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Clavam 150 Injection
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Clavam 150 Injection

Manufactured byALKEM LABORATORIES LTD
ContainsAmoxycillin (125 mg) + Clavulanic Acid (25 mg)
Description
Clavam 150 Injection is a combination medicine used to treat a variety of bacterial infections. Amoxycillin interferes with the growth and division process of the bacterial cell wall while clavulanic acid ensures extended anti-bacterial activity. This combination may be used to treat bacterial infections of the lungs and airways, middle ear, sinuses, skin, and the urinary tract in pediatric patients.
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Side effectsConcernsUsageRelated products

Side effects

Major & minor side effects for Clavam 150 Injection

  • Allergic Skin Reaction
  • Diarrhea
  • Fever
  • Skin yellowing
  • Easy bruising and bleeding
  • Tooth discoloration
  • Nausea or vomiting
  • Altered sense of taste
  • Convulsions
  • Swelling of face, lips, eyelids, tongue, hands and feet
  • Black or tarry stools
  • Muscle or joint pain
  • Sleeplessness
  • Irregular heartbeat

Uses of Clavam 150 Injection

What is it prescribed for?

  • Ear Infection (Otitis Media)
  • Nose Infection (Sinusitis)
  • Throat Infection (Tonsillitis/Pharyngitis)
  • Lower Respiratory Tract Infection
  • Skin Infection
  • Urinary Tract Infection
  • Bone and joint infections
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to amoxycillin, clavulanic acid, any other medicines belonging to the penicillins or cephalosporins groups, or any other inactive ingredients present in the formulation.

Liver dysfunction

This medicine is not recommended for use if you have a history of liver dysfunction associated with the use of Amoxycillin and clavulanic acid in combination.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
General warnings

Allergic Reaction

This medicine is likely to cause moderate-to-severe allergic reactions and the likelihood is very high in patients who are known to have an antibiotic allergy. Report the occurrence of any such reaction to the doctor on priority. Appropriate corrective measures and replacement with a suitable alternative may be necessary based on the clinical condition.

Diarrhea

Antibiotic therapy will cause an imbalance in the normal microbial flora of the large intestine, which may promote the growth of a bacteria called Clostridium difficile and you may experience severe diarrhea as a result. Report any such incidence to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Drug-resistance

Usage of this medicine without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of development of bacteria that are drug-resistant.

Liver disease

This medicine should be used with caution in patients with liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Form and method of administration

This medicine is generally administered either by slow intravenous injection over a period of 3-4 minutes or by intravenous infusion over a period of 30-40 minutes. It is not suitable for intramuscular administration. The patient should be shifted to oral forms as soon as possible.

Missed Dose

Since this medicine is administered by a qualified healthcare professional in the clinical or hospital setting, the likelihood of a missed dose is very low.

Overdose

Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Doxycycline

Methotrexate

Warfarin

Ethinyl Estradiol

Live cholera vaccine

Disease interactions

Mononucleosis

This medicine is not recommended for use in patients with a history of mononucleosis since it may increase the risk of skin reactions/eruptions. An alternative treatment option should be considered based on the clinical condition.

Colitis

This medicine should be used with extreme caution in patients having a history of gastrointestinal diseases, particularly colitis, since it may worsen the patient's condition. Report any incidence of severe diarrhea, abdominal pain, blood in stools, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Kidney Disease

This medicine should be used with caution in patients with a history of renal diseases or active renal diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions

Urine Sugar Test (Benedict's of Fehling's reagent)

Report the use of this medicine prior to the test. Use of this medicine may give a false-positive result for the presence of glucose/sugar in the urine. The urine sugar test should be performed with different reagents in case you are receiving this medicine.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
This medicine should be administered by a qualified healthcare professional in the clinical or hospital setting. Inform the doctor if you have a known history of allergy to this medicine. Report to the doctor all your current medicines as well as your medical conditions before receiving this medicine. Report any undesirable side effects to the doctor promptly.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works
Amoxycillin binds to certain specific receptors and prevents the formation of a necessary component for cell wall formation process. Clavulanic acid is effective against a specific species of bacteria that are resistant to other antibiotic medicines. Thus, the combination becomes effective against an extended range of bacteria.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Beta-lactamase inhibitors, Aminopenicillins

Schedule

Schedule H

[Internet]. 2017 [cited 1 August 2017]. Available from:

http://www.medsafe.govt.nz/profs/Datasheet/a/Augmentininj.pdf

[Internet]. 2017 [cited 1 August 2017]. Available from:

http://www.pharmaline.co.il/images/newsletterregistration/gsk/18032011/augmentindr.pdf

Amoxicillin and Clavulanic Acid: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 1 August 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a685024.html

Amoxicillin - DrugBank [Internet]. Drugbank.ca. 2017 [cited 16 August 2017]. Available from:

https://www.drugbank.ca/drugs/DB01060

Clavulanate - DrugBank [Internet]. Drugbank.ca. 2017 [cited 16 August 2017]. Available from:

https://www.drugbank.ca/drugs/DB00766
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Information on this page was last updated on 7 Aug 2019

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