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Clindoxyl Once Daily Gel

Manufactured byGLAXOSMITHKLINEPHARMACEUTICALS LTD.
ContainsClindamycin (1 %w/w) + Benzoyl Peroxide (Topical) (5 %w/w)
Description

Clindoxyl Once Daily Gel is a combination medicine used for the treatment of inflammatory acne vulgaris. This medicine is not recommended for use in patients less than 12 years of age.

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Side effects

Major & minor side effects for Clindoxyl Once Daily Gel

  • Scaly skin
  • Skin irritation
  • Skin rash
  • Burning sensation at the application site
  • Blistering and peeling of skin
  • Itching of skin

Uses of Clindoxyl Once Daily Gel

What is it prescribed for?

  • Acne vulgaris
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before using this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before using this medicine. If the medicine is used, care should be taken such that the infant does not come into contact with the medicine. Also, the infant should be monitored closely for any undesired side effects.

Allergy

This medicine is not recommended for use in patients with a known allergy to clindamycin, any other lincosamides, benzoyl peroxide, or any other inactive ingredients present along with these medicines.

Colitis

This medicine is not recommended for use in patients with a known history of ulcerative colitis, regional enteritis, or antibiotic-associated colitis due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before using this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before using this medicine. If the medicine is used, care should be taken such that the infant does not come into contact with the medicine. Also, the infant should be monitored closely for any undesired side effects.
General warnings

Exposure to sun

Use of this medicine may cause adverse reactions of the skin on sun exposure. You are advised to take appropriate precautionary measures while stepping out into sunlight during treatment with this medicine.

Skin peeling and skin irritation

This medicine may cause skin irritation when applied, characterized by peeling of the skin. This effect is not harmful and usually subsides within 1 or 2 days after stopping the treatment.

Use on skin

This medicine is for external use only. Apply on the affected skin as recommended. Avoid contact with the eyes and mouth.

Use in children

The safety and efficacy of this medicine have not been clinically established in children less than 12 years of age.

Missed Dose

Apply the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not apply a double dose to make up for the missed one.

Overdose

An overdose of this medicine is not likely to cause severe symptoms. However, ingestion of this medicine may cause harm and immediate medical intervention may be required.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Tretinoin/ Isotretinoin

Dapsone

Neuromuscular blockers

Disease interactions

Gastrointestinal Diseases

This medicine should be used with extreme caution in patients having a history of gastrointestinal diseases, particularly colitis, due to the increased risk of worsening of the patient's condition. Report any incidence of severe diarrhea, abdominal pain, blood in stools, etc. to the doctor immediately. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.
Food interactions
Information not available.
Lab interactions
Information not available.
Apply a thin layer of the medicine to the affected area as instructed by the doctor. Follow all the usage instructions mentioned on the label or the package insert. Do not apply in larger or smaller quantities than recommended. Do not cover the application area with bandages or other coverings unless specifically instructed by the doctor.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works
Clindamycin works by stopping the growth of the bacteria that cause acne. Benzoyl peroxide works by inhibiting the growth of the bacteria and promoting the peeling of affected skin. Thus, the combination is better effective for treating acne vulgaris.
Legal Status

Approved

Approved

Unknown

Approved

Classification

Category

Topical acne agents, Lincomycin derivatives

Schedule

Schedule H

Clindamycin Topical: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2018 [cited 26 June 2018]. Available from:

https://medlineplus.gov/druginfo/meds/a609005.html

Benzoyl Peroxide Topical: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 17 May 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a601026.html

DailyMed - Clindamycin and benzoyl peroxide [Internet]. Dailymed.nlm.nih.gov. 2018 [cited 5 September 2018]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=23762e86-6b7f-4107-90df-f33705e617af

Duac Once Daily 10mg/g + 50mg/g Gel - Summary of Product Characteristics (SmPC) - (eMC) [Internet]. Medicines.org.uk. 2018 [cited 5 September 2018]. Available from:

https://www.medicines.org.uk/emc/product/6/smpc
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Information on this page was last updated on 4 Dec 2018

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.