding. Clotnine 600 IU Injection is used for the control and prevention of bleeding episodes in adults and pediatric patients with Hemophilia B or Christmas disease and acquired Factor IX deficiency.

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Side effects

Major & minor side effects for Clotnine 600 IU Injection

  • Allergic reactions
  • Anxiety
  • Low blood pressure
  • Headache and dizziness
  • Difficulty in breathing
  • Injection site pain

Uses of Clotnine 600 IU Injection

What is it prescribed for?

  • Hemophilia B
  • Factor IX Deficiency
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time taken by this medicine to show its effect is not clinically well established.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. Your doctor will determine the best course of treatment after assessing the condition and evaluating the risks and benefits associated with the use of this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

Allergy

This medicine is not recommended for use if you have a known history of allergy to this medicine or any other inactive ingredients present in the medicine.

Disseminated intravascular coagulation

This medicine is not recommended for use in patients with disseminated intravascular coagulation (a serious condition in which blood clots forms throughout the bloodstream) due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. Your doctor will determine the best course of treatment after assessing the condition and evaluating the risks and benefits associated with the use of this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.
General warnings

Severe allergic reactions

Severe allergic reactions or hypersensitivity reactions, including anaphylactic shock, low blood pressure, breathing difficulties, urticaria (skin rash), etc. may occur with this medicine. If symptoms of allergic reactions occur, discontinue immediately and initiate appropriate treatment.

Neutralizing antibodies

Prolonged use of this medicine may cause antibodies that inhibit the desired effect of this medicine. Any such antibody development leads to severe allergic reactions. Close monitoring is necessary.

Thromboembolism

Formation of dangerous clots and related complications may occur with this medicine. Close monitoring of symptoms for thrombotic events is necessary.

Other medicines

Clotnine 600 IU Injection may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Missed Dose

Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low.

Overdose

Contact your doctor immediately and seek emergency medical help in case of an overdose of this medicine.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Carfilzomib

Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Your dose regimen and frequency of administration is likely to vary based on the condition being treated. Consult your doctor immediately if you develop any signs and symptoms of an allergy.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Effect on sleep is not established

How it works
This medicine works by promoting the formation of certain proteins that form blood clots and prevent bleeding.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Miscellaneous coagulation modifiers

Schedule

Schedule H

[Internet]. Medicines.org.uk. 2019 [cited 4 January 2019]. Available from:

https://www.medicines.org.uk/emc/product/580/smpc

[Internet]. Hemarus.co.in. 2019 [cited 27 August 2019]. Available from:

http://hemarus.co.in/downloads/clotninie-inserts.pdf

[Internet]. Ebs.tga.gov.au. 2019 [cited 4 January 2019]. Available from:

https://www.ebs.tga.gov.au/ebs/picmi/picmirepository.nsf/pdf?OpenAgent&id=CP-2014-PI-03090-1

Coagulation Factor IX (Recombinant) - DrugBank [Internet]. Drugbank.ca. 2019 [cited 4 January 2019]. Available from:

https://www.drugbank.ca/drugs/DB00100
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Information on this page was last updated on 27 Aug 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.