Citicoline

Description

Citicoline is a nerve protecting agent similar to a naturally occurring substance in the body that regulates many vital processes in the brain. It is used in many brain diseases to improve the symptoms and overall quality of life. Citicoline helps to improve memory and thinking in patients with memory impairments associated with ageing. It improves brain function in patients who are recovering from a brain stroke. In persons with glaucoma (an eye disorder that lead to vision loss), citicoline cause improvements in vision. Citicoline influences cognitive abilities and improves nerve transmission. It is also believed to repair damaged nerve cells in the brain. Side effects of citicoline are headache, irregular heartbeats, sleeplessness, low blood pressure and diarrhoea. Citicoline is available as an oral form to be taken by mouth and as an injection to be administered into the vein or muscle. You can take Citicoline oral forms with or without food. Injectable forms are administered by a qualified/trained healthcare professional in the clinic or hospital.

Side effects

Major & minor side effects for Citicoline

  • Headache
  • Dizziness
  • Shaking of hands or feet
  • Sleeplessness
  • Irregular heartbeat
  • Low blood pressure
  • Diarrhoea
  • Nausea
  • Stomach pain
  • Injection site pain
  • Blurred vision

Uses of Citicoline

What is it prescribed for?

  • Acute ischemic stroke
  • Alzheimer's disease
  • Cerebral insufficiency
  • Other diseases of the brain
  • Glaucoma
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Concerns

Commonly asked questions

  • Onset of action
    The onset of action for Citicoline is not clinically determined. You may have to use this medicine for the long-term to get complete benefits.
  • Duration of effect
    The duration of action for Citicoline is not clinically determined.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendency has been reported for Citicoline.
  • Usage in pregnancy?
    The safety and efficacy of Citicoline treatment for pregnant women are not clinically established. Hence do not use this medicine unless directed by your doctor.
  • Usage while breast-feeding?
    The safety and efficacy of Citicoline treatment for lactating/breastfeeding women are not clinically established. Hence do not use this medicine unless directed by your doctor.

Allergy

Avoid taking Citicoline if you are previously allergic to it. Serious allergic reactions to this medicine are rare. Seek immediate medical attention if you notice any symptoms of allergic reactions such as skin rash, breathing difficulties, swelling of the face/tongue/throat, etc.

Hypertonia

Hypertonia is a condition of too much muscle tone in the body. This condition makes it difficult to flex and move around normally. It occurs when the brain and spinal cord are affected by injury or illness before, during, or after birth. Citicoline is not recommended to use in patients with this condition.
Warnings for special population

Pregnancy

The safety and efficacy of Citicoline treatment for pregnant women are not clinically established. Hence do not use this medicine unless directed by your doctor.

Breast-feeding

The safety and efficacy of Citicoline treatment for lactating/breastfeeding women are not clinically established. Hence do not use this medicine unless directed by your doctor.
General warnings

Drowsiness

In some cases, Citicoline therapy may cause drowsiness and hence the patient should refrain from driving or performing tasks that require a high level of mental alertness.

Mental illness

Citicoline should be used with caution in patients with mental illness such as depression, schizophrenia, anxiety disorders, eating disorders and addictive behaviours.

Missed Dose

Oral forms: Try not to skip a dose of citicoline. And if a dose is skipped, do not add it up to the next dose. Injection: Since citicoline is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of missing a dose is very low.

Overdose

Oral forms: Seek emergency medical treatment or contact the doctor in case of an overdose. Injection: Since citicoline is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Levodopa

Meclofenoxate

Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
Oral form: Take citicoline as instructed by the doctor. Do not take this medicine in smaller or larger quantities than recommended. This medicine can be taken with or after food. Drink an adequate amount of water. Injection: Citicoline should be administered by a qualified healthcare professional in the clinical or hospital setting. Report any undesirable side effects to the doctor promptly.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Effect on sleep is not established

How it works
Citicoline works by replenishing some necessary chemicals in the brain such as phosphatidylcholine methionine, betaine, cytidine, etc. These brain chemicals improve brain function by regulating the process of cognition and awareness. It also plays a vital role in neural communication by raising the levels of substances that send messages in the brain.
Legal Status

Approved

Unknown

Approved

Unknown

Classification

Category

Nootropics, Neurotrophics

Schedule

Schedule H

Drsertus.com. 2021. [online] Available at: < [Accessed 12 February 2021].

http://www.drsertus.com/wp-content/uploads/SERTOZIN-EN.pdf>

Frank, K., Patel, K., Lopez, G. and Willis, B., 2021. CDP-choline Research Analysis. [online] Examine.com. Available at: < [Accessed 12 February 2021].

https://examine.com/supplements/cdp-choline/>

Go.drugbank.com. 2021. Citicoline | DrugBank Online. [online] Available at: < [Accessed 15 March 2021].

https://go.drugbank.com/drugs/DB12153>

Pubchem.ncbi.nlm.nih.gov. 2021. Citicoline. [online] Available at: < [Accessed 15 March 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Citicoline>

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Information on this page was last updated on 15 Mar 2021

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.