Cerivastatin

Description

Cerivastatin is used to reduce the level of bad cholesterol in the body. It increases the levels of high-density lipoproteins (HDL) which reduce the risk of heart attacks, atherosclerosis, angina. A proper diet and regular exercise should be maintained along with taking this medicine.

Side effects

Major & minor side effects for Cerivastatin

  • Nausea or Vomiting
  • Dry mouth
  • Chest pain
  • Cough
  • Nasal congestion
  • Diarrhea
  • Sore throat
  • Rash
  • Depression

Uses of Cerivastatin

What is it prescribed for?

  • Primary Hypercholesterolemia type-IIa, IIb
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No-habit forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women.

Active liver disease

This medicine is not recommended for use in patients with active liver diseases or any abnormality in the liver function tests due to the increased risk of worsening of the patient's condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to Cerivastatin or any other inactive ingredients present along with it.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women.

Breast-feeding

This medicine is not recommended for use in breastfeeding women.
General warnings

Myopathy and Rhabdomyolysis

This medicine may cause muscle breakdown and rhabdomyolysis in some patients, a condition which can be fatal. This risk is especially higher in the elderly population and in patients with active muscle disorders. Report any unusual symptoms to the doctor immediately. Replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Liver Disease

This medicine should be used with extreme caution in patients with a history of liver diseases due to the increased risk of severe adverse effects. Regular monitoring of liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Other medicines

Cerivastatin may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Use in Children

This medicine is not recommended for use in patients below 18 years of age since the safety and efficacy of use are not clinically established.

Kidney Disease

This medicine should be used with caution in patients with kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function is necessary for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Alcohol consumption

Cerivastatin should be used with caution in patients who consume large quantities of alcohol and/or have a history of chronic liver disease due to the increased risk of severe adverse effects.

Missed Dose

Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Leflunomide

Atazanavir

Cyclosporine

Gemfibrozil

Colchicine

Disease interactions

Liver Disease

This medicine should be used with extreme caution in patients with a history of liver diseases due to the increased risk of severe adverse effects. Regular monitoring of liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition. It is recommended to discontinue the medicine if the liver function is abnormal even after reducing the dosage.

Rhabdomyolysis

This medicine should be used with extreme caution in patients with rhabdomyolysis due to the increased risk of severe adverse effects and worsening of the condition. Report any unusual symptoms to the doctor on priority. An alternative treatment option should be considered in some cases based on the clinical condition.

Kidney Disease

This medicine should be used with caution in patients with kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function is necessary for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Consumption of grapefruit juice is not recommended during treatment with this medicine due to the increased risk of side effects such as liver damage and rare but serious conditions called rhabdomyolysis. Report any symptoms such as fatigue, weakness, yellowing of the skin or eyes, fever, joint pain, etc. to the doctor immediately.
Lab interactions
Information not available.
Take this medicine with or without food. Do not take in larger amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Does not cause sleepiness

How it works
This medicine reduces the production of cholesterol from the liver. This ultimately helps in reducing the levels of cholesterol in the blood and the risk of complications related to high levels of cholesterol in the blood.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Statins

Schedule

Schedule H

[Internet]. Accessdata.fda.gov. 2019 [cited 3 January 2019]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2001/20740S18lbl.pdf

Cerivastatin [Internet]. Pubchem.ncbi.nlm.nih.gov. 2019 [cited 3 January 2019]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/cerivastatin

Cerivastatin - DrugBank [Internet]. Drugbank.ca. 2019 [cited 3 January 2019]. Available from:

https://www.drugbank.ca/drugs/DB00439

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Information on this page was last updated on 20 Feb 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.