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CartiSafe-D OD Tablet

Manufactured byJENBURKT PHARMACEUTICALS LTD
ContainsDiacerein (50 mg) + Glucosamine (1500 mg)
Description

CartiSafe-D OD Tablet is a combination medicine used for the treatment of osteoarthritis of the knee and/or hip joints in adult patients. Patients are advised to undergo appropriate physical therapy and rest along with this medicine to obtain the best possible effect. It is not recommended for use in children and adolescents.

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Side effects

Major & minor side effects for CartiSafe-D OD Tablet

  • Nausea
  • Constipation
  • Heartburn
  • Headache
  • Diarrhea
  • Stomach discomfort and pain
  • Vomiting
  • Yellowing of skin and eyes
  • Intense yellow urine
  • Increase in liver enzyme levels
  • Allergic skin reaction

Uses of CartiSafe-D OD Tablet

What is it prescribed for?

  • Osteoarthritis
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to glucosamine, shellfish, diacerein, any other anthraquinones, or any other inactive ingredients present along with the formulation.

Severe kidney damage

This medicine is not recommended for use in patients having a severe impairment of kidney function due to the increased risk of serious adverse effects.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Diabetes mellitus

This medicine should be used with caution in patients with a known history of diabetes mellitus due to the increased risk of alteration of blood glucose levels. Close monitoring of blood glucose levels is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Hyperlipidemia

This medicine should be used with caution in patients with a known history of hyperlipidemia due to the increased risk of worsening of the patient's condition. Close monitoring of liver enzymes and cholesterol levels is recommended during treatment with this supplement. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Use in children

This medicine is not recommended for use in children since the safety and efficacy of use are not clinically established.

Drowsiness

This medicine may cause drowsiness in rare cases. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you experience drowsiness during treatment with this medicine.

Diarrhea

Use of this medicine may cause diarrhea or loose stools in the first few days of treatment. Contact your doctor if the complication is not resolved within 3-4 days.

Antibiotic therapy

This medicine should not be taken with antibiotics since the risk of gastric irritation and persistent diarrhea is significantly high in such cases. Your doctor may make appropriate changes to your therapy based on your clinical condition.

Diagnostic tests

It is recommended to monitor liver function, kidney function, complete blood count, and urine tests every six months during treatment with this medicine.

Intense yellowing of urine

Use of this medicine may cause intense yellow coloration of the urine. This is mainly due to the excretion of end products and may not be indicative of any complication.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Aluminium Hydroxide/Magnesium Hydroxide

Warfarin

Amoxycillin

Laxatives

Dicumarol

Anisindione

Disease interactions

Irritable bowel syndrome

This medicine should be used with caution in patients having an irritable bowel or other associated conditions of the gastrointestinal tract due to an increase in the risk of severe adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Kidney Disease

This medicine is not recommended for use in patients having severe impairment of the normal kidney function. Appropriate diagnostic tests must be performed to rule out any kidney disease before treatment with this medicine is initiated. Replacement with a suitable alternative may be required based on the clinical condition of the patient.
Food interactions
A diet rich in dietary fibers and phytates may interfere with the absorption of this medicine. Hence, administration of this medicine with a diet rich in fibers and phytates should be avoided. Your doctor/dietitian may suggest appropriate changes in your diet based on your clinical condition.
Lab interactions
Information not available.
Take this medicine exactly as prescribed by the doctor. Do not take in larger or smaller quantities than recommended. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

To be taken immediately after food

To be taken as instructed by doctor

May cause sleepiness

How it works
Diacerein works by blocking the actions of a certain specific protein that causes swelling, pain, and degradation of cartilage at bone joints. Glucosamine works as a precursor for the production of certain chemicals which are responsible for building tendons, ligaments, thick fluid around the joints, and cartilage.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Miscellaneous analgesics, Nonsteroidal anti-inflammatory agents, Analgesic combinations

Schedule

Schedule H

Glucosamine - DrugBank [Internet]. Drugbank.ca. 2017 [cited 31 August 2017]. Available from:

https://www.drugbank.ca/drugs/DB01296

Glucosamine sulfate: MedlinePlus Supplements [Internet]. Medlineplus.gov. 2017 [cited 31 August 2017]. Available from:

https://medlineplus.gov/druginfo/natural/807.html

Diacerein - DrugBank [Internet]. Drugbank.ca. 2017 [cited 13 July 2017]. Available from:

https://www.drugbank.ca/drugs/DB11994

[Internet]. 2017 [cited 13 July 2017]. Available from:

http://highnoon-labs.com/wp-content/uploads/2015/04/Artrodar-Insert.pdf
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Information on this page was last updated on 4 Jul 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.