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Cardace Am (5/10 mg) Tablet
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Cardace Am (5/10 mg) Tablet

Manufactured bySanofi India Ltd.
ContainsAmlodipine (5 mg) + Ramipril (10 mg)
Description
Cardace Am (5/10 mg) Tablet is a combination medicine used for the treatment of high blood pressure. This medicine is not recommended for use in patients below 18 years of age. Patients are advised to follow a strict exercise and diet regimen along with this medicine to get the best possible effect.
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Side effectsConcernsUsageRelated products

Side effects

Major & minor side effects for Cardace Am (5/10 mg) Tablet

  • Blurred vision
  • Sweating
  • Dizziness
  • Unusual tiredness and weakness
  • Back pain
  • Chest tightness
  • Increased heartbeat
  • Cough
  • Diarrhea
  • Vomiting
  • Swelling of ankles or feet
  • Difficulty in breathing
  • Redness of face, neck, arms and chest
  • Muscle pain
  • Heartburn
  • Acid or sour stomach
  • Stomach pain
  • Anxiety

Uses of Cardace Am (5/10 mg) Tablet

What is it prescribed for?

  • Hypertension
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of this medicine can be observed within 1 to 2 hours of administration of the dose.
  • How long do the effects of this medicine last?
    This effect of this medicine lasts for an average duration of approximately 24 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, lightheadedness, and fainting. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
  • Is this a habit forming medicine?
    No habit forming tendency has been reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women except in life-threatening conditions. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to amlodipine, other calcium-channel blockers, ramipril, other ACE inhibitors, or any other inactive ingredients present along with them.

Aliskiren

Coadministration of aliskiren and this combination medicine is not recommended due to the increased risk of serious adverse effects. This risk is especially higher in the elderly population and in patients with diabetes and kidney diseases.

Liver impairment

This medicine is not recommended for use in patients with liver impairment due to the increased risk of worsening of the patient's condition.

Severe renal impairment

This medicine is not recommended for use in patients with severe renal impairment (CrCl < 40 ml/min) since it may worsen the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women except in life-threatening conditions. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.
General warnings

Hypotension

Symptomatic hypotension may occur in patients with volume depletion or patients who are treated with high-dose diuretics. It is advised to correct this condition before initiating treatment with this combination medicine.

Hyperkalemia

This medicine may increase the potassium levels in the blood (hyperkalemia). This may cause serious side effects such as fatal cardiac rhythm irregularities. It is advised to avoid potassium-rich foods (potatoes, bananas) and other medicines that may increase potassium levels (potassium-sparing diuretics and potassium supplements) during treatment with this medicine.

Pediatric population

This medicine is not recommended for use in children since the safety and efficacy of use are not clinically established.

Cough

This medicine may cause a persistent nonproductive cough in some patients. It is resolved when the medicine is discontinued.

Coronary artery diseases

This medicine should be used with caution in patients with coronary artery diseases since it may worsen the patient's condition. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.

Driving and operating machines

This medicine may cause dizziness or drowsiness in some patients. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Impaired kidney function

This medicine should be used with caution in patients with kidney diseases due to the increased risk of worsening of the patient's condition. Close monitoring of renal function is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be necessary in some cases based on the clinical condition.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, lightheadedness, and fainting. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
Interaction with Medicine

Carbamazepine

Itraconazole

Losartan

Corticosteroids

Rifampicin

Aliskiren

Insulin

Nonsteroidal anti-inflammatory medicines

Disease interactions

Angioedema

This medicine is not recommended for use in patients with a history of angioedema or a family history of angioedema due to the increased risk of recurrent symptoms. Report any incidence of swelling of the face, lips, and eyes to the doctor on priority. Replacement with a suitable alternative may be required based on the clinical condition.

Cardiogenic shock

This medicine is not recommended for use in patients suffering from a cardiogenic shock since it may worsen the patient's condition.
Food interactions
Consumption of grapefruit juice is not recommended during treatment with this medicine due to the increased risk of severe adverse effects such as dizziness, headache, swelling of hands and feet, etc.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take this medicine exactly as advised by your doctor. It can be taken with or without food. Do not take in larger amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Amlodipine relaxes the heart muscles and the blood vessels. Ramipril relaxes the blood vessels and promotes the smooth flow of blood. Their combination is thus effective in reducing the blood pressure.
Legal Status

Approved

Unknown

Approved

Unknown

Classification

Category

Calcium channel blocking agents, Angiotensin converting enzyme inhibitors, ACE inhibitors with calcium channel blocking agents, Antihypertensive combinations

Schedule

Schedule H

[Internet]. 2017 [cited 4 October 2017]. Available from:

http://products.sanofi.in/Cardace-AM.pdf

[Internet]. 2017 [cited 4 October 2017]. Available from:

http://mri.cts-mrp.eu/download/AT_H_0469_005_FinalPL.pdf

[Internet]. 2017 [cited 8 March 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/30283

Ramipril: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 8 March 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a692027.html

DailyMed - Ramipril capsule [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 8 March 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=8b59207a-ea5c-4697-a8b6-94c3015a00de

Amlodipine: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 7 March 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a692044.html

[Internet]. 2017 [cited 7 March 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/24889

DailyMed - Amlodipine tablet [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 7 March 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1cec7a02-b7a5-49e1-ab64-3a4dab4149d2
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Information on this page was last updated on 8 Nov 2017

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