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Cefolac XL 200 Tablet
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Cefolac XL 200 Tablet

Manufactured byMacleods Pharmaceuticals Pvt. Ltd.
ContainsCefixime (200 mg) + Cloxacillin (500 mg)
Description
Cefolac XL 200 Tablet is a combination medicine used for the treatment of upper and lower respiratory tract infections and skin and soft tissue infections in adult patients. This medicine is not recommended for use in patients less than 18 years of age.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Cefolac XL 200 Tablet

  • Nausea and Vomiting
  • Diarrhea
  • Abdominal pain
  • Sore mouth and tongue
  • Yellowing of skin and eyes
  • Wheezing
  • Rash
  • Dark or clay colored stools
  • Swelling of face, lips, eyelids, tongue, hands and feet
  • Dizziness
  • Acid or sour stomach
  • Excessive air or gas in stomach
  • Heartburn
  • Indigestion
  • Redness of skin

Uses of Cefolac XL 200 Tablet

What is it prescribed for?

  • Upper Respiratory Tract Infection
  • Lower Respiratory Tract Infection
  • Skin and soft tissue infections
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of this medicine can be observed within 30 minutes of administration of the dose.
  • How long do the effects of this medicine last?
    The effect of this medicine lasts for an average duration of 6 to 8 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. If the medicine is used, the infant should be monitored closely for any undesirable side effects. Alternatively, your doctor may prescribe a safer alternative based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to cefixime, any other beta-lactam antibiotics, cloxacillin, any other antibiotic of the penicillin or cephalosporin group, or any other inactive ingredients present along with these medicines.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. If the medicine is used, the infant should be monitored closely for any undesirable side effects. Alternatively, your doctor may prescribe a safer alternative based on your clinical condition.
General warnings

Sodium

This medicine contains sodium and therefore it should be used carefully in patients requiring sodium restriction (patients with congestive heart failure, high blood pressure, fluid retention, etc). Close monitoring of electrolytes levels and vital signs may be necessary for some patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Clostridium difficile-associated diarrhea

Discontinue the use of this medicine as per the doctor's instructions if severe diarrhea occurs after receiving this medicine. This medicine may cause an imbalance in the microbial flora of the large intestine, decreasing the gut-friendly bacteria and promoting the growth of a bacteria called Clostridium difficile, resulting in severe diarrhea.

Drug-resistance

Usage of this medicine without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of development of bacteria that are drug resistant.

Hypersensitivity reactions

This medicine may cause serious and occasionally fatal hypersensitivity reactions including anaphylactic shock in some patients. This risk is especially high in patients with a history of sensitivity to multiple allergens. If an anaphylactic reaction occurs, the treatment should be discontinued immediately and appropriate corrective measures should be undertaken.

Long-term therapy

Close monitoring of kidney function, liver function, and blood counts is recommended during long-term therapy with this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Bleeding disorders

This medicine should be used with caution in patients with bleeding disorders due to the increased risk of excessive bleeding. Regular monitoring of prothrombin time is necessary in such cases. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Use in pediatrics

This medicine is not recommended for use in patients less than 18 years of age since the safety and efficacy of use are not clinically established.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Amikacin

Chloramphenicol

Nifedipine

Furosemide

Live cholera vaccine

Methotrexate

Tetracycline

Ethinyl Estradiol

Warfarin

Disease interactions

Bone Marrow Depression

This medicine should be used with caution in patients with bone marrow depression due to the increased risk of worsening of the patient's condition. Close monitoring of blood counts is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Colitis

This medicine should be used with extreme caution in patients having a history of gastrointestinal diseases, particularly colitis, since it may worsen the patient's condition. Report any incidence of severe diarrhea, abdominal pain, blood in stools, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Kidney disease

This medicine should be used with caution in patients with renal diseases due to the increased risk of serious adverse effects. Close monitoring of kidney function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.
Food interactions
Information not available.
Lab interactions

Coombs test

Report the use of this medicine to the doctor if you are undergoing this test. A false positive result may be obtained if this test is performed while taking this medicine. Do not stop the use of any medicine without consulting your doctor.

Urine ketones test

Report the use of this medicine to the doctor if you are undergoing a urine ketones test. A false positive result may be obtained if this test is performed while taking this medicine. Do not stop the use of any medicine without consulting your doctor.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take this medicine on an empty stomach. The effectiveness of this medicine may be reduced in the presence of food. Do not consume in larger or smaller amounts than advised. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

To be taken on an empty stomach

To be taken as instructed by doctor

Does not cause sleepiness

How it works
This medicine works by interfering with certain processes that help the bacteria to grow and increase in number. This helps in stopping the growth and multiplication of bacteria and eventually kills them.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Third generation cephalosporins, Penicillinase resistant penicillins

Schedule

Schedule H

[Internet]. 2017 [cited 6 March 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/14540

[Internet]. 2017 [cited 4 October 2017]. Available from:

http://www.lupinpharmaceuticals.com/pdf/09/SUPRAX%20Common%20PI%20.pdf

Cloxacillin - DrugBank [Internet]. Drugbank.ca. 2018 [cited 16 March 2018]. Available from:

https://www.drugbank.ca/drugs/DB01147

[Internet]. Just.edu.jo. 2018 [cited 16 March 2018]. Available from:

http://www.just.edu.jo/DIC/AZLibrary/Cloxacillin.pdf

[Internet]. Pdf.hres.ca. 2018 [cited 16 March 2018]. Available from:

https://pdf.hres.ca/dpd_pm/00036515.PDF
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Information on this page was last updated on 25 May 2018

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