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Clip 500 MG Injection

Manufactured byFdc Ltd.
Description
Clip 500 MG Injection is an anti-fibrinolytic medicine (a medicine used for clotting of blood) containing Tranexamic acid. It is used in the treatment of uncontrollable bleeding conditions that are seen after tooth extraction, in menstruation, haemorrhage (the release of blood from a broken blood vessel), angioedema (painless swelling under the skin), etc. Clip 500 MG Injection works by slowing the blood clotting and this action prevents loss of blood. It is one of the safest medicines that are used to control bleeding. Clip 500 MG Injection may cause side effects such as pain in the chest, cough, shortness of breath, swelling of limbs, fatigue, pain at the site of injection, etc. Consult your doctor if any of these side effects persist or worsen. Inform your doctor if you are allergic to Clip 500 MG Injection. Avoid driving vehicles or doing activities that require your concentration after taking this medicine as it may cause dizziness or drowsiness. Clip 500 MG Injection should be administered into your vein by a health care professional in a hospital. Do not self administer. The dose will be determined by your doctor based on your health condition and other underlying problems. Clip 500 MG Injection is not recommended for use in children under 18 years of age. Inform your doctor if you are pregnant, planning a pregnancy or are breastfeeding before receiving Clip 500 MG Injection. Let your doctor know if you have any medical conditions like kidney, eye and heart problems before receiving this injection.

Side effects

Major & minor side effects for Clip 500 MG Injection

  • Headache
  • Running nose and cough
  • Back pain
  • Diarrhoea
  • Pale skin
  • Allergic skin reaction
  • Muscle or joint pain
  • Unusual tiredness and weakness
  • Change in color vision
  • Difficulty in breathing
  • Swelling of face, lips, eyelids, tongue, hands and feet
  • Pain in the chest region
  • Dizziness and fainting
  • Presence of blood in cough
  • Pain at the injection site

Uses of Clip 500 MG Injection

What is it prescribed for?

  • Short-term management of hemorrhage
  • Menorrhagia
  • Preventing blood loss during surgeries
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    Clip 500 MG Injection can show its action within 10-30 minutes of intravenous administration.
  • How long do the effects of this medicine last?
    The effect of Clip 500 MG Injection lasts for an average duration of 3 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Avoid consuming alcohol after receiving Clip 500 MG Injection as it may increase the risk of drowsiness and dizziness.
  • Is this a habit forming medicine?
    No habit-forming tendency has been reported for Clip 500 MG Injection
  • Can this medicine be taken during pregnancy?
    Clip 500 MG Injection is generally safe to be used in pregnancy. It is not known to cause any harm to your foetus. However, inform your doctor if you are pregnant before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    Clip 500 MG Injection is safe to be used during breastfeeding. However, inform your doctor if you are breastfeeding before taking this medicine.

Allergy

Avoid receiving Clip 500 MG Injection if you are allergic to it. Seek immediate medical attention if you notice any symptoms of allergic reactions such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.

Acquired defective color vision

Clip 500 MG Injection is not recommended for use in people with defective colour vision/colour blindness (a condition in which the individual may have difficulty in identifying different shades of colours) as this medicine has been reported to worsen this condition.

Subarachnoid hemorrhage

Subarachnoid haemorrhage is a condition in which there is bleeding into the area between the brain and its outer covering due to the rupture of a blood vessel.Clip 500 MG Injection is not recommended for use in such conditions as it may worsen your health condition and cause serious side effects.

Obstructive blood clotting disorder

Clip 500 MG Injection is not recommended for use if you have clotting disorders of the heart and blood vessels as may lead to serious side effects. The clots may also move from the place of origin and lodge in other locations.
Warnings for special population

Pregnancy

Clip 500 MG Injection is generally safe to be used in pregnancy. It is not known to cause any harm to your foetus. However, inform your doctor if you are pregnant before taking this medicine.

Breast-feeding

Clip 500 MG Injection is safe to be used during breastfeeding. However, inform your doctor if you are breastfeeding before taking this medicine.
General warnings

Use of contraceptives

Clip 500 MG Injection is not recommended for use in women using hormonal contraceptives (pills, patches, vaginal rings, or injections) as it may increase the risk of serious side effects.

Clotting disorders

Clip 500 MG Injection is not recommended for use if you have a history of clotting disorders or have an active disorder.

Eye disorders

Clip 500 MG Injection is not recommended for use if you have a condition where the blood vessels of your eye are obstructed due to clot formation.

Other medicines

Clip 500 MG Injection is known to interact with a large number of other medicines that you may be using. Report the use of all medications to your doctor before receiving this medicine.

Missed Dose

Since Clip 500 MG Injection is administered in the hospital setting by a qualified healthcare professional, the likelihood of missing a dose is very low.

Overdose

Since Clip 500 MG Injection is administered in the hospital setting by a qualified healthcare professional, the chances of an overdose are very low.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Avoid consuming alcohol after receiving Clip 500 MG Injection as it may increase the risk of drowsiness and dizziness.
Interaction with Medicine

Tamoxifen

Ethinyl Estradiol

Tretinoin

Factor IX complex

Disease interactions

Kidney diseases

Clip 500 MG Injection may increase the risk of kidney injury if you have kidney problems. Your doctor may suggest some tests to monitor your kidney function while you are on treatment with this medicine.
Food interactions
Information not available.
Lab interactions
Information not available.
Clip 500 MG Injection should be administered by a qualified healthcare professional in the clinical or hospital setting. Do not self administer it. Report any undesirable effects to the doctor promptly. You may observe a small bump at the site of injection which is normal. Inform your doctor if you have kidney, eye or heart problems. Also, let your doctor know if you are pregnant or breastfeeding. Avoid driving vehicles or drinking alcohol after receiving Clip 500 MG Injection as it may make you drowsy or sleepy.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
Clip 500 MG Injection works by stopping the formation of enzyme plasmin, which promotes the breakdown of fibrin clots to control excessive bleeding during periods, or after surgery.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Miscellaneous coagulation modifiers, Antifibrinolytic agents

Schedule

Schedule H

DailyMed - Tranexamic acid injection, solution [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 11 April 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=e8a45862-2187-49eb-892e-ade1b0cde938

Pubchem.ncbi.nlm.nih.gov. 2021. Tranexamic Acid. [online] Available at: < [Accessed 20 January 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/5526>

Medicines.org.uk. 2021. Tranexamic Acid 500Mg/5Ml Solution For Injection - Summary Of Product Characteristics (Smpc) - (Emc). [online] Available at: < [Accessed 20 January 2021].

https://www.medicines.org.uk/emc/product/3374/smpc>

Medsafe.govt.nz. 2021. [online] Available at: < [Accessed 20 January 2021].

https://www.medsafe.govt.nz/Profs/Datasheet/t/tranexamicacidMedsurgeinj.pdf>
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Information on this page was last updated on 8 Nov 2021

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