Carbimazole

Description

Carbimazole is used for the treatment of hyperthyroidism, a condition where the thyroid gland produces an excessive amount of thyroid hormones. It is also used to relieve the symptoms of hyperthyroidism before thyroid surgery or radioactive iodine treatment.

Side effects

Major & minor side effects for Carbimazole

  • Sore throat
  • Mouth ulcers
  • Headache
  • Yelllow eyes and skin
  • Weakness
  • Rash
  • Fever

Uses of Carbimazole

What is it prescribed for?

  • Hyperthyroidism
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to Carbimazole or any other inactive ingredients present along with it.

Severe liver impairment

This medicine is not recommended for use in patients with severe liver impairment due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Use in children

This medicine is not recommended for use in patients below 2 years of age since the safety and efficacy of use are not clinically established.

Bleeding Disorders

This medicine should be used with extreme caution in patients suffering from bleeding disorders due to the increased risk of worsening of the patient's condition. Close monitoring of prothrombin time/INR is necessary while taking this medicine. Appropriate dose adjustment or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Surgeries

This medicine should be used with extreme caution while planning for surgeries since it may cause excessive bleeding. Close monitoring of prothrombin time is necessary while taking this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be necessary in some cases based on the clinical condition.

Hypothyroidism

This medicine should be used with caution due to the risk of hypothyroidism (low thyroid hormone levels). This risk is especially higher if the medicine is used for a prolonged period of time. Close monitoring of thyroid function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Liver diseases

This medicine should be used with extreme caution in the patients suffering from liver diseases due to the increased risk of hepatotoxicity. Close monitoring of liver function tests is necessary while taking this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition. This medicine is not recommended for use in patients with severe liver impairment.

Missed Dose

The missed dose should be taken as soon as possible. It is advisable to skip the missed dose if it is already time for your next scheduled dose. Do not use extra medicine to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Acenocoumarol

Digoxin

Aminophylline

Theophylline

Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine exactly as advised by your doctor. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the course of treatment is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Effect on sleep is not established

How it works
It inhibits the synthesis of thyroid hormone to reduce thyroid hormone levels and thus relieves associated symptoms.
Legal Status

Approved

Unknown

Unknown

Approved

Classification

Category

Antithyroid agents

Schedule

Schedule H

[Internet]. Medicines.org.uk. 2018 [cited 7 September 2018]. Available from:

https://www.medicines.org.uk/emc/files/pil.5025.pdf

[Internet]. Mhra.gov.uk. 2018 [cited 7 September 2018]. Available from:

http://www.mhra.gov.uk/home/groups/spcpil/documents/spcpil/con1430459462843.pdf

[Internet]. Mhra.gov.uk. 2018 [cited 7 September 2018]. Available from:

http://www.mhra.gov.uk/home/groups/spcpil/documents/spcpil/con1459317496607.pdf

Carbimazole [Internet]. Pubchem.ncbi.nlm.nih.gov. 2018 [cited 7 September 2018]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/Carbimazole

Carbimazole - DrugBank [Internet]. Drugbank.ca. 2018 [cited 7 September 2018]. Available from:

https://www.drugbank.ca/drugs/DB00389

[Internet]. Medsafe.govt.nz. 2018 [cited 7 September 2018]. Available from:

http://www.medsafe.govt.nz/profs/Datasheet/n/Neo-Mercazoletab.pdf

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Information on this page was last updated on 23 Jan 2019

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