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Clobeta-GM Cream
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Clobeta-GM Cream

Manufactured byLABORATE PHARMACEUTICALS LTD
ContainsClobetasol (0.05 %w/w) + Miconazole (2 %w/w) + Neomycin (0.5 %w/w) + Zinc oxide (2.5 %w/w) + Borax (0.05 %w/w)
Description
Clobeta-GM Cream is a combination medicine which may be used for the treatment of steroid responsive dermatoses associated with superficial bacterial and fungal infections of the skin. This medicine is not recommended for use if you are known allergic to it.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Clobeta-GM Cream

  • Burning sensation at the application site
  • Dry skin
  • Redness of skin
  • Itching of skin
  • Skin irritation

Uses of Clobeta-GM Cream

What is it prescribed for?

  • Steroid responsive skin infections
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine. If the medicine is used, the infant should be monitored closely for any undesired side effects.

Allergy

This medicine is not recommended for use in patients with a known allergy to clobetasol, miconazole, neomycin, zinc oxide, borax or any other inactive ingredients present along with the formulation.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine. If the medicine is used, the infant should be monitored closely for any undesired side effects.
General warnings

Cushing's syndrome

This medicine may cause hypothalamic-pituitary-adrenal (HPA) axis suppression and Cushing's syndrome in patients receiving high doses for a prolonged period. Any symptoms of swelling of the face, increase in the blood glucose levels, etc. should be informed to the doctor on priority. Replacement with a suitable alternative may be necessary in some cases based on the clinical condition.

External use

This medicine is recommended for external use only. Avoid contact with the eyes, mucous membranes, or open wounds.

Other medicines

This medicine may interact with a large number of medications and may cause severe adverse effects. Hence, it is advised that you report the use of all your medicines including any herbs and supplements to the doctor before beginning therapy with this medicine.

Allergic reactions

This medicine has the potential of causing moderate to severe allergic reactions in the body. Any instance indicative of allergic reactions should be reported to the doctor in the first instance.

Liver and/or kidney impairment

If this medicine is applied over a large surface area for a prolonged period of time, there is a chance of systemic absorption. Hence this medicine should be used with caution in patients with liver and/or kidney impairment. Appropriate dosage adjustments or replacement with a suitable alternative may be necessary in some cases based on the clinical condition.

Missed Dose

Apply the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not apply a double dose to make up for the missed dose.

Overdose

An overdose of this medicine is not likely to cause severe symptoms. However, ingestion of this medicine may cause harm and immediate medical intervention may be required.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Warfarin

Antidiabetic drugs

Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Apply a thin layer of the cream to the affected area as instructed by the doctor. Follow all the usage instructions mentioned on the label or the package insert. Do not apply in larger or smaller quantities than recommended. Do not cover the application area with bandages or other coverings unless specifically instructed by the doctor. Contact your doctor if symptoms do not improve or resolve after two weeks of use.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works
Clobetasol works by inhibiting the release of certain substances in the body that cause inflammation (swelling, redness, pain, etc). Miconazole stops the growth of fungi by disrupting certain vital processes in the cell. Neomycin kills the bacteria by blocking the production of certain proteins that are required for their growth. Zinc oxide works by soothing the skin, preventing skin irritation, and helping in the healing process. Borax penetrates deep into the skin and helps to reduce bacteria located on the skin.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Topical steroids, Topical antifungals, Topical antibiotics

Schedule

Schedule H

Clobetasol: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 10 May 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a686008.html

Miconazole: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 28 March 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a601203.html

Miconazole - DrugBank [Internet]. Drugbank.ca. 2017 [cited 16 November 2017]. Available from:

https://www.drugbank.ca/drugs/DB01110

Neomycin - DrugBank [Internet]. Drugbank.ca. 2017 [cited 10 August 2017]. Available from:

https://www.drugbank.ca/drugs/DB00994

Neomycin Topical: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 13 August 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a682274.html
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Information on this page was last updated on 12 Jul 2019

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We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.