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Ciprogyl 500/300 Tablet

Manufactured byMANKIND PHARMACEUTICALS LTD
ContainsCiprofloxacin (500 mg) + Tinidazole (300 mg)
Description
Ciprogyl 500/300 Tablet is a combination of Ciprofloxacin and Tinidazole. It is used to treat a variety of infections affecting various parts of your body like the lungs, genitals and urinary tract. This infection is usually caused by different microorganisms like bacteria and protozoa. It works by stopping the growth of microorganisms causing the infection. Ciprogyl 500/300 Tablet can cause side effects like diarrhoea, stomach pain, headache, weakness, change in taste, nausea, and vomiting. Consult your doctor if these side effects persist for a long time or get worsen. Avoid activities that require mental focus like driving and operating machines, as this medicine may cause dizziness. Ciprogyl 500/300 Tablet is usually taken one hour before or two hours after meals or as prescribed by your doctor. Take this medicine around the same time every day for the ease of remembering. Complete the whole treatment to feel better. Ciprogyl 500/300 Tablet is not prescribed if you are allergic to it or have any skeletal condition like tendonitis (swelling of fibres that attach bone with muscles) or myasthenia gravis (severe weakness of the muscles). This medicine can make birth control pills less effective. You may be asked to take different way of birth control methods to prevent unintended pregnancy. Ciprogyl 500/300 Tablet is not recommended to be used in children and adolescents below 18 years of age. Inform your doctor if you have any liver or kidney problems. Your dose can be adjusted in such cases. Report all your current medications as they can interact with Ciprogyl 500/300 Tablet and may cause side effects. If you are pregnant or breastfeeding, consult your doctor first before taking this medicine.

Side effects

Major & minor side effects for Ciprogyl 500/300 Tablet

  • Diarrhoea
  • Constipation
  • Runny Nose
  • Sneezing
  • Change in taste
  • Dizziness
  • Headache
  • Nausea and Vomiting

Uses of Ciprogyl 500/300 Tablet

What is it prescribed for?

  • Community acquired pneumonia
  • Bronchitis
  • Pyelonephriits
  • Cystitis
  • Gonorrhea
  • Joint infection
  • Amoebiasis
  • Bacterial vaginitis
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The time taken for Ciprogyl 500/300 Tablet to show its effect is not known.
  • How long do the effects of this medicine last?
    The effect of Ciprogyl 500/300 Tablet lasts for an average of 24 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol with Ciprogyl 500/300 Tablet may lower your blood pressure and can cause dizziness, headache, etc.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Ciprogyl 500/300 Tablet.
  • Can this medicine be taken during pregnancy?
    Ciprogyl 500/300 Tablet should be avoided during pregnancy due to the risk of adverse effects on your developing baby. Take this medicine only upon your doctor's recommendation.
  • Can this medicine be taken while breast-feeding?
    Ciprogyl 500/300 Tablet passes into breast milk. Therefore, it is not recommended to be taken while breastfeeding. Consult your doctor for understanding all risks and benefits associated with this medicine before taking it.

Allergy

Ciprogyl 500/300 Tablet is not recommended for use if you are allergic to it. Taking this medicine in such cases could lead to redness, swelling (anywhere in your body), hives (itchy, painful eruptions that sting) and breathing difficulty etc.

Tendinitis or tendon rupture

Ciprogyl 500/300 Tablet can cause muscle damage especially in old age. Do not take Ciprogyl 500/300 Tablet if you have tendonitis (swelling of fibres that attach bone with muscles) or tendon rupture (a partial or complete tear of the tendon- the tissue that connects muscle to bone).

Myasthenia gravis

Myasthenia gravis is a skeletal muscle condition characterized by severe weakness of any of the muscles under your voluntary control, including the arms and legs. Ciprogyl 500/300 Tablet should be avoided if you have myasthenia gravis since it may worsen your condition.
Warnings for special population

Pregnancy

Ciprogyl 500/300 Tablet should be avoided during pregnancy due to the risk of adverse effects on your developing baby. Take this medicine only upon your doctor's recommendation.

Breast-feeding

Ciprogyl 500/300 Tablet passes into breast milk. Therefore, it is not recommended to be taken while breastfeeding. Consult your doctor for understanding all risks and benefits associated with this medicine before taking it.
General warnings

Antibiotic resistance

Complete the entire course of treatment with Ciprogyl 500/300 Tablet, even if your condition gets better to avoid antibiotic resistance (the bacteria may become resistant to antibiotics). If you still feel unwell after completing your antibiotic course, consult your doctor.

Blood cell count

If you have a low blood cell count, prolong therapy with Ciprogyl 500/300 Tablet may further decrease your cell count. An alternative medicine may be prescribed by your physician.

Neurotoxicity

Neurotoxicity occurs when exposure to certain toxic substances (neurotoxicants) alters the normal activity of your nervous system and show effects like convulsions, peripheral neuropathy (weakness, numbness and pain from nerve damage, usually in the hands and feet), headache, and dizziness. Ciprogyl 500/300 Tablet rarely cause neurotoxicity.

Impaired liver function

Ciprogyl 500/300 Tablet should be taken with caution if you have liver problems as this medicine is broken down in the liver. An Impaired liver will not use the medicine properly, leading to increased levels of unused medicine in your blood. Frequent monitoring of liver functions and/or dose adjustments may be necessary based on your condition.

Driving or Operating machines

Ciprogyl 500/300 Tablet may cause sleepiness or dizziness in some people. Therefore, avoid driving vehicles and operating heavy machines after taking this medicine.

Use in Children

Ciprogyl 500/300 Tablet is not recommended for use in children and adolescents below 18 years of age since the safety and efficacy of use are not clinically established.

Missed Dose

Try not to skip a dose of Ciprogyl 500/300 Tablet. And if a dose is skipped, do not add it up to the next dose.

Overdose

Seek emergency medical treatment or contact your doctor in case of an overdose of Ciprogyl 500/300 Tablet.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol with Ciprogyl 500/300 Tablet may lower your blood pressure and can cause dizziness, headache, etc.
Interaction with Medicine

Escitalopram

Ethinyl Estradiol

Warfarin

Cholera Vaccine (live)

Atorvastatin

Disease interactions

Central nervous system disorders

Ciprogyl 500/300 Tablet should be used cautiously if you have nerve problems, seizures, depression, and psychotic reactions as it can trigger these conditions. Inform your doctor immediately if these reactions occur.

Colitis

Ciprogyl 500/300 Tablet should be used with extreme caution if you have gastrointestinal (stomach and intestines) problems, particularly colitis (swelling of the inner lining of the colon), as it may worsen your condition.

QT Prolongation

Ciprogyl 500/300 Tablet may cause a heart rhythm problem called prolonged QT intervals (an electrical heartbeat disturbance) in some people who are taking heart medications. It may result in fast, rapid, and irregular heartbeats.

Kidney Disease

Ciprogyl 500/300 Tablet should be taken with caution if you have a kidney problem as a damaged kidney may lead to accumulation of unused medicine in your body, increasing the risk of side effects. Your doctor may suggest another suitable medicine or adjust the dose based on your condition.
Food interactions
Ciprogyl 500/300 Tablet will not show the desired effects if consumed with dairy products. A gap of at least two hours should be maintained between this tablet and dairy products.
Lab interactions
Information not available.
Take Ciprogyl 500/300 Tablet as instructed by the doctor. Do not break, crush or chew the tablet. Ciprogyl 500/300 Tablet is given for a short period.Hence, it is important to complete the whole treatment for maximum benefits. Avoid consuming dairy products and drinking alcohol while taking Ciprogyl 500/300 Tablet as it reduces the efficiency of this medicine.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Ciprogyl 500/300 Tablet is composed of Ciprofloxacin and Tinidazole. Ciprofloxacin stops the action of a bacterial enzyme called DNA-gyrase. This helps to kill or prevent the growth of bacteria in the body. Tinidazole works by inhibiting the growth of bacteria and protozoa by interfering with its DNA synthesis.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Quinolones, Anthelmintics

Schedule

Schedule H

Pubchem.ncbi.nlm.nih.gov. 2021. Tinidazole. [online] Available at: [Accessed 31 May 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Tinidazole

Pubchem.ncbi.nlm.nih.gov. 2020. Ciprofloxacin. [online] Available at: [Accessed 23 December 2020].

https://pubchem.ncbi.nlm.nih.gov/compound/Ciprofloxacin

Medicines.org.uk. 2021. Ciprofloxacin 500mg film-coated tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: [Accessed 14 September 2021].

https://www.medicines.org.uk/emc/product/7257/smpc

Medicines.org.uk. 2021. Fasigyn 500mg film-coated tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: [Accessed 14 September 2021].

https://www.medicines.org.uk/emc/product/1066
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Information on this page was last updated on 27 Mar 2023

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