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Clobet GM Cream

Manufactured byBIOCHEM PHARMACEUTICAL INDUSTRIES LTD
ContainsClobetasol (0.05 %w/w) + Gentamicin (0.1 %w/w) + Miconazole (2 %w/w)
Description
Clobet GM Cream is used to treat skin infections responsive to steroids and where bacterial or fungal infections exist. It also helps to relieve redness, swelling, and itching associated with skin conditions such as psoriasis, eczema or ichthyosis. Clobet GM Cream may rarely cause burning, irritation, itching, and redness at the application site. These symptoms last only for a very few days and disappear with time. Do not use this cream if you are previously allergic to it. Apply a thin layer of Clobet GM Cream to the affected areas 1-2 times a day. Wash and dry the affected areas before application. Avoid contact with the eyes and mouth. Keep the affected area clean and dry because the presence of water can increase microbial growth. If the symptoms are not resolved within seven days, consult your doctor before continuing the treatment.

Side effects

Major & minor side effects for Clobet GM Cream

  • Skin rash
  • Redness of the skin
  • Blisters under the skin
  • Burning or tingling sensation of skin
  • Itchy and dry skin
  • Unusually warm skin
  • Lightening of skin at the area of application

Uses of Clobet GM Cream

What is it prescribed for?

  • Steroid responsive skin infections
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    You will start to see an improvement during the first few days of treatment with Clobet GM Cream. But finish your entire course of treatment, even if the condition gets better.
  • How long do the effects of this medicine last?
    The amount of time for which Clobet GM Cream remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Clobet GM Cream.
  • Can this medicine be taken during pregnancy?
    Although Clobet GM Cream is a topical preparation, use it in pregnant women only after a doctor's advise and prescription.
  • Can this medicine be taken while breast-feeding?
    Clobet GM Cream is not known to be harmful in breastfeeding women. Short-term application of this medicine may not cause any harm to the baby. All the benefits and risks should be discussed with the doctor before using it.

Allergy

Avoid using Clobet GM Cream if you are previously allergic to it. Serious allergic reactions to this medicine are very rare. However, seek immediate medical attention if you notice any symptoms of allergic reactions such as skin rash, hives, redness of the skin, itching, swelling of the face, lips, or tongue.
Warnings for special population

Pregnancy

Although Clobet GM Cream is a topical preparation, use it in pregnant women only after a doctor's advise and prescription.

Breast-feeding

Clobet GM Cream is not known to be harmful in breastfeeding women. Short-term application of this medicine may not cause any harm to the baby. All the benefits and risks should be discussed with the doctor before using it.
General warnings

Allergic reactions

Clobet GM Cream may rarely cause an allergic reaction in the body. Any instance indicative of allergic reactions should be reported to the doctor in the first instance.

External use

Clobet GM Cream is recommended for external use only. Avoid contact with the eyes, mucous membranes, or open wounds.

Cushing's syndrome

In some rare cases, treatment with Clobet GM Cream may cause hypothalamic-pituitary-adrenal (HPA) axis suppression and Cushing's syndrome in patients receiving high doses for a prolonged period. It can cause high blood pressure, swelling of the face, a rise in blood glucose levels, weight gain, increased hair growth or change in the skin tone. Any such symptoms should be informed to the doctor on priority.

Missed Dose

Apply the missed dose of Clobet GM Cream as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not apply a double dose to make up for the missed dose.

Overdose

An overdose of Clobet GM Cream is not likely to cause severe symptoms unless it is applied for a prolonged period of time in large volumes. However, ingestion of this medicine may cause harm and immediate medical intervention may be required.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
Apply a thin layer of Clobet GM Cream to the affected area as instructed by the doctor. Finish your entire course of treatment even if your symptoms begin to clear up after a few days. If the symptoms are not resolved within seven days, consult your doctor before continuing the treatment.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works
Clobetasol is a topical steroid that prevents the production of prostaglandins- the substance that causes redness, itching and swelling. Gentamicin works by preventing the formation of bacterial cell walls. This helps in stopping the growth and multiplication of the microorganism, eventually killing it. Miconazole kills the fungus by stopping their cell wall formation. It works by preventing the fungi from making a substance called ergosterol, which is necessary for the production of the cell wall.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Topical steroids with anti-infectives, Topical antifungals, Topical antibiotics

Schedule

Schedule H

Drugbank.ca. 2021. Clobetasol | DrugBank Online. [online] Available at: < [Accessed 27 April 2021].

https://www.drugbank.ca/drugs/DB11750>

Drugbank.ca. 2021. Gentamicin | DrugBank Online. [online] Available at: < [Accessed 27 April 2021].

https://www.drugbank.ca/drugs/DB00798>

Drugbank.ca. 2021. Miconazole | DrugBank Online. [online] Available at: < [Accessed 27 April 2021].

https://www.drugbank.ca/drugs/DB01110>

Drugs, H., 2021. Clobetasol Topical: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 27 April 2021].

https://medlineplus.gov/druginfo/meds/a686008.html>
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Information on this page was last updated on 1 May 2021

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