Cefpirome

Description

Cefpirome is a broad-spectrum antibiotic which is used to treat infections of the respiratory tract, urinary tract, blood, skin and soft tissues, etc. caused by susceptible bacteria. This medicine is not effective against infections caused by viruses such as a viral fever, flu, a common cold, etc. It is not recommended for use in patients less than 18 years of age, except under close observation of a qualified healthcare professional.

Side effects

Major & minor side effects for Cefpirome

  • Skin rash
  • Nausea and vomiting
  • Abdominal pain
  • Diarrhea
  • Headache
  • Shortness of breath
  • Irregular heartbeat
  • Itching of skin
  • Taste and/or smell disturbances

Uses of Cefpirome

What is it prescribed for?

  • Lower Respiratory Tract Infection
  • Skin and soft tissue infections
  • Bacterial Septicemia
  • Infections in neutropenic/ immune compromised patients
  • Urinary tract infection
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Concerns

Commonly asked questions

  • Onset of action
    The effect of this medicine occurs rapidly after an intravenous administration.
  • Duration of effect
    The effect of this medicine lasts for an average duration of 12 to 24 hours.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to cefpirome, any other Beta-lactam antibiotics such as penicillins or cephalosporins, or any other inactive ingredients present in the formulation.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
General warnings

Clostridium difficile-associated diarrhea

Discontinue the use of this medicine as per the doctor's instructions if severe diarrhea occurs after receiving the medicine. This medicine may cause an imbalance in the microbial flora of the large intestine, decreasing the gut-friendly bacteria and promoting the growth of a bacteria called Clostridium difficile, resulting in severe diarrhea.

Drug-resistance

Usage of this medicine without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of development of bacteria that are drug resistant.

Hypersensitivity reactions

This medicine may cause serious and occasionally fatal hypersensitivity reactions including anaphylactic shock in some patients. This risk is especially higher in patients with a history of sensitivity to multiple allergens. If an anaphylactic reaction occurs, the treatment should be discontinued immediately and appropriate corrective measures should be undertaken.

Use in children

This medicine may be used in patients less than 18 years of age only under the close observation of a qualified healthcare professional.

Missed Dose

Since this medicine is administered by a qualified healthcare professional in the clinical or hospital setting, the likelihood of a missed dose is very low. However, if you miss a scheduled appointment for a dose of this medicine, contact your doctor for further instructions.

Overdose

Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Cholera Vaccine

Furosemide

Ethinyl Estradiol

Disease interactions

Renal impairment

This medicine should be used with caution in patients with a known history of kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Liver impairment

This medicine should be used with caution in patients with a known history of liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Gastrointestinal Diseases

This medicine should be used with extreme caution in patients having a history of gastrointestinal diseases, particularly colitis, since it may worsen the patient's condition. Report any incidence of severe diarrhea, abdominal pain, blood in stools, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.
Food interactions
Information not available.
Lab interactions
Information not available.
This medicine will be administered by a qualified healthcare professional in the clinical or hospital setting. Inform the doctor if you have a known history of allergy to this medicine. Report to the doctor all your current medicines as well as your medical conditions before receiving this medicine. Report any undesirable side effects to the doctor promptly.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by interfering with certain processes that help the bacteria to grow and increase in number.
Legal Status

Approved

Unknown

Approved

Unknown

Classification

Category

Fourth generation Cephalosporins

Schedule

Schedule H

[Internet]. Squarepharma.com.bd. 2018 [cited 23 April 2018]. Available from:

https://www.squarepharma.com.bd/downloads/Force.pdf

Cefpirome [Internet]. Pubchem.ncbi.nlm.nih.gov. 2018 [cited 23 April 2018]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/cefpirome

[Internet]. Neisslabs.com. 2018 [cited 23 April 2018]. Available from:

http://neisslabs.com/pdfs/doctors/cefpirome.pdf

[Internet]. Toku-e.com. 2018 [cited 23 April 2018]. Available from:

https://www.toku-e.com/ConvertHtmlToPdf.axd?product=159

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Information on this page was last updated on 24 Oct 2018

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.