Cetilistat

Description

Cetilistat is used for the treatment of obesity, particularly in patients with type II diabetes mellitus and dyslipidemia. It is used in patients with a body mass index (BMI) higher than 25 kg/meter squared even with dietary regulations and an appropriate amount of exercise. This medicine should be taken along with a healthy low-fat diet and an abundant amount of exercise to achieve the best possible results.

Side effects

Major & minor side effects for Cetilistat

  • Headache
  • Nausea or vomiting
  • Unusual tiredness or weakness
  • Tooth problems
  • Trouble with sleeping
  • Itching and skin rash
  • Yellow colored eyes or skin
  • Abdominal pain and discomfort
  • Abnormal bowel movements
  • Difficulty in breathing
  • Dark colored urine
  • Loss of appetite

Uses of Cetilistat

What is it prescribed for?

  • Obesity
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time taken by this medicine to show its effect is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains effective in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women.

Allergy

This medicine is not recommended for use in patients with a known allergy to cetilistat or any other inactive ingredients present in the formulation.

Chronic malabsorption syndrome

This medicine is not recommended for use in patients diagnosed with a chronic malabsorption syndrome, a condition where the body is not able to absorb nutrients from the dietary intake.

Cholestasis

This medicine is not recommended for use in patients suffering from cholestasis, a condition where the flow of bile from the liver is impaired.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women.

Breast-feeding

This medicine is not recommended for use in breastfeeding women.
General warnings

Other medicines

This medicine may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you report all your current medicines, including any herbs and supplements, to the doctor before beginning treatment with this medicine.

Use in elderly

This medicine should be used with caution in the elderly patients since the risk of adverse effects is significantly higher. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the patient's clinical condition.

Use in children

This medicine is not recommended for use in children since the safety and efficacy of use are not clinically established.

Kidney diseases

This medicine should be used with caution in patients with a history of kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function tests, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Liver diseases

This medicine should be used with caution in patients with a history of liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function tests, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Gastrointestinal effects

This medicine may increase gastrointestinal adverse effects such as diarrhea, bloating, loss of appetite, flatulence, etc. in some patients. This risk is especially higher if the patient consumes a meal with a high amount of fat. Your doctor/dietitian will suggest an appropriate diet for you based on your clinical condition.

Organ transplant

This medicine is not recommended for use in patients who have had an organ transplant procedure performed in the recent times due to an increase in the risk of rejection.

Missed Dose

Take the missed dose as soon as you remember unless 1 hour has passed after your meal. Skip the missed dose If it is almost time for your next dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Enoxaparin

Insulin

Levothyroxine

Dapagliflozin

Glimepiride

Amiodarone

Apixaban

Cyclosporine

Warfarin

Metformin

Disease interactions

Malabsorption

This medicine is not recommended for use in patients suffering from chronic malabsorption syndrome or cholestasis since it may worsen the patient's condition. Replacement with a suitable alternative should be considered based on the patient's clinical condition.

Diabetes

This medicine should be used with caution in patients suffering from diabetes due to the increased risk of altered blood glucose levels. Close monitoring of blood glucose levels is recommended for these patients. Appropriate dose adjustments, either in this medicine or in the antidiabetic medicines, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine exactly as prescribed by the doctor. Your doctor/dietitian will suggest an appropriate exercise and diet regimen, including any supplements, along with this medicine to achieve the best possible results. Follow all the instructions given by your doctor/dietitian. Ensure that the course of treatment is completed. Do not stop the use of any medicine without consulting your doctor.
Miscelleneous

To be taken after food

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine blocks the digestion and absorption of fats; this leads to reduced energy intake and weight loss.
Legal Status

Unknown

Unknown

Approved

Unknown

Classification

Category

Peripherally acting antiobesity agents

Schedule

Schedule H

[Internet]. Pmda.go.jp. 2018 [cited 18 September 2018]. Available from:

https://www.pmda.go.jp/files/000153463.pdf

Cetilistat [Internet]. Pubchem.ncbi.nlm.nih.gov. 2018 [cited 18 September 2018]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/Cetilistat#section=2D-Structure

Cetilistat - DrugBank [Internet]. Drugbank.ca. 2018 [cited 18 September 2018]. Available from:

https://www.drugbank.ca/drugs/DB06586

J G. Cetilistat for the treatment of obesity. - PubMed - NCBI [Internet]. Ncbi.nlm.nih.gov. 2018 [cited 18 September 2018]. Available from:

https://www.ncbi.nlm.nih.gov/pubmed/24524093

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Information on this page was last updated on 19 Sep 2018

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.