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Ciledge CT 6.25 Tablet
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Ciledge CT 6.25 Tablet

Manufactured byCADILA PHARMACEUTICALS LTD
ContainsCilnidipine (10 mg) + Chlorthalidone (6.25 mg)
Description
Ciledge CT 6.25 Tablet is a combination of Cilnidipine and Chlorthalidone. It is used in the treatment of Uncontrolled Hypertension (high blood pressure). This medicine decreases your heart rate and relaxes the blood vessels so that blood can flow more easily throughout your body, thus controls your blood pressure. Ciledge CT 6.25 Tablet can cause side effects like stomach pain, swelling in your hands and feet, irregular heartbeats, headache, etc. Consult your doctor if these side effect persists or worsen. This medicine can cause dizziness, therefore avoid activities that require mental focus like driving or operating machines. Ciledge CT 6.25 Tablet should be taken with food preferably in the morning to avoid frequent urination at night. This medicine contains a diuretic (water pill) and will increase your urination frequency, hence avoid taking it within four hours before going to bed. Do not stop taking this medicine before consulting your doctor. Your blood pressure may seem to be in control but abrupt discontinuation of this medicine may lead to a high risk of heart attack and stroke (decreased blood flow to your brain). Ciledge CT 6.25 Tablet is not recommended if you are allergic to it. Inform your doctor if you have any heart, liver or kidney problems. Inform your doctor if you are taking any other medicines or supplements as they may interact with each other and increase the risk of side effects. Ciledge CT 6.25 Tablet is not recommended in children below 18 years, if you are pregnant, or are breastfeeding unless prescribed by your doctor.
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Side effectsConcernsUsageRelated products

Side effects

Major & minor side effects for Ciledge CT 6.25 Tablet

  • Low blood pressure
  • Dizziness
  • Fast heartbeat
  • Muscle pain
  • Shaking of hands or feet
  • Skin rash
  • Decreased sexual urge
  • Increased urination frequency
  • Stomach pain
  • Photosensitivity
  • Constipation
  • Diarrhoea
  • Loss of appetite
  • Nausea
  • Vomiting
  • Headache
  • Blurred vision
  • Restlessness

Uses of Ciledge CT 6.25 Tablet

What is it prescribed for?

  • Hypertension
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for Ciledge CT 6.25 Tablet to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which Ciledge CT 6.25 Tablet remains active in your body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment of Ciledge CT 6.25 Tablet as it may cause a further decrease in your blood pressure. You may experience symptoms such as dizziness, fainting, change in heart rate, etc. Avoid performing activities such as driving or operating machines
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Ciledge CT 6.25 Tablet.
  • Can this medicine be taken during pregnancy?
    Ciledge CT 6.25 Tablet is not recommended in pregnancy as it can cause serious complications to your foetus. If you are on this medication, consult your doctor before you plan your pregnancy.
  • Can this medicine be taken while breast-feeding?
    Ciledge CT 6.25 Tablet is not recommended for use in breastfeeding as it can pass through breastmilk and lead to low blood pressure symptoms in your baby.

Allergy

Ciledge CT 6.25 Tablet is not recommended for use if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, swelling and/or itching (especially in the face, lips, throat, etc.), dizziness, breathing difficulty, etc.

Heart diseases

Ciledge CT 6.25 Tablet is not recommended for use if you have any heart problems. This includes heart attack (a condition that occurs when blood flow to the heart is interrupted by a blockage or blood clot), rhythm disorders (abnormal heartbeats), angina (chest pain), etc. This medicine weakens the contractions of your heart and reduces your blood pressure. Using it while you have heart problems will worsen your condition.

Anuria

Anuria is a condition where the kidney is unable to form urine. This medicine acts by removing excess water and sodium from your body. Using this medicine if you have pre-existing kidney problems will lead to its accumulation and further damage to your kidney. Hence, Ciledge CT 6.25 Tablet is not recommended for use if you have kidney troubles.

Severe liver impairment

Ciledge CT 6.25 Tablet is not recommended if you have severe liver problems. This medicine may accumulate in the liver and further lead to liver damage and increased risk of side effects.
Warnings for special population

Pregnancy

Ciledge CT 6.25 Tablet is not recommended in pregnancy as it can cause serious complications to your foetus. If you are on this medication, consult your doctor before you plan your pregnancy.

Breast-feeding

Ciledge CT 6.25 Tablet is not recommended for use in breastfeeding as it can pass through breastmilk and lead to low blood pressure symptoms in your baby.
General warnings

Use in Children

Ciledge CT 6.25 Tablet is not recommended for use in children below 18 years of age since the safety and efficacy of use are not clinically established.

Volume and electrolyte disturbances

Ciledge CT 6.25 Tablet may alter your blood volume and electrolyte levels. This may cause dizziness, dry mouth, irregular heartbeat and acid-base imbalance (an imbalance between carbon dioxide (acid) and bicarbonates (base) in your blood). This risk is especially higher if you have kidney and liver troubles. Your blood pressure and electrolyte levels have to be closely monitored while you are taking this medicine.

Driving or operating machines

Ciledge CT 6.25 Tablet may cause symptoms such as drowsiness, blurred vision, or dizziness in some people. It is advised that you do not perform any activities that require high mental alertness like driving vehicles or operating heavy machines during treatment with this medicine if you experience any of these symptoms.

Hyperkalemia

Hyperkalemia is an increase in potassium levels in your blood. Ciledge CT 6.25 Tablet may increase the potassium levels in your blood. This may cause serious side effects such as cardiac rhythm irregularities(changes in the heartbeat). It is advised that you avoid potassium-rich foods (potatoes, bananas) and other medicines that may increase your potassium levels (ACE inhibitors and potassium supplements) during treatment with this medicine.

Missed Dose

If you forget to take the dose of Ciledge CT 6.25 Tablet at a given time, then take it as soon as you remember. If it is time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Never take more than the dose prescribed by your doctor. If you have intentionally or accidentally consumed more than the prescribed amount of Ciledge CT 6.25 Tablet, contact your doctor immediately for further guidance.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment of Ciledge CT 6.25 Tablet as it may cause a further decrease in your blood pressure. You may experience symptoms such as dizziness, fainting, change in heart rate, etc. Avoid performing activities such as driving or operating machines
Interaction with Medicine

Carbamazepine

Cisapride

Lithium

Amiodarone

Insulin

Cimetidine

Disease interactions

Hypotension

Hypotension is a decrease in your blood pressure. Taking Ciledge CT 6.25 Tablet will further reduce your blood pressure which can be fatal, especially if you have low levels of sodium in your body or if you have low fluid volumes due to excessive vomiting, diarrhoea, burns, kidney failure, etc.

Congestive heart failure

Heart failure occurs when your heart muscle is not able to pump blood normally. Ciledge CT 6.25 Tablet should be used with caution if you have conditions such as heart failure because this medicine may worsen your condition. Your doctor will closely monitor the functioning of your heart while you take this medicine.

Diabetes

Ciledge CT 6.25 Tablet can alter your blood glucose levels. If you are diabetic, use this medicine with caution. Monitor your blood glucose levels regularly.

Hyperuricemia

Hyperuricemia is an increased level of uric acid in the blood. Ciledge CT 6.25 Tablet should be used with caution if you have chronic kidney failure due to the increased risk of hyperuricemia. Your doctor will suggest tests to monitor your blood uric acid levels as well as your kidney functions.

Hyperlipidemia

Hyperlipidemia is the increased levels of cholesterols and triglycerides in the blood. Ciledge CT 6.25 Tablet should be used with caution if you have hyperlipidemia since it may increase your cholesterol and triglyceride levels. Your doctor will suggest tests to monitor your cholesterol and triglyceride levels.
Food interactions
Consumption of grapefruit juice is not recommended during treatment with Ciledge CT 6.25 Tablet as grapefruit juice can increase the absorption of this medicine in your blood. This could lead to excessive lowering of blood pressure or worsen side effects.
Lab interactions

Urinary vanillylmandelic acid

Urinary vanillylmandelic acid test is performed to determine the presence of certain tumours. Inform your doctor or the lab technician about the use of Ciledge CT 6.25 Tablet as this medicine is likely to give a false-positive result.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Ciledge CT 6.25 Tablet exactly as advised by your doctor. Do not take in larger amounts than prescribed. Drink an adequate amount of water. Monitoring of kidney function and electrolytes levels is necessary while taking this medicine. Report any serious side effects to your doctor on priority. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Chlorthalidone works by increasing the excretion of water and sodium from your kidneys. This helps in bringing down the blood pressure as well as swelling. Cilnidipine acts by blocking the inflow of calcium (responsible for the contraction of blood vessels) and causes relaxation, thereby promoting the smooth flow of blood. Thus, this combination medicine is better effective in treating high blood pressure.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Thiazide diuretics, Calcium channel blocking agents

Schedule

Schedule H

Lloydhealthcare.org. 2021. Lloyd Healthcare - CILIDIN O. [online] Available at: [Accessed 24 November 2021].

https://www.lloydhealthcare.org/cilidin-o.php

Pubchem.ncbi.nlm.nih.gov. 2021. Cilnidipine. [online] Available at: [Accessed 31 August 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/cilnidipine#section=Top

Dailymed.nlm.nih.gov. 2021. DailyMed - CHLORTHALIDONE- chlorthalidone tablet. [online] Available at: [Accessed 30 July 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=36ef8d83-45f2-4873-b7cb-1be096d14d18

Stewart, M., 2021. Chlortalidone side effects & other chlortalidone info - Patient. [online] Patient.info. Available at: o/medicine/chlortalidone-tablets [Accessed 30 July 2021].

https://patient.inf
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Information on this page was last updated on 24 Mar 2023

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