Cisapride

Description

Cisapride is an effective medicine, used to increase the mobility of food in the stomach and intestine. It is used for the treatment of diseases like Non-ulcer dyspepsia, Gastro-intestinal reflux disease etc. The cardiovascular side effects of this medicine are very prominent and hence caution is advised while using it.

Side effects

Major & minor side effects for Cisapride

  • Heart rhythm disorders
  • Difficulty in breathing
  • Headache
  • Nausea or vomiting
  • Urinary tract infection
  • Upper respiratory tract infection
  • Joint pain
  • Blurred vision
  • Sleeplessnes

Uses of Cisapride

What is it prescribed for?

  • Non-ulcer dyspepsia
  • Gastroparesis
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Concerns

Commonly asked questions

  • Onset of action
    The effect of this medicine can be observed within 30-60 minutes of administration.
  • Duration of effect
    The effect of this medicine lasts for an average duration of 7-10 hours.
  • Safe with alcohol?
    Reduce or minimize the uptake of alcohol while taking this medicine. Contact your doctor if any unwanted effects are observed.
  • Is it habit forming?
    No habit forming tendencies were reported.
  • Usage in pregnancy?
    Use of this medicine in pregnant women is not recommended unless absolutely necessary. It should be used only if the potential benefits outweigh the associated risks. Consult your doctor before taking this medicine.
  • Usage while breast-feeding?
    Use of this medicine in breastfeeding mothers is not recommended. Breastfeeding should be discontinued if it is absolutely necesarry to take this medicine. Consult your doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known history of allergy to Cisapride or any other ingredient present along with it.

Gastrointestinal haemorrhage

This medicine is not recommended for use in patients having internal bleeding of the stomach and intestine. This may be attributed to various reasons including a ruptured bowel (Gastrointestinal Perforation).

Mechanical bowel obstruction

This medicine is not recommended for use in patients having a blockage in the intestine.
Warnings for special population

Pregnancy

Use of this medicine in pregnant women is not recommended unless absolutely necessary. It should be used only if the potential benefits outweigh the associated risks. Consult your doctor before taking this medicine.

Breast-feeding

Use of this medicine in breastfeeding mothers is not recommended. Breastfeeding should be discontinued if it is absolutely necesarry to take this medicine. Consult your doctor before taking this medicine.
General warnings

Geriatric use

This medicine should be used with caution in elderly as the risk of severe adverse effects is very high.

Bleeding of stomach and intestine

Report any instance indicating bleeding of the stomach like presence of blood in stools, black or coffee colored stools to the doctor. This medicine should not be used if bleeding is evident or even suspected.

Mechanical obstruction of stomach

Report any incidence indicating intestinal blockage like severe bloating, nausea, vomiting, severe abdominal cramps, constipation etc to the doctor. Use of this medicine is not recommended in such cases.

Other medicine

This medicine is reported to interact with a large number of medicines that you might be using. Report the use of all medicine including supplements and herbs to the doctor. Do not start or stop the use of any medicine without consulting your doctor.

Cardiovascular effects

This medicine is reported to have caused severe side effects on the heart and blood vessels. Extreme caution is advised while using this medicine as these side effects can be fatal. Special attention is required if you have a pre-existing heart condition.

Kidney impairment

This medicine should be used with caution if you have a kidney disease or the normal function is impaired.

Missed Dose

Take the missed dose as soon as you remember. The missed dose can be skipped if it is almost time for the next scheduled dose.

Overdose

Consult a doctor if an overdose is suspected. You may require medical intervention if the symptoms are severe. Symptoms may include nausea, vomiting, nervousness, headache, borborygmi etc.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Use of alcohol while taking this medicine increases the risk of adverse of effects significantly.

Instructions

Reduce or minimize the uptake of alcohol while taking this medicine. Contact your doctor if any unwanted effects are observed.
Interaction with Medicine

Amitriptyline

Clarithromycin

Fluconazole

Cimetidine

Cyclosporin A

Disease interactions

Disease

Information not available.
Food interactions
It is advised to not consume grapefruit juice in large quantities while taking this medicine as the likelihood of unwanted effects increase. Consult your doctor if an undesirable effect is experienced.
Lab interactions
Information not available.
Take Cisapride as instructed by the doctor. This medicine should be taken at least 15-30 minutes before food.
Miscelleneous

To be taken before food

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine acts by increasing the concentration of a certain chemical at the nerve endings causing an increase in stomach muscle movement. This helps in the faster movement of food from the stomach to the intestine.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Gastrointestinal agents

Schedule

Schedule H

Cisapride | C23H29ClFN3O4 - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2017 [cited 26 March 2017]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/2769#section=Top

Cisapride - DrugBank [Internet]. Drugbank.ca. 2017 [cited 16 November 2017]. Available from:

https://www.drugbank.ca/drugs/DB00604

Cisapride: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 16 November 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a694006.html

Prescribing medicines in pregnancy database [Internet]. Therapeutic Goods Administration (TGA). 2017 [cited 16 November 2017]. Available from:

http://www.tga.gov.au/prescribing-medicines-pregnancy-database

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Information on this page was last updated on 16 Nov 2017

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.