Ceftizoxime

Description

Ceftizoxime is a broad-spectrum antibiotic used to treat a variety of bacterial infections including urinary tract infections, pelvic inflammatory disease, gonorrhea, skin and skin structure infections, bone and joint infections, intraabdominal infections, etc. This medicine is not recommended for use in case of a common cold, flu, or other viral infections since it is active against infections caused by certain bacterial species only.

Side effects

Major & minor side effects for Ceftizoxime

  • Fever
  • Itching of skin
  • Skin rash
  • Diarrhea
  • Nausea or Vomiting
  • Numbness
  • Pain at the injection site
  • Chest pain
  • Chills
  • Cough

Uses of Ceftizoxime

What is it prescribed for?

  • Urinary Tract Infection
  • Pelvic Inflammatory Disease
  • Gonococcal Urethritis and Cervicitis
  • Bacterial infections
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time required for this medicine to remain active in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
  • Usage while breast-feeding?
    This medicine is recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to ceftizoxime, any other beta-lactam antibiotics, or any other inactive ingredients present along with it.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Breast-feeding

This medicine is recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
General warnings

Clostridium difficile-associated Diarrhea

Antibiotic therapy will cause an imbalance in the normal microbial flora of the large intestine, which may promote the growth of a bacteria called Clostridium difficile and you may experience severe diarrhea as a result. Report any such incidence to the doctor on priority and avoid usage of this medicine in such cases.

Kidney impairment

This medicine should be used with extreme caution in patients suffering from kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Drug resistance

Usage of this medicine without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of development of bacteria that are drug resistant.

Use in children

This medicine is not recommended for use in patients less than 6 months of age since the safety and efficacy of use are not clinically established.

Sodium

This medicine contains sodium in it and therefore it should be used with caution in patients with conditions that may require sodium restriction, such as congestive heart failure, hypertension (high blood pressure), and fluid retention.

Missed Dose

Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of a missed dose is very less.

Overdose

Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Live cholera vaccine

Furosemide

Probenecid

Chloramphenicol

Gentamicin

Ethinyl Estradiol

Warfarin

Disease interactions

Renal Dysfunction

This medicine should be used with caution in patients suffering from kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Colitis

This medicine should be used with extreme caution in patients having a history of gastrointestinal diseases, particularly colitis, since it may worsen the patient's condition. Report any incidence of severe diarrhea, abdominal pain, blood in stools, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Liver Disease

This medicine should be used with caution in patients suffering from liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Seizure disorders

This medicine should be used with caution in patients with a history of seizure disorder or a family history of seizures since it may worsen the patient's condition. Report any unusual symptoms to the doctor immediately. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This medicine should be administered by a qualified healthcare professional. Inform the doctor if you have a known history of allergy to this medicine. Report to the doctor all your current medicines as well as your medical conditions before receiving this medicine.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works
This medicine works by interfering with certain processes that help the bacteria to grow and increase in number.
Legal Status

Approved

Unknown

Approved

Unknown

Classification

Category

Third generation cephalosporins

Schedule

Schedule H

Ceftizoxime - DrugBank [Internet]. Drugbank.ca. 2018 [cited 10 September 2018]. Available from:

https://www.drugbank.ca/drugs/DB01332

Cefizox®(Ceftizoxime for Injection, USP) [Internet]. Dailymed.nlm.nih.gov. 2018 [cited 10 September 2018]. Available from:

https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=3574df06-fec5-4888-8080-3b817addfb02&type=display

[Internet]. Tajapi.com. 2018 [cited 10 September 2018]. Available from:

https://www.tajapi.com/Pharmaceuticals%20API%20List_4_2011.pdf/Ceftizoxime%20Sodium.pdf

[Internet]. Pillpack.com. 2018 [cited 10 September 2018]. Available from:

https://www.pillpack.com/medication/ceftizoxime-injection.pdf

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Information on this page was last updated on 11 Apr 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.