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Castrov-LZ Tablet

Manufactured byADEN HEALTHCARE
ContainsCefuroxime (500 mg) + Linezolid (600 mg)
Description
Castrov-LZ Tablet is a combination medicine that consists of cefuroxime and linezolid. It is used in the treatment of bacterial infections of the ear, sinus, throat, urinary tract, lungs and blood. It works by stopping the growth and multiplication of bacteria. It is not effective against infections caused by viruses. Castrov-LZ Tablet can cause side effects like anaemia, decrease in white blood cell and platelet count, stomach pain, indigestion, diarrhoea, nausea, vomiting and flatulence. Seek medical attention if any of these side effects persist or worsen. It may cause dizziness or drowsiness so avoid any activity that requires concentration such as driving after taking this medicine. Inform your doctor if you feel pain in your tendons after using this medicine. Do not take this medicine if you are allergic to it. Castrov-LZ Tablet can be taken with or without food at the same time every day. Take this medicine same time every day. Be sure to complete the course as directed by your doctor in order to avoid bacterial resistance to this medicine. Avoid consuming alcohol while taking this medicine as it can cause excessive drowsiness. Do not take this with foods like aged cheese, cured meats, some tropical fruit and beer as they can decrease its efficiency. Castrov-LZ Tablet may not be suitable for all people. Hence, inform your doctor if you have any kidney or liver problems before starting the treatment with this medicine. This medicine is not recommended to be used in pregnancy and breastfeeding, consult your doctor before using Castrov-LZ Tablet

Side effects

Major & minor side effects for Castrov-LZ Tablet

  • Skin Rash
  • Headache
  • Nausea or vomiting
  • Convulsions
  • Irregular heartbeat
  • Change in taste
  • Trouble sleeping
  • Dark or Clay colored stools
  • Dizziness
  • Excessive air or gas in stomach
  • Heart burn
  • Chest pain
  • Fever
  • Diarrhoea
  • Acid or sour stomach
  • Flatulence

Uses of Castrov-LZ Tablet

What is it prescribed for?

  • Community acquired pneumonia
  • Active urinary tract infection
  • Acute bronchitis
  • Pharyngitis/Tonsilitis
  • Gonorrhoea
  • Syphilis
  • Skin and soft tissue infections
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The time taken for Castrov-LZ Tablet to produce its effect is not known.
  • How long do the effects of this medicine last?
    The amount of time for which Castrov-LZ Tablet remains active in the body is not known.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Castrov-LZ Tablet
  • Can this medicine be taken during pregnancy?
    Castrov-LZ Tablet is not recommended for use in pregnancy unless absolutely necessary. Consult your doctor before taking this medication.
  • Can this medicine be taken while breast-feeding?
    Castrov-LZ Tablet is known to be excreted in breastmilk and it may harm your infant. It is not recommended for use during breastfeeding unless absolutely necessary. Consult your doctor before taking this medication.

Allergy

Avoid taking Castrov-LZ Tablet if you are allergic to it. Seek immediate medical attention if you notice any symptoms of allergic reactions such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.
Warnings for special population

Pregnancy

Castrov-LZ Tablet is not recommended for use in pregnancy unless absolutely necessary. Consult your doctor before taking this medication.

Breast-feeding

Castrov-LZ Tablet is known to be excreted in breastmilk and it may harm your infant. It is not recommended for use during breastfeeding unless absolutely necessary. Consult your doctor before taking this medication.
General warnings

Decrease blood cell count

Caution should be maintained while taking Castrov-LZ Tablet as it may decrease your blood cell count. Your doctor may advise blood tests to monitor your blood cell count while using this medicine.

Optic neuropathy

Prolong therapy with Castrov-LZ Tablet may cause vision problems when you take this medicine for more than 28 days. Any symptoms of changes in vision should be informed to the doctor.

Antibiotic resistance

Finish your entire course of treatment with Castrov-LZ Tablet, even if the condition gets better after taking a few doses to avoid antibiotic resistance (a condition where microbes evolve mechanisms that protect them from the effects of antibiotics). If you still feel unwell after completing your antibiotic course, consult your doctor.

Lactic acidosis

Lactic acidosis is a condition in which lactate builds up in the blood and makes it acidic. This condition can damage the liver, kidneys and other organs of your body. Using Castrov-LZ Tablet should be avoided in this condition as it may worsen your condition.

Allergic skin reaction

Castrov-LZ Tablet is likely to cause allergic skin reactions. Seek immediate medical attention if you notice any symptoms such as skin rash, or severe itching/swelling (especially of the face/tongue/throat), especially on the face.

Diarrhoea

Castrov-LZ Tablet can cause diarrhoea because it may also kill the helpful bacteria in your stomach or intestine. Get emergency medical help if you experience severe diarrhoea that is watery or bloody. Consult your pharmacist/doctor before taking anti-diarrhoeal medication.

Driving or operating machinery

Castrov-LZ Tablet may cause dizziness, confusion, or fits. Do not drive a vehicle or operate machinery after taking this medicine.

Liver disease

Castrov-LZ Tablet may increase liver enzyme levels and cause liver swelling. Inform your doctor if you have liver problems before taking this medicine as it may increase the risk of liver damage. Your doctor may adjust the dose of this medicine and may advise tests to monitor your liver function as required.

Seizures

Use Castrov-LZ Tablet with caution if you have seizures or fits because it can worsen the condition and even trigger a seizure. Seizure medicines should be continued by consulting your doctor in case you have a pre-existing seizure disorder. Your doctor may adjust the dose of this medicine if required.

Hypertension

Castrov-LZ Tablet is not be recommended for use if you have uncontrolled blood pressure, pheochromocytoma, thyrotoxicosis, etc., unless absolutely necessary because it may worsen these conditions.

Missed Dose

Take the missed dose of Castrov-LZ Tablet as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Never take more than the prescribed dose of Castrov-LZ Tablet. Seek emergency medical treatment if you suspect that you might have taken an overdose of this medicine.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Furosemide

Ethinyl Estradiol

Warfarin

Amikacin

Ondansetron

Cholera Vaccine (live)

Glimepiride

Disease interactions

Liver disease

If you have liver problems, maintain caution while taking Castrov-LZ Tablet due to the risk of liver damage. Your doctor may adjust the dose based on your clinical condition.

Colitis

Avoid taking Castrov-LZ Tablet if you experience severe diarrhoea, abdominal pain, and blood in stools after taking it. Inform the doctor if you have any gastrointestinal problems. Drink adequate amounts of water to prevent dehydration.

Kidney diseases

High doses and prolonged use of Castrov-LZ Tablet may increase the risk of kidney injury. Your doctor may advise tests to monitor your kidney function.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Castrov-LZ Tablet with or without food, as instructed by your doctor. Do not take more than the prescribed dose. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor. Do not consume cheese, processed meats, soy sauce or alcohol as these may raise your blood pressure Keep away from the reach of children and pets. Do not use it after the expiry date. Ensure that unused medicine is disposed of properly. Do not give your medicine to other people even if their condition appears to be the same as yours.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Causes sleepiness

How it works
Cefuroxime prevents the formation of bacterial cell walls, thereby killing the bacteria and stopping the spread. Linezolid interferes with protein synthesis which is essential for bacterial growth. Thus together they can stop the growth and spread of bacteria.
Legal Status

Banned

Unknown

Unknown

Unknown

Classification

Category

Oxazolidinone antibiotics, Second generation cephalosporins, Beta-lactamase inhibitors

Schedule

Schedule H

Drugs, H., 2021. Linezolid: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 8 September 2021].

https://medlineplus.gov/druginfo/meds/a602004.html>

Medicines.org.uk. 2021. Linezolid 600mg film-coated tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 8 September 2021].

https://www.medicines.org.uk/emc/medicine/32732>

Drugs, H., 2021. Cefuroxime: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 8 September 2021].

https://medlineplus.gov/druginfo/meds/a601206.html>

Dailymed.nlm.nih.gov. 2021. DailyMed - CEFUROXIME AXETIL tablet. [online] Available at: < [Accessed 8 September 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=faef39e9-d793-4191-a728-310f6fab759d>

Pubchem.ncbi.nlm.nih.gov. 2021. Cefuroxime. [online] Available at: < [Accessed 8 September 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Cephuroxime>

Medicines.org.uk. 2021. Linezolid 600 mg film-coated tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 8 September 2021].

https://www.medicines.org.uk/emc/product/5119/smpc#gref>

Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 8 September 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/021130s016,021131s013,021132s014lbl.pdf>
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Information on this page was last updated on 21 Sep 2021

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