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Clofranil 10 MG Tablet

Manufactured bySun Pharma Laboratories Ltd.
ContainsClomipramine
Description

Clofranil 10 MG Tablet is a tricyclic antidepressant medicine, used for the treatment of depression and obsessive-compulsive disorder and phobia. It is also used in the treatment of muscle weakness associated with the sleep disorder called narcolepsy. Take this medicine at the same time regularly. Do not stop taking this medicine suddenly without informing your doctor as it may cause withdrawal symptoms.

Side effects

Major & minor side effects for Clofranil 10 MG Tablet

  • Dizziness
  • Blurred vision
  • Dry mouth
  • Nausea or Vomiting
  • Swelling of face and feet
  • Acid or sour stomach
  • Constipation
  • Shaking of hands or feet
  • Mouth ulcers
  • Irregular menstrual periods

Uses of Clofranil 10 MG Tablet

What is it prescribed for?

  • Obsessive Compulsive Disorder
  • Depression
  • Cataplexy associated with narcolepsy
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as difficulty concentrating and dizziness. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
  • Is this a habit forming medicine?
    No habit forming tendency has been reported
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine. If the medicine is taken, the infant should be monitored closely for any undesired side effects.

Allergy

This medicine is not recommended for use in patients with a known allergy to clomipramine or any other inactive ingredients present in the formulation.

Monoamine oxidase inhibitors (MAOI)

This medicine is not recommended for use while an MAOI medicine (Rasagiline/Selegiline/methylene blue etc.) is being consumed. This medicine should be consumed at least 14 days after stopping the use of MAOI medicines.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine. If the medicine is taken, the infant should be monitored closely for any undesired side effects.
General warnings

Suicidal thoughts

This medicine should be used with caution due to the increased risk of suicidal thoughts. Close monitoring of the patients for any change in behavior or mood is recommended. Appropriate dose adjustments or replacement with a suitable alternative may be necessary in some cases based on the clinical condition.

Serotonin Syndrome

This medicine may cause potentially life-threatening serotonin syndrome. Immediate medical treatment should be initiated if any symptoms of agitation, hallucinations, dizziness, tremor, seizures, nausea, and vomiting appear.

Effect on heart

This medicine may lower the blood pressure, therefore should be used with caution in patients with heart diseases. Close monitoring of blood pressure is necessary. Inform the doctor if any symptoms such as dizziness, lightheadedness appear.

Changes in weight

This medicine is known to cause either weight loss or weight gain. Inform the doctor if you experience any changes in body weight. Close monitoring of body weight is recommended during treatment with this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be necessary in some cases based on the clinical condition.

Withdrawal Symptoms

This medicine may cause withdrawal symptoms if the usage is stopped abruptly. This risk is especially higher after prolonged usage of this medicine. The treatment should be withdrawn gradually under the close supervision of your doctor. Do not stop the use of this medicine without consulting your doctor.

Driving or operating machinery

This medicine may cause dizziness or drowsiness in some patients. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as difficulty concentrating and dizziness. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
Interaction with Medicine

Tramadol

Antihypertensives

Cetirizine

Metoclopramide

Minoxidil

Disease interactions

Seizures

This medicine should be used with caution in patients with a known history of seizures due to the increased risk of worsening of the patient's condition. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Diabetes

This medicine should be used with caution in patients with diabetes mellitus due to the increased risk of altered blood glucose levels. Close monitoring of blood sugar levels is recommended for such patients. Replacement with a suitable alternative may be necessary in some cases based on the clinical condition of the patient.

Glaucoma

This medicine should be used with caution in patients with a known history of glaucoma due to the increased risk of worsening of the patient's condition. Replacement with a suitable alternative should be considered based on the clinical condition of the patient.

Liver impairment

This medicine should be used with caution in patients with mild to moderate liver impairment due to the increased risk of severe adverse effects. Close monitoring of liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Kidney impairment

This medicine should be used with caution in patients with kidney impairment due to the increased risk of severe adverse effects. Close monitoring of kidney function tests, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine exactly as advised by the doctor. Do not take in larger amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

Causes sleepiness

How it works
This medicine works by increasing the levels of a chemical substance in the brain which helps in reducing the symptoms by maintaining the normal brain function.
Legal Status

Approved

Unknown

Approved

Unknown

Classification

Category

Tricyclic antidepressants

Schedule

Schedule H

Clomipramine: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2020 [cited 8 April 2020]. Available from:

https://medlineplus.gov/druginfo/meds/a697002.html

Clomipramine - DrugBank [Internet]. Drugbank.ca. 2020 [cited 8 April 2020]. Available from:

https://www.drugbank.ca/drugs/DB01242

[Internet]. Medsafe.govt.nz. 2020 [cited 8 April 2020]. Available from:

https://www.medsafe.govt.nz/profs/Datasheet/a/Apoclomipraminetab.pdf

[Internet]. Guildlink.com.au. 2020 [cited 8 April 2020]. Available from:

http://www.guildlink.com.au/gc/ws/nv/pi.cfm?product=nvpanfor10415

[Internet]. Guildlink.com.au. 2020 [cited 8 April 2020]. Available from:

http://www.guildlink.com.au/gc/ws/nv/cmi.cfm?product=nvcanfor10415

[Internet]. 2020 [cited 8 April 2020]. Available from:

https://deputyprimeminister.gov.mt/en/poyc/Documents/another/clomipramine.pdf
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Information on this page was last updated on 8 Jun 2020

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We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.